Role of arterial wave reflection in cerebral microvascular damage

• Project/Area Number: 19590848
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: Tohoku University
• Principal Investigator: HASHIMOTO Junichiro Tohoku University, 大学院・薬学研究科, 准教授 (50333795)
• Co-Investigator(Kenkyū-buntansha): KAJIKAWA Shinya 東北学院大学, 工学部, 教授 (80290691)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 循環器 / 高血圧 / 脳血管障害 / 臨床 / 波反射 / 血流 / 動脈硬化 / 生理学 / 動脈研化

Research Abstract

一般成人において、動脈波反射に関連する圧脈波指標は無症候性ラクナ梗塞や白質病変を含む脳微小血管障害と有意に関連する。脳の微小血管障害と腎の微小血管障害(アルブミン尿)は相互連関し、その結びつきには大動脈硬化が介在する。高血圧患者において、全身の大・小動脈の構造的・機能的変化に起因する動脈波反射の増加は、脳への血圧と血流の拍動を増加させ、これらが脳微小血管障害を進展させると推測される。

Research Products

• [Journal Article] Some mechanical aspects of arterial aging : physiological overview based on pulse wave analysis (2009)
  • Author(s): Junichiro Hashimoto, Sadayoshi Ito
  • Journal Title: Ther Adv Cardiovasc Dis (In press)
  • Peer Reviewed
• [Journal Article] Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men : the Ohasama study (2009)
  • Author(s): Takuo Hirose, Junichiro Hashimoto, et.al.
  • Journal Title: Am J Hypertens 22 Pages: 294-299
  • Peer Reviewed
• [Journal Article] Stroke risk and antihypertensive drug treatment in the general population : the Japan arteriosclerosis longitudinal study (2009)
  • Author(s): Kei Asayama, Junichiro Hashimoto, et.al.
  • Journal Title: J Hypertens 27 Pages: 357-364
  • Peer Reviewed
• [Journal Article] Large artery stiffening as a link between cerebral lacunar infarction and renal albuminuria (2008)
  • Author(s): Junichiro Hashimoto, et.al(3名中1番目)
  • Journal Title: Am J Hypertens 21 Pages: 1304-1309
  • Peer Reviewed
• [Journal Article] Different role of wave reflection magnitude and timing on left ventricular mass reduction during antihypertensive treatment (2008)
  • Author(s): Junichiro Hashimoto, et.al(5名中1番目)
  • Journal Title: J Hypertens 26 Pages: 1017-1024
  • Peer Reviewed
• [Journal Article] Association between wasted pressure effort and left ventricular hypertrophy in hypertension: Influence of arterial wave reflection (2008)
  • Author(s): Junichiro Hashimoto, et.al(4名中1番目)
  • Journal Title: Am J Hypertens 21 Pages: 329-333
  • Peer Reviewed
• [Journal Article] Cerebro-renal connection: Involvement of large artery stiffening in microvascular organ damage (2008)
  • Author(s): Junichiro Hashimoto, et.al(3名中1番目)
  • Journal Title: Hypertension 52
  • Peer Reviewed
• [Journal Article] Association of microalbuminuria with brachial-ankle pulse wave velocity: The Ohasama study (2008)
  • Author(s): Tomofumi Ishikawa, Junichiro Hashimoto, et.al(16名中2番目)
  • Journal Title: Am J Hypertens 21 Pages: 413-418
  • Peer Reviewed
• [Journal Article] Is arterial stiffness better than blood pressure in predicting cardiovascular risk? (2008)
  • Author(s): Junichiro Hashimoto, Michael F. O'Rourke
  • Journal Title: Curr Cardiovasc Risk Rep 2 Pages: 133-140
  • Peer Reviewed
• [Journal Article] A modifiable cardiovascular risk factor? (2008)
  • Author(s): Michael F. O'Rourke, Junichiro Hashimoto. Arterial stiffness
  • Journal Title: J Cardiopulm Rehabil Prev 28 Pages: 225-237
  • Peer Reviewed
• [Journal Article] 左室重量減少のための降圧治療モニタリング (2008)
  • Author(s): 橋本潤一郎
  • Journal Title: Arterial Stiffness 14 Pages: 64-65
• [Journal Article] AIで評価される反射波のタイミングや大きさは、大血管・小血管のどのような変化によって変わりますか? (2008)
  • Author(s): 橋本潤一郎
  • Journal Title: Arterial Stiffness 14 Pages: 112-113
• [Journal Article] Large artery stiffening as a link between cerebral lacunar infarction and renal albuminuria (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Journal Title: Am J Hypertens 21 Pages: 1304-1309
  • Peer Reviewed
• [Journal Article] Different role of wave reflection magnitude and timing on left ventricular mass reduction during antihypertensive treatment (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Journal Title: J Hypertens 26 Pages: 1017-1024
  • Peer Reviewed
• [Journal Article] Association between wasted pressure effort and left ventricular hypertrophy in hypertension : Influence of arterial wave reflection (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Journal Title: Am J Hypertens 21 Pages: 329-333
  • Peer Reviewed
• [Journal Article] Cerebro-renal connection : Involvement of large artery stiffening in microvascular organ damage (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Journal Title: Hypertension 52
  • Peer Reviewed
• [Journal Article] Day-by-day variability of blood pressure and heart rate at home as a novel predictor of prognosis : the Ohasama study (2008)
  • Author(s): Masahiro Kikuya, Junichiro Hashimoto, et.al.
  • Journal Title: Hypertension 52 Pages: 1045-1050
  • NAID: 120003728008
  • Peer Reviewed
• [Journal Article] Increased expression of adrenomedullin 2/intermedin in rat hearts with congestive heart failure (2008)
  • Author(s): Takuo Hirose, Junichiro Hashimoto, et.al.
  • Journal Title: Eur J Heart Fail 10 Pages: 840-849
  • Peer Reviewed
• [Journal Article] Proposal of a risk-stratification system for the Japanese population based on blood pressure levels : the Ohasama study (2008)
  • Author(s): Kei Asayama, Junichiro Hashimoto, et.al.
  • Journal Title: Hypertens Res 31 Pages: 1315-1322
  • NAID: 10024360610
  • Peer Reviewed
• [Journal Article] Difference between home and office blood pressures among treated hypertensive patients from the J-HOME study (2008)
  • Author(s): Tsuyoshi Horikawa, Junichiro Hashimoto, et.al.
  • Journal Title: Hypertens Res 31 Pages: 1115-1123
  • Peer Reviewed
• [Journal Article] Predictive value of ambulatory heart rate in the Japanese general population : the Ohasama study (2008)
  • Author(s): Atushi Hozawa, Junichiro Hashimoto, et.al.
  • Journal Title: J Hypertens 26 Pages: 1571-1576
  • Peer Reviewed
• [Journal Article] Optimal cutoff point of waist circumference and use of home blood pressure as a definition of metabolic syndrome : The Ohasama study (2008)
  • Author(s): Atsushi Sato, Junichiro Hashimoto, et.al.
  • Journal Title: Am J Hypertens 21 Pages: 514-520
  • Peer Reviewed
• [Journal Article] Prevalence of masked hypertension in subjects treated with antihypertensive drugs as assessed by morning versus evening home blood pressure measurements : the J-Home study (2008)
  • Author(s): Taku Obara, Junichiro Hashimoto, et.al.
  • Journal Title: Clin Exp Hypertens 30 Pages: 277-287
  • Peer Reviewed
• [Journal Article] Time-dependent effects of imidapril administration in patients with morning hypertension measured as home blood pressure (2008)
  • Author(s): Takako Shibasaki, Junichiro Hashimoto, et.al.
  • Journal Title: Clin Exp Hypertens 30 Pages: 243-254
  • Peer Reviewed
• [Journal Article] Association of microalbuminuria with brachial-ankle pulse wave velocity : The Ohasama study (2008)
  • Author(s): Tomofumi Ishikawa, Junichiro Hashimoto, et.al.
  • Journal Title: Am J Hypertens 21 Pages: 413-418
  • Peer Reviewed
• [Journal Article] Involvement of carotid baroreceptor function in blood pressure control in the chronic phase : effect on 24-hour ambulatory blood pressure (2008)
  • Author(s): Eiji Ino-Oka, Junichiro Hashimoto, et.al.
  • Journal Title: Clin Exp Hypertens 30 Pages: 69-78
  • Peer Reviewed
• [Journal Article] Cost-effectiveness of the introduction of home blood pressure in patients with office hypertension (2008)
  • Author(s): Hidefumi Fukunaga, Junichiro Hashimoto, et.al.
  • Journal Title: J Hypertens 26 Pages: 685-690
  • Peer Reviewed
• [Journal Article] Increased gene expression of urotensin II-related peptide in the hearts of rats with congestive heart failure (2008)
  • Author(s): Takashi Nakayama, Junichiro Hashimoto, et.al.
  • Journal Title: Peptides 29 Pages: 801-808
  • Peer Reviewed
• [Journal Article] Home blood pressure measurements associated with better blood pressure control : J-HOME study (2008)
  • Author(s): Taku Obara, Junichiro Hashimoto, et.al.
  • Journal Title: J Hum Hypertens 22 Pages: 197-204
  • Peer Reviewed
• [Journal Article] Principal results of the Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS) (2008)
  • Author(s): JATOS Study Group
  • Journal Title: Hypertens Res 31 Pages: 2115-2127
  • Peer Reviewed
• [Journal Article] Is arterial stiffness better than blood pressure in predicting cardiovascular risk? (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Journal Title: Curr Cardiovasc Risk Rep 2 Pages: 133-140
  • Peer Reviewed
• [Journal Article] Arterial stiffness : A modifiable cardiovascular risk factor? (2008)
  • Author(s): Michael F. O'Rourke, Junichiro Hashimoto
  • Journal Title: J Cardiopulm Rehabil Prev 28 Pages: 225-237
  • Peer Reviewed
• [Journal Article] Different role of wave reflection magnitude and timing on left ventricular mass reduction during antihypertensive treatment (2008)
  • Author(s): Junichiro Hashimoto, et. al.
  • Journal Title: J Hypertens 26 Pages: 1017-1024
  • Peer Reviewed
• [Journal Article] Association between wasted pressure effort and left ventricular hypertrophy in hypertension: Influence of arterial wave reflection (2008)
  • Author(s): Junichiro Hashimoto, et. al.
  • Journal Title: Am J Hypertens 21 Pages: 329-333
  • Peer Reviewed
• [Journal Article] Association of microalbuminuria with brachial-ankle pulse wave velocity: The Ohasamastudy (2008)
  • Author(s): Tomofumi Ishikawa, Junichiro Hashimoto, et. al.
  • Journal Title: Am J Hypertens 413-418 Pages: 413-418
  • Peer Reviewed
• [Journal Article] Is arterial stiffness better than blood pressure in predicting cardiovascular risk? (2008)
  • Author(s): Junichiro Hashimoto, et. al.
  • Journal Title: Curr Cardiovasc Risk Rep 2 Pages: 133-140
  • Peer Reviewed
• [Journal Article] Arterial stiffness: A modifiable cardiovascular risk factor? (2008)
  • Author(s): Michael F. O'Rourke, Junichiro Hashimoto
  • Journal Title: J Cardiopulm Rehabil Prev (In press)
  • Peer Reviewed
• [Journal Article] Involvement of carotid baroreceptor function in blood pressure control in the chronic phase: effect on 24-hour ambulatory blood pressure (2008)
  • Author(s): Eiji Ino-Oka, Junichiro Hashimoto, et. al.
  • Journal Title: Clin Exp Hypertens 30 Pages: 69-78
  • Peer Reviewed
• [Journal Article] Cost-effectiveness of the introduction of home blood pressure in patients with office hypertension (2008)
  • Author(s): Hidefumi Fukunaga, Junichiro Hashimoto, et. al.
  • Journal Title: J Hypertens 26 Pages: 685-690
  • Peer Reviewed
• [Journal Article] Increased gene expression of urotensin II-related peptide in the hearts of rats with congestive heart failure (2008)
  • Author(s): Takashi Nakayama, Junichiro Hashimoto, et. al.
  • Journal Title: Peptide (In press)
  • Peer Reviewed
• [Journal Article] Home blood pressure measurements associated with better blood pressure control: J-JOME study (2008)
  • Author(s): Taku Obara, Junichiro Hashimoto, et. al.
  • Journal Title: J Hum Hypertens (In press)
  • Peer Reviewed
• [Journal Article] Monitoring of antihypertensive therapy for reduction in left ventricular mass (2007)
  • Author(s): Junichiro Hashimoto, et.al(3名中1番目)
  • Journal Title: Am J Hypertens 20 Pages: 1229-1233
  • Peer Reviewed
• [Journal Article] Indices of pulse wave analysis are better predictors of left ventricular mass reduction than cuff pressure (2007)
  • Author(s): Junichiro Hashimoto, et.al(3名中1番目)
  • Journal Title: Am J Hypertens 20 Pages: 378-384
  • Peer Reviewed
• [Journal Article] Mechanical factors in arterial aging : a clinical perspective (2007)
  • Author(s): Michael F. O'Rourke, Junichiro Hashimoto
  • Journal Title: J Am Coll Cardiol 50 Pages: 1-13
  • Peer Reviewed
• [Journal Article] AIと動脈硬化リスク (2007)
  • Author(s): 橋本潤一郎
  • Journal Title: 血圧 14 Pages: 49-54
• [Journal Article] 脈波分析の指標はカフ血圧よりも優れた左室重量減少の予測因子である (2007)
  • Author(s): 橋本潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 70-71
• [Journal Article] 最高血圧は末梢ほど高いはずですが、HEM-9000AIでの測定で、中心血圧が上腕血圧より高い場合があるのはなぜでしょうか? (2007)
  • Author(s): 橋本潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 106-106
• [Journal Article] 動脈壁硬化と心電図上左室肥大の関係 : 大迫研究 (2007)
  • Author(s): 森戸里衣子、橋本潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 90-91
• [Journal Article] 指尖容積脈波の2次微分波と上腕-足首間脈波伝播速度の規定因子 : 大迫研究 (2007)
  • Author(s): 橋本潤一郎
  • Journal Title: Arterial Stiffness 11 Pages: 80-81
• [Journal Article] Monitoring of antihypertensive therapy for reduction in left ventricular mass (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Journal Title: Am J Hypertens 20 Pages: 1229-1233
  • Peer Reviewed
• [Journal Article] Indices of pulse wave analysis are better predictors of left ventricular mass reduction than cuff pressure (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Journal Title: Am J Hypertens 20 Pages: 378-384
  • Peer Reviewed
• [Journal Article] Mechanical factors in arterial aging: a clinical perspective (2007)
  • Author(s): Michael F. O'Rourke, Junichiro Hashimoto
  • Journal Title: J Am Coll Cardiol 50 Pages: 1-13
  • Peer Reviewed
• [Journal Article] Incorporating self-blood pressure measurements at home in the guideline from the Ohasama study (2007)
  • Author(s): Takayoshi Ohkubo, Junichiro Hashimoto, et. al.
  • Journal Title: Blood Press Monitor 12 Pages: 407-409
  • Peer Reviewed
• [Journal Article] Factors affecting heart rate as measured at home among treated hypertensive patients: the Japan Home versus Office blood pressure Measurement Evaluation (J-HOME) Study (2007)
  • Author(s): Rie Komai, Junichiro Hashimoto, et. al.
  • Journal Title: Hypertens Res 30 Pages: 1051-1057
  • NAID: 10021259876
  • Peer Reviewed
• [Journal Article] Stroke risk in systolic and combined systolic and diastolic hypertension determined using ambulatory blood pressure: the Ohasama study (2007)
  • Author(s): Ryusuke Inoue, Junichiro Hashimoto, et. al.
  • Journal Title: Am J Hypertens 20 Pages: 1125-1131
  • Peer Reviewed
• [Journal Article] Control of home heart rate and home blood pressure levels in treated patients with hypertension: the J-HOME study (2007)
  • Author(s): Take Obara, Junichiro Hashimoto, et. al.
  • Journal Title: Blood Press Monitor 12 Pages: 289-295
  • Peer Reviewed
• [Journal Article] Ambulatory blood pressure, blood pressure variability and the prevalence of carotid artery alteration: the Ohasama study (2007)
  • Author(s): Yoriko Shintani, Junichiro Hashimoto, et. al.
  • Journal Title: J Hypertens 25 Pages: 1704-1710
  • Peer Reviewed
• [Journal Article] Kidney function as a risk factor for first symptomatic stroke events in a general Japanese population: the Ohasama study (2007)
  • Author(s): Masaaki Nakayama, Junichiro Hashimoto, et. al.
  • Journal Title: Nephrol Dial Transplant 22 Pages: 1910-1915
  • Peer Reviewed
• [Journal Article] Ambulatory arterial stiffness index and 24-hour ambulatory pulse pressure as predictors of mortality in Ohasama, Japan (2007)
  • Author(s): Masahiro Kikuya, Junichiro Hashimoto, et. al.
  • Journal Title: Stroke 38 Pages: 1161-1166
  • Peer Reviewed
• [Journal Article] Reproducibility of nocturnal blood pressure assessed by self-measurement of blood pressure at home (2007)
  • Author(s): Keiko Hosohata, Junichiro Hashimoto, et. al.
  • Journal Title: Hypertens Res 30 Pages: 707-712
  • NAID: 10019810416
  • Peer Reviewed
• [Journal Article] Plasma fibrinogen, ambulatory blood pressure, and silent cerebrovascular lesions: the Ohasama study (2007)
  • Author(s): Yoko Aono, Junichiro Hashimoto, et. al.
  • Journal Title: Arterioscler Thromb Vasc Biol 27 Pages: 963-968
  • NAID: 120003728009
  • Peer Reviewed
• [Journal Article] Detection of carotid atherosclerosis in individuals with masked hypertension and white-coat hypertension by self-measured blood pressure at home: the Ohasama study (2007)
  • Author(s): Azusa Hara, Junichiro Hashimoto, et. al.
  • Journal Title: J Hypertens 25 Pages: 321-327
  • Peer Reviewed
• [Journal Article] Progress report on The Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study: status at February 2004 (2007)
  • Author(s): Keiko Hosohata, Junichiro Hashimoto, et. al.
  • Journal Title: Clin Exp Hypertens 29 Pages: 69-81
  • Peer Reviewed
• [Journal Article] Circadian variation of the myocardial ischemic threshold in patients with ischemic heart disease (2007)
  • Author(s): Eiji Ino-Oka, Junichiro Hashimoto, et. al.
  • Journal Title: Clin Exp Hypertens 29 Pages: 3-12
  • Peer Reviewed
• [Journal Article] AIと動脈硬化リスク (2007)
  • Author(s): 橋本 潤一郎
  • Journal Title: 血圧 14 Pages: 49-54
• [Journal Article] 脈波分析の指標はカフ血圧よりも優れた左室重量減少の予測因子である (2007)
  • Author(s): 橋本 潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 70-71
• [Journal Article] 最高血圧は末梢ほど高いはずですが、HEM-9000AIでの測定で、中心血圧が上腕血圧より高い場合があるのはなぜでしょうか? (2007)
  • Author(s): 橋本 潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 106-106
• [Journal Article] 動脈壁硬化と心電図上左室肥大の関係:大迫研究 (2007)
  • Author(s): 森戸 里衣子、橋本 潤一郎
  • Journal Title: Arterial Stiffness 12 Pages: 90-91
• [Journal Article] 指尖容積脈波の2次微分波と上腕-足首間脈波伝播速度の規定因子:大迫研究 (2007)
  • Author(s): 橋本 潤一郎
  • Journal Title: Arterial Stiffness 11 Pages: 80-81
• [Journal Article] 二次性高血圧を疑ったときの診断手順 腎血管性高血圧 (2007)
  • Author(s): 石川智史、橋本潤一郎、他
  • Journal Title: Heart View 11 Pages: 351-357
• [Journal Article] 家庭血圧測定の指針とその臨床応用 (2007)
  • Author(s): 今井潤、橋本潤一郎、他
  • Journal Title: 日本内科学会雑誌 96 Pages: 86-93
• [Journal Article] 早朝高血圧患者におけるオルメサルタンとアムロジピンの薬効比較 (2007)
  • Author(s): 佐藤 茜、橋本 潤一郎、他
  • Journal Title: 臨床高血圧 13 Pages: 199-207
• [Journal Article] 家庭血圧測定に基づくフェノフィブラートの降圧効果評価 (2007)
  • Author(s): 石川 智史、橋本 潤一郎、他
  • Journal Title: Ther Res 28 Pages: 1853-1862
• [Journal Article] ACE阻害薬塩酸イミダプリルの早朝家庭血圧に及ぼす影響 (2007)
  • Author(s): 柴崎 貴子、橋本 潤一郎、他
  • Journal Title: 血圧 14 Pages: 99-104
• [Journal Article] 家庭血圧にもとづく選択的AT1受容体拮抗薬オルメサルタンの臨床的評価 (2007)
  • Author(s): 井上 奈緒、橋本 潤一郎、他
  • Journal Title: 血圧 14 Pages: 205-212
• [Presentation] 中心血圧を用いた薬効評価 (2009)
  • Author(s): 橋本潤一郎
  • Organizer: 第73回日本循環器学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-03-22
• [Presentation] Efficacy of low-dose losartan/hydrochlorothiazide combination versus high-dose angiotensin receptor blocker monotherapy on central blood pressure : J-HOME-AI multicenter randomized trial (2009)
  • Author(s): Junichiro Hashimoto
  • Organizer: 第73回日本循環器学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-03-22
• [Presentation] Losartan/HCTZ is more effective than titration to maximum-dose ARBs for uncontrolled hypertension in multi-center randomized controlled study : the J-HOME-AI study (2009)
  • Author(s): Hirohito Metoki, Junichiro Hashimoto
  • Organizer: 第73回日本循環器学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-03-21
• [Presentation] When and how should we use central BP in clinical hypertension? Report from ABC-J Study (2009)
  • Author(s): Katsuhiko Kohara, Junichiro Hashimoto, et.al.
  • Organizer: 第73回日本循環器学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-03-21
• [Presentation] 中心血圧からみた動脈-心臓連関 (2009)
  • Author(s): 橋本潤一郎
  • Organizer: 血管障害フォーラム2009
  • Place of Presentation: 東京
  • Year and Date: 2009-01-19
• [Presentation] 第31回日本高血圧学会トピック報告 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第9回AIの会
  • Place of Presentation: 京都
  • Year and Date: 2008-11-30
• [Presentation] 自由行動下心拍短期変動と家庭心拍日間変動の規定要因に関する検討 : 大迫研究 (2008)
  • Author(s): 後ノ上健太, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-11
• [Presentation] (プロ)レニン受容体遺伝子多型と高血圧性臓器障害との関連の検討 : 大迫研究 (2008)
  • Author(s): 廣瀬卓男、橋本潤一郎、他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] 家庭血圧を用いた高血圧発症予測遺伝子多型の同定 : 大迫研究における12年の追跡から (2008)
  • Author(s): 渡邉悠美子, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] 家庭血圧導入の医療経済学的評価 : 外来血圧コントロール良好高血圧患者における検討 (2008)
  • Author(s): 田巻佑一郎, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] 高血圧治療ガイドラインに基づいたリスク分類 : 大迫研究 (2008)
  • Author(s): 浅山敬, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] 非飲酒者における就寝前家庭血圧の有用性 : 大迫研究 (2008)
  • Author(s): 浅山敬, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] わが国の家庭血圧測定の現状と変化 : 外来患者の実践と意識"家庭血圧測定の現状に関する調査研究-2" (2008)
  • Author(s): 大久保孝義, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-10
• [Presentation] 脳腎連関 : 微小血管障害に対する大血管スティフネスの影響 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-09
• [Presentation] AASIおよび24時間脈圧の再現性・予後予測能-全血圧値および一部の血圧値による検討 : 大迫研究 (2008)
  • Author(s): 菊谷昌浩, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-09
• [Presentation] 血清マグネシウム濃度・24時間自由行動下血圧と頚動脈硬化指標との関連 : 大迫研究 (2008)
  • Author(s): 橋本貴尚, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-09
• [Presentation] 家庭ダブルプロダクトと予後〜大迫研究より (2008)
  • Author(s): 井上隆輔, 橋本潤一郎, 他
  • Organizer: 第31回日本高血圧学会総会
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-09
• [Presentation] Cerebro-renal connection: Involvement of large artery stiffening in microvascular organ damage (2008)
  • Author(s): Junichiro Hashimoto
  • Organizer: 62nd High Blood Pressure Research Conference of American Heart Association
  • Place of Presentation: Atlanta
  • Year and Date: 2008-09-18
• [Presentation] Cerebro-renal connection : Involvement of large artery stiffening in microvascular organ damage (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Organizer: 62nd High Blood Pressure Research Conference of American Heart Association
  • Place of Presentation: Atlanta (アメリカ)
  • Year and Date: 2008-09-18
• [Presentation] 高血圧性左室肥大と中心血圧の関連 : 動脈波反射の影響 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第57回日本心臓病学会
  • Place of Presentation: 東京
  • Year and Date: 2008-09-09
• [Presentation] 高血圧性左室肥大と中心血圧の関連 : 動脈波反射の影響 (2008)
  • Author(s): 橋本潤一郎, 他
  • Organizer: 第56回日本心臓病学会
  • Place of Presentation: 東京
  • Year and Date: 2008-09-09
• [Presentation] 中心血圧と薬効評価 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第9回国際統合医学会
  • Place of Presentation: 東京
  • Year and Date: 2008-07-12
• [Presentation] Multi-center cross-sectional study to characterize antihypertensive treatments in terms of central blood pressure evaluated by radial artery pulse waveform - antihypertenves and blood pressure of central artery study in Japan (2008)
  • Author(s): Junichiro Hashimoto
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin
  • Year and Date: 2008-06-18
• [Presentation] Multi-center cross-sectional study to characterize antihypertensive treatments in terms of central blood pressure evaluated by radial artery pulse waveform - antihypertenves and blood pressure of central artery study in Japan (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin (ドイツ)
  • Year and Date: 2008-06-18
• [Presentation] Ambulatory versus home blood pressure-Which is more closely associated with silent cerebrovascular lesions and carotid atherosclerosis? (2008)
  • Author(s): Azusa Hara, Junichiro Hashimoto, et.al.
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin (ドイツ)
  • Year and Date: 2008-06-17
• [Presentation] Current status of home blood pressure measurement in Japan (2008)
  • Author(s): Taku Obara, Junichiro Hashimoto, et.al.
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin (ドイツ)
  • Year and Date: 2008-06-17
• [Presentation] Evening home blood pressure predicts stroke risk independent of morning home blood pressure among non-drinkers (2008)
  • Author(s): Kei Asayama, Junichiro Hashimoto, et.al.
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin (ドイツ)
  • Year and Date: 2008-06-16
• [Presentation] Cost-effectiveness of the introduction of home blood pressure measurement in patients with office hypertension (2008)
  • Author(s): Hidefumi Fukunaga, Junichiro Hashimoto, et.al.
  • Organizer: 22nd scientific meeting of International Society of Hypertension
  • Place of Presentation: Berlin (ドイツ)
  • Year and Date: 2008-06-16
• [Presentation] 降圧治療とventricular-vascular interaction : 末梢動脈圧波反射の減少を介した左室肥大の退縮 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第6回臨床血圧脈波研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-06-07
• [Presentation] 脳腎連関 : 微小血管障害に対する大血管スティフネスの影響 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第6回臨床血圧脈波研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-06-07
• [Presentation] J-HOME AI研究中間報告 (2008)
  • Author(s): 橋本潤一郎
  • Organizer: 第2回J-HOME AI研究会
  • Place of Presentation: 仙台
  • Year and Date: 2008-06-03
• [Presentation] Prediction of left ventricular mass reduction with antihypertensive therapy from harmonic content of the aortic pressure waveform (2008)
  • Author(s): Junichiro Hashimoto
  • Organizer: 23rd Scientific meeting of American Society of Hypertension
  • Place of Presentation: New Orleans
  • Year and Date: 2008-05-14
• [Presentation] Prediction of left ventricular mass reduction with antihypertensive therapy from harmonic content of the aortic pressure waveform (2008)
  • Author(s): Junichiro Hashimoto, et.al.
  • Organizer: 23rd Scientific meeting of American Society of Hypertension
  • Place of Presentation: New Orleans (アメリカ)
  • Year and Date: 2008-05-14
• [Presentation] Central blood pressure and augmentation index for better management of cardiovascular disease (2008)
  • Author(s): Junichiro Hashimoto
  • Organizer: Singapore Disease Management Conference
  • Place of Presentation: Singapore
  • Year and Date: 2008-05-08
• [Presentation] Central blood pressure and augmentation index for better management of cardiovascular disease (2008)
  • Author(s): Junichiro Hashimoto
  • Organizer: Singapore Disease Management Conference
  • Place of Presentation: Singapore(シンガポール)
  • Year and Date: 2008-05-08
• [Presentation] 大動脈硬化指標と微量アルブミン尿との関連 (2007)
  • Author(s): 石川智史、橋本潤一郎
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 宜野湾市
  • Year and Date: 2007-10-27
• [Presentation] 動脈壁硬化と無症候性脳血管障害との関連 (2007)
  • Author(s): 森戸里衣子、橋本潤一郎
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 宜野湾市
  • Year and Date: 2007-10-27
• [Presentation] 降圧治療に伴う左室重量退縮における動脈波反射の役割 : 定量的反射波分離法を用いた検討 (2007)
  • Author(s): 橋本潤一郎
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 宜野湾市
  • Year and Date: 2007-10-27
• [Presentation] 降圧治療に伴う左室重量退縮における動脈波反射の役割: 定量的反射波分離法を用いた検討 (2007)
  • Author(s): 橋本 潤一郎、他
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 沖縄コンベンションセンター(宜野湾市)
  • Year and Date: 2007-10-27
• [Presentation] 動脈壁硬化と無症候性脳血管障害との関連 (2007)
  • Author(s): 森戸 里衣子、橋本 潤一郎、他
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 沖縄コンベンションセンター(宜野湾市)
  • Year and Date: 2007-10-27
• [Presentation] 大動脈硬化指標と微量アルブミン尿との関連 (2007)
  • Author(s): 石川 智史、橋本 潤一郎、他
  • Organizer: 第30回日本高血圧学会総会
  • Place of Presentation: 沖縄コンベンションセンター(宜野湾市)
  • Year and Date: 2007-10-27
• [Presentation] Monitoring of antihypertensive treatment for left ventricular mass regression (2007)
  • Author(s): Junichiro Hashimoto
  • Organizer: オーストラリア・ニュージーランド心臓学会2007
  • Place of Presentation: クライストチャーチ
  • Year and Date: 2007-08-10
• [Presentation] Monitoring of antihypertensive treatment for left ventricular mass regression (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Organizer: オーストラリア・ニュージーランド心臓学会2007
  • Place of Presentation: クライストチャーチ会議場(クライストチャーチ)
  • Year and Date: 2007-08-10
• [Presentation] Different role of wave reflection magnitude and timing in left ventricular mass reduction during antihypertensive treatment (2007)
  • Author(s): Junichiro Hashimoto
  • Organizer: 第16回ヨーロッパ高血圧学会
  • Place of Presentation: ミラノ
  • Year and Date: 2007-06-17
• [Presentation] Different role of wave reflection magnitude and timing in left ventricular mass reduction during antihypertensive treatment (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Organizer: 第16回ヨーロッパ高血圧学会
  • Place of Presentation: フィエラミラノ会議場(ミラノ)
  • Year and Date: 2007-06-17
• [Presentation] Is pulse wave analysis superior to home blood pressure measurement in predicting antihypertensive treatment-induced regression of left ventricular mass? (2007)
  • Author(s): Junichiro Hashimoto
  • Organizer: 第22回アメリカ高血圧学会
  • Place of Presentation: シカゴ
  • Year and Date: 2007-05-19
• [Presentation] Association between wasted pressure energy and left ventricular hypertrophy : Influence of arterial wave reflection (2007)
  • Author(s): Junichiro Hashimoto
  • Organizer: 第22回アメリカ高血圧学会
  • Place of Presentation: シカゴ
  • Year and Date: 2007-05-19
• [Presentation] Association between wasted pressure energy and left ventricular hypertrophy:Influence of arterial wave reflection (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Organizer: 第22回アメリカ高血圧学会
  • Place of Presentation: ハイアット・リージェンシーホテル(シカゴ)
  • Year and Date: 2007-05-19
• [Presentation] Is pulse wave analysis superior to home blood pressure measurement in predicting antihypertensive treatment-induced regression of left ventricular mass? (2007)
  • Author(s): Junichiro Hashimoto, et. al.
  • Organizer: 第22回アメリカ高血圧学会
  • Place of Presentation: ハイアット・リージェンシーホテル(シカゴ)
  • Year and Date: 2007-05-19
• [Book] The aorta : Structure function, dysfunction, and diseases (2009)
  • Author(s): Junichiro Hashimoto, Michael F. O'Rourke
  • Publisher: Physiology-basic concepts and regulation of aortic function
• [Book] The aorta : Structure, function, dysfunction, and diseases (2009)
  • Author(s): Junichiro Hashimoto, Michael F. O'Rourke
  • Publisher: Aorta peripheral arteries interrelationship
• [Book] Physiology - basic concepts and regulation of aortic function. The aorta : Structure, function, dysfunction, and diseases (2009)
  • Author(s): Junichiro Hashimoto, et.al.
  • Total Pages: 350
  • Publisher: UK : Informa Healthcare
• [Book] Aorta - peripheral arteries interrelationship. The aorta : Structure, function, dysfunction, and diseases (2009)
  • Author(s): Junichiro Hashimoto, et.al.
  • Total Pages: 350
  • Publisher: UK : Informa Healthcare
• [Book] 心機能と動脈スティフネスの関連 (2008)
  • Author(s): 橋本潤一郎
  • Publisher: 新しい血圧測定と脈波解析マニュアル、メジカルビュー社
• [Book] PWVおよび中心血圧(AI)の臨床への応用.高血圧診療への応用 (2008)
  • Author(s): 橋本潤一郎
  • Publisher: 新しい血圧測定と脈波解析マニュアル、メジカルビュー社
• [Book] 中心血圧、AIの予後予測能 (2008)
  • Author(s): 橋本潤一郎
  • Publisher: 新しい血圧測定と脈波解析マニュアル、メジカルビュー社
• [Book] PWVおよび中心血圧(AI)からみた予防医学と生活習慣. 検診への応用 (2008)
  • Author(s): 石川智史、橋本潤一郎、今井潤
  • Publisher: 新しい血圧測定と脈波解析マニュアル、メジカルビュー社
• [Book] 心機能と動脈スティフネスの関連. 新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本潤一郎
  • Publisher: メジカルビュー社
• [Book] PWVおよび中心血圧(AI)の臨床への応用. 高血圧診療への応用. 新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本潤一郎
  • Publisher: メジカルビュー社
• [Book] 中心血圧、AIの予後予測能. 新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本潤一郎
  • Publisher: メジカルビュー社
• [Book] PWVおよび中心血圧(AI)からみた予防医学と生活習慣. 検診への応用. 新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 石川智史、橋本潤一郎、今井潤
  • Publisher: メジカルビュー社
• [Book] Physiology-basic concepts and regulation of aortic function. The aorta: Structure, function, dysfunction, and diseases (2008)
  • Author(s): Junichiro Hashimoto, et. al.
  • Publisher: UK: Informa Healthcare(In press)
• [Book] Aorta-peripheral arteries interrelationship. The aorta: Structure, function, dysfunction, and diseases (2008)
  • Author(s): Junichiro Hashimoto, et. al.
  • Publisher: UK: Informa Healthcare(In press)
• [Book] 心機能と動脈スティフネスの関連.新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本 潤一郎
  • Publisher: メジカルビュー社(In press)
• [Book] PWVおよび中心血圧(AI)の臨床への応用, 高血圧診療への応用.新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本 潤一郎
  • Publisher: メジカルビュー社(In press)
• [Book] 中心血圧、AIの予後予測能.新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 橋本 潤一郎
  • Publisher: メジカルビュー社(In press)
• [Book] PWVおよび中心血圧(AI)からみた予防医学と生活習慣.検診への応用.新しい血圧測定と脈波解析マニュアル (2008)
  • Author(s): 石川 智史、橋本 潤一郎、他
  • Publisher: メジカルビュー社(In press)
• [Remarks]
  • URL: http://db.tohoku.ac.jp/whois/detail/f797c313ce8b498c1a44ab2e53edb2a9.html
• [Remarks]
  • URL: http://db.tohoku.ac.jp/whois/detail/f797c313ce8b498cla44ab2e53edb2a9.html