| Project/Area Number |
19591207
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Pediatrics
|
|---|
| Research Institution | Tottori University |
|---|
Principal Investigator |
HANAKI Keiichi Tottori University, 医学部, 教授 (20238041)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NAGAISHI Junichi 鳥取大学, 医学部附属病院, 講師 (90346354)
NAGATA Ikuo 鳥取大学, 医学部, 准教授 (50252846)
KANZAKI Susumu 鳥取大学, 医学部, 教授 (90224873)
KINOSHITA Tomoe 鳥取大学, 医学部附属病院, 助教 (80444636)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | メタボリックシンドローム / 小児肥満 / 遺伝性肥満 / アディポネクチン / 子宮内発育不全 / 糖尿病 / シグナル伝達 |
|---|
| Research Abstract |
The aim of this study was to elucidate the mechanism by which the metabolic syndrome developed, especially in Alstroem syndrome, a hereditary obesity inevitably developing the metabolic syndrome. Several findings were obtained focusing on the insulin/IGF-1 action in the Alstroem syndrome, a relationship between SNPs for obesity-related genes and blood chemistry, and a relationship between high-molecular adiponectin and intra/extra uterine growth.
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