• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of a method of prediction for tumor cell radiosensitivity using Premature Chromosome Condensation

Research Project

Project/Area Number 19591454
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionNiigata University

Principal Investigator

SASAI Keisuke  Niigata University, 医歯学系, 教授 (20225858)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords放射線感受性 / 未成熟染色体凝集 / HVJ-envelope / HVJ envelope / 染色体障害 / HVJ Envelope
Research Abstract

センダイウイルスエンベロープ(HVJ-E)を用いて、未成熟染色体凝集(PCC)を簡便に誘導できた。放射線照射24時間後、すなわちDNA修復がほぼ完全に終了した時点で誘導したPCCから第4染色体断片数を測定し、さらに照射前の第4染色体数で補正したところ、断片数と細胞生存率の関係は、従来の報告とほぼ一致した。HVJ-Eを用いる本方法でも放射線感受性が測定できることが示された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (5 results)

All 2009 2008 2007

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Diagnostic limitations of 10 mm thickness single-slice computed tomography for patients with suspected appendicitis2008

    • Author(s)
      Kaidu M, Oyamatu M, Sato K, Saitou A, Yamamoto S, Yoshimura N, Sasai K
    • Journal Title

      Radiat Med 26(2)

      Pages: 63-69

    • NAID

      10024137890

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic computed tomography findings of malignant intraductal papillary mucinous tumor compared with invasive ductal adenocarcinoma2007

    • Author(s)
      Ozaki T, Kamura T, Ajioka Y, Shirai Y, Kurosaki I, Yamamoto S, Sasai K
    • Journal Title

      Radiat Med 25(9)

      Pages: 446-452

    • NAID

      10019969671

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] PCC-FISH 法による放射線感受性予測法の改良2009

    • Author(s)
      後藤直樹、高橋俊博、笹井啓資
    • Organizer
      第11回癌治療増感研究シンポジウム
    • Place of Presentation
      奈良県奈良市
    • Year and Date
      2009-02-15
    • Related Report
      2008 Final Research Report
  • [Presentation] PCC-FISH法による放射線感受性予測法の改良2009

    • Author(s)
      後藤直樹, 高橋俊博, 笹井啓資
    • Organizer
      第11回癌治療増感研究シンポジウム
    • Place of Presentation
      奈良県奈良市
    • Year and Date
      2009-02-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Chemoradiotherapy using low-dose protracted infusion of 5-FU alone is as effective as 5-FU combined with cisplatin for advanced esophageal cancer2007

    • Author(s)
      SASAMOTO R, TSUCHIDA E, ABE E, FUKUDA T, KAWAGUCHI G, SASAI K
    • Organizer
      49th Annual Meeting of the ASTRO
    • Place of Presentation
      Los Angeles, CA, USA
    • Related Report
      2008 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi