Clinical value of F-18 FDG PET in patients with connective tissue diseases

• Project/Area Number: 19591420
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kagawa University
• Principal Investigator: NISHIYAMA Yoshihiro Kagawa University, 医学部, 教授 (50263900)
• Co-Investigator(Kenkyū-buntansha): YAMAMOTO Yuka 香川大学, 医学部附属病院, 講師 (30335872) ; DOBASHI Hiroaki 香川大学, 医学部, 助教 (50380176) ; 大川 元臣 香川大学, 医学部, 教授 (70028629)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: F-18 FDG / PET検査 / 膠原病 / 活動性評価 / 治療効果判定 / F-18FDG

Research Abstract

Connective tissue diseases represent a heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lung. F-18 FDG PET is widely used in oncology but may also be valuable in patients with infections or inflammatory diseases. The purpose of this study is to assess the clinical value of F-18 FDG PET in patients with connective tissue diseases. Our experience demonstrates that F-18 FDG PET is a unique imaging technique for assessing the metabolic activity throughout the body in connective tissue diseases. The technique appears to be a promising imaging modality for the detection of coexistent neoplastic diseases and other autoimmune disorders.

Research Products

• [Journal Article] Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index (2009)
  • Author(s): Masugata Hisashi、Nishiyama Yoshihiro、ほか12人11番目
  • Journal Title: Tohoku J Exp Med 219(in press) Pages: 101-105
  • NAID: 10025534411
  • Peer Reviewed
• [Journal Article] Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index (2009)
  • Author(s): Masugata Hisashi
  • Journal Title: Tohoku J Exp Med 219 Pages: 101-105
  • Peer Reviewed
• [Journal Article] F-18 FDG PET findings of Takayasu arteritis before and after immunosuppressive therapy (2008)
  • Author(s): Iwabu Masako、Nishiyama Yoshihiro、ほか4人6番目
  • Journal Title: Clin Nucl Med 339 Pages: 872-873
  • Peer Reviewed
• [Journal Article] F-18 FDG PET findings of Takayasu arteritis before and after immunosuppressive therapy (2008)
  • Author(s): Iwabu Masako
  • Journal Title: Clinical Nuclear Medicine 33 Pages: 872-873
  • Peer Reviewed
• [Journal Article] F-18 fluorodeoxyglucose positron emission tomography imaging in a case of relapsing polychondritis (2007)
  • Author(s): Nishiyama Yoshihiro、ほか5人1番目
  • Journal Title: J Comput Assist Tomogr 31 Pages: 381-383
  • Peer Reviewed
• [Journal Article] ^<18>F-FDG PET imaging in a case of relapsing polychondritis (2007)
  • Author(s): Nishiyama Yoshihiro
  • Journal Title: Journal of Computer Assisted Tomography 31 Pages: 381-383
  • Peer Reviewed
• [Presentation] 膠原病症例におけるF-18 FDG PET検査の有用性 (2010)
  • Author(s): 山本由佳
  • Organizer: 第69回日本医学放射線学会
  • Place of Presentation: 横浜
• [Presentation] FDG PET imaging in Takayasu aortitis before and after treatment (2008)
  • Author(s): Nishiyama Yoshihiro
  • Organizer: 55th Annual Meeting of the Society of Nuclear Medicine
  • Place of Presentation: New Orleans U. S. A
  • Year and Date: 2008-06-17
• [Presentation] FDG PET imaging in Takayasu aortitis before and after treatment (2008)
  • Author(s): Nishiyama Yoshihiro
  • Organizer: 55th Annual Meeting of the Society of Nuclear Medicine
  • Place of Presentation: New Orleans(U.S. A)
• [Presentation] Diagnosis and monitoring of Takayasu aortitis:value of FDGPET (2007)
  • Author(s): Nishiyama Yoshihiro
  • Organizer: 93rd Scientific Assembly and Annual Meeting Radiological Society of North America
  • Place of Presentation: Chicago
  • Year and Date: 2007-11-25
• [Presentation] Diagnosis and monitoring of Takayasu aortitis: value of FDG PET (2007)
  • Author(s): Nishiyama Yoshihiro
  • Organizer: 93rd Scientific Assembly and Annual Meeting Radiological Society of North America
  • Place of Presentation: Chicago (U.S. A)
• [Presentation] Clinical Value of FDG PET in patients with connective tissue disease (2006)
  • Author(s): Nishiyama Yoshihiro
  • Organizer: 92nd Scientific Assembly and Annual Meeting Radiological Society of North America
  • Place of Presentation: Chicago (U.S. A)