Development of dendritic cell vaccine modified with a ligand of NKT cells against tuberculosis
| Project/Area Number |
19590888
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
SUDA Takafumi Hamamatsu University School of Medicine, 医学部, 助教 (30291397)
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| Co-Investigator(Kenkyū-buntansha) |
NAGATA Toshi 浜松医科大学, 医学部, 教授 (90275024)
CHIDA Kingo 浜松医科大学, 医学部, 准教授 (40197611)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 樹状細胞 / ワクチン / 結核 / NKT細胞 / リステリア |
|---|
| Research Abstract |
未だ有効なワクチンがない結核菌を含む細胞内寄生菌感染症に対し、NKT細胞のリガンドであるαガラクトシルセラミドを用いて極めて強い感染防御能を誘導する樹状細胞ワクチンの開発に成功した。
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Report
(3 results)
Research Products
(13 results)
