| Project/Area Number |
19590731
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Osaka City University |
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Principal Investigator |
TOMINAGA Kazunari Osaka City University, 大学院・医学研究科, 准教授 (80336768)
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|---|
| Co-Investigator(Kenkyū-buntansha) |
FUJIWARA Yasuhiro 大阪市立大学, 大学院・医学研究科, 准教授 (40285292)
WATANABE Toshio 大阪市立大学, 大学院・医学研究科, 准教授 (50336773)
TANIGAWA Tetsuya 大阪市立大学, 大学院・医学研究科, 講師 (70423879)
樋口 和秀 大阪医科大学, 医学部, 教授 (20218697)
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| Co-Investigator(Renkei-kenkyūsha) |
HIGUCHI Kazuhide 大阪医科大学, 医学部, 教授 (20218697)
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| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 内科 / 消化器病学 / 味覚 / 分子イメージング / 受容体 / 化学受容器 / 感覚受容器 / 知覚過敏性 / イメージング |
|---|
| Research Abstract |
Gene expression of 22 kinds of T2R families, bitter taste receptors, was ubiquitously observed in most digestive tracts from the esophagus to the colon by PCR methods. Unfortunately, the detailed localization of them could not be proved even by using various probes of molecular methods. However, a part of the bitter taste receptors may be associated with the delay of gastric emptying.
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