Intensity modulated radiotherapy using a physical filter to track the targeted migration

• Project/Area Number: 19591465
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Keio University
• Principal Investigator: KUTSUKI Shoji Keio University, 医学部, 講師 (00234443)
• Co-Investigator(Kenkyū-buntansha): KUNIEDA Etsuo 慶應義塾大学, 医学部, 共同研究員 (70170008) ; 川瀬 貴嗣 慶應義塾大学, 医学部, 助教 (80306795)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: IMRT / 固体物理フィルター / 腫瘍追従装置 / 4次元CT

Research Abstract

The purpose of this study was to investigate the advantage of our original solid-filter-based IMRT method. We developed a two-dimensional drive device for the solid-filter using motor-driven actuators. Experiments revealed that our system could drive the filter precisely according to the periodical and geometrical data of the lung tumor obtained from a 4D CT acquisition.

Research Products

• [Journal Article] 胃癌に対する放射線治療 (2009)
  • Author(s): 沓木章二, (他8名)
  • Journal Title: 東京都医師会雑誌 62 Pages: 450-452
  • Peer Reviewed
• [Journal Article] Stereotactic body radiotherapy for primary lung cancer at a dose of 50 Gy total in five fractions to the periphery of the planning target volume calculated using a superposition algorithm (2009)
  • Author(s): Takeda A, Sanuki N, Kunieda E, (他5名)
  • Journal Title: Int J Radiat Oncol Biol Phys 73 Pages: 442-448
• [Journal Article] Dose distribution analysis in stereotactic body radiotherapy using dynamic conformal multiple arc therapy (2009)
  • Author(s): Takeda A, Kunieda E, (他9名)
  • Journal Title: Int J Radiat Oncol Biol Phys 74 Pages: 363-369
  • Peer Reviewed
• [Journal Article] The reproducibility of a HeadFix relocatable fixation system: analysis using the stereotactic coordinates of bilateral incus and the top of the crista galli obtained from a serial CT scan (2009)
  • Author(s): Kunieda E, (他6名)
  • Journal Title: Phys Med Biol 54
  • Peer Reviewed
• [Journal Article] 胃癌に対する放射線治療 (2009)
  • Author(s): 沓木章二
  • Journal Title: 東京都医師会雑誌 62 Pages: 450-452
  • Peer Reviewed
• [Journal Article] Combination of abducens nerve palsy and ipsilateral postganglionic Horner syndrome as an initial manifestation of uterine cervical cancer (2009)
  • Author(s): Tsuda, H
  • Journal Title: Intern Med 48 Pages: 1457-1460
  • Peer Reviewed
• [Journal Article] The reproducibility of a HeadFix relocatable fixation system : analysis using the stereotactic coordinates of bilateral incus and the top of the crista galli obtained from a serial CT scan (2009)
  • Author(s): Kunieda, E
  • Journal Title: Phys Med Biol 54
  • Peer Reviewed
• [Journal Article] 婦人科がん診療のリスクマネージメント】放射線療法の問題点晩期有害事象 (2008)
  • Author(s): 藤井多久磨, 仲村勝, 沓木章二, (他7名)
  • Journal Title: 産婦人科の実際 57 Pages: 1873-1879
  • Peer Reviewed
• [Journal Article] 当院での肺定位放射線治療の方法と成績 (2008)
  • Author(s): 柏山史穂, 沓木章二, (他6名)
  • Journal Title: 共済医報 57 Pages: 99-99
  • Peer Reviewed
• [Journal Article] リニアックグラフィーの画像処理パラメーターの検討 (2008)
  • Author(s): 安田武史, 上窪純史, 沓木章二, (他5名)
  • Journal Title: 共済医報 Pages: 125-125
  • Peer Reviewed
• [Journal Article] SRT時のSlow Scan CTによる治療計画の問題点 (2008)
  • Author(s): 上窪純史, 安田武史, 富田大介, 奈良由紀夫, 柏山史穂, 沓木章二
  • Journal Title: 共済医報 57 Pages: 125-125
  • Peer Reviewed
• [Journal Article] 高精度放射線治療における呼吸移動への対応-AAPM Task Group 76報告を中心に (2008)
  • Author(s): 国枝悦夫, 奥洋平, 橋本慎平
  • Journal Title: 臨床放射線 53 Pages: 381-385
  • Peer Reviewed
• [Journal Article] 放射線治療の最前線高精度放射線治療 (2008)
  • Author(s): 国枝悦夫, 久保敦司
  • Journal Title: クリニシアン 55 Pages: 650-656
  • Peer Reviewed
• [Journal Article] Patterns of local recurrence after intraoperative radiotherapy for advanced neuroblastoma (2008)
  • Author(s): Kunieda E, Hirobe S, Kaneko T, (他3名)
  • Journal Title: Jpn J Clin Oncol 38 Pages: 562-566
  • Peer Reviewed
• [Journal Article] Accumulation of gallium-67 within mature and immature teratoma in pediatric patients:investigation for the uptake mechanism (2008)
  • Author(s): Kunieda E, Hara H, Morikawa Y, (他3名)
  • Journal Title: Ann Nucl Med 22 Pages: 207-213
  • Peer Reviewed
• [Journal Article] Variation of dose distribution of Stereo-tactic radiotherapy for small-volume lung tumors under different respiratory conditions (2008)
  • Author(s): Kunieda E, Deloar HM, Kishitani N, (他5名)
  • Journal Title: Phys Med 24 Pages: 204-211
  • Peer Reviewed
• [Journal Article] SRT時のSlow Scan CTによる治療計画の問題点 (2008)
  • Author(s): 上窪純史
  • Journal Title: 共済医報 57 Pages: 125-125
  • Peer Reviewed
• [Journal Article] 【婦人科がん診療のリスクマネージメント】放射線療法の問題点晩期有害事象 (2008)
  • Author(s): 藤井多久磨
  • Journal Title: 産婦人科の実際 57 Pages: 1873-1879
  • Peer Reviewed
• [Journal Article] Variation of dose distribution of stereotactic radiotherapy for small-volume lung tumors under different respiratory conditions (2008)
  • Author(s): E. Kunieda
  • Journal Title: Physica Medica (in printing)
  • Peer Reviewed
• [Journal Article] 子宮頸癌術後の放射線化学同時併用療法施行症例に関する検討 (2007)
  • Author(s): 仲村勝, 藤井多久磨, 村上功, 大野暁子, 中川博之, 岩田卓, 塚崎克己, 青木大輔, 沓木章二
  • Journal Title: 日本癌治療学会誌 42 Pages: 531-531
  • Peer Reviewed
• [Journal Article] Interface software for DOSXYZnrc Monte Carlo dose evaluation on a commercial radiation treatment planning system (2007)
  • Author(s): Kunieda E, Deloar HM, Takagi S, (他7名)
  • Journal Title: Radiat Med 25 Pages: 309-314
  • NAID: 10019726821
  • Peer Reviewed
• [Journal Article] Interface software for DOSXYZnrc Monte Carlo dose evaluation on a commercial radiation treatment planning system (2007)
  • Author(s): E. Kunieda
  • Journal Title: Radiat Med 25 Pages: 309-314
  • NAID: 10019726821
  • Peer Reviewed
• [Presentation] 前後方向照射における高エネルギーx線の距離の減弱について (2009)
  • Author(s): 荻谷敬二
  • Organizer: 日本放射線腫瘍学会第22回学術大会
  • Place of Presentation: 京都
  • Year and Date: 2009-11-18
• [Presentation] 外転神経麻痺と節後性 Horner 症候群を初発症状とした子宮頸癌 (2009)
  • Author(s): 津田浩昌
  • Organizer: 第47回日本神経眼科学会総会
  • Place of Presentation: 日経ホール(東京都)
  • Year and Date: 2009-11-14
• [Presentation] 複数台カメラを用いた放射線治療のための動き検出システムの開発 (2009)
  • Author(s): 間宮剛
  • Organizer: 第79回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2009-04-19
• [Presentation] Stereotactic Body Radiotherapy (SBRT) for Primary Lung Cancer at a Dose of 50 Gy per 5 Fractions to the Periphery of the Planning Target Volume (PTV) Calculated by a Superposition Algorithm (2008)
  • Author(s): Takeda A
  • Organizer: ASTRO 50th Annual Meeting
  • Place of Presentation: Boston
  • Year and Date: 2008-09-22
• [Presentation] Cone-Beam CT dataを用いた臓器移動による線量体積ヒストグラム変化の評価 (2008)
  • Author(s): 奥洋平
  • Organizer: 第18回日本高精度放射線外部照射研究会
  • Place of Presentation: 福岡
  • Year and Date: 2008-07-26
• [Presentation] 食道癌に対する化学放射線/放射線治療後の胸水、心嚢液貯留 (2008)
  • Author(s): 白石 悠
  • Organizer: 第67回日本医学放射線学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-04
• [Presentation] 補償フィルターIMRTでの線質硬化による深部量の変化 (2007)
  • Author(s): 橋本慎平
  • Organizer: 日本放射線腫瘍学会20回学術大会
  • Place of Presentation: 福岡
  • Year and Date: 2007-12-14
• [Presentation] 放射線治療患者患者情報共有システムの独自開発と運用状況について (2007)
  • Author(s): 青木 陽介
  • Organizer: 日本放射線腫瘍学会第20回学術大会
  • Place of Presentation: 福岡
  • Year and Date: 2007-12-14
• [Presentation] 補償フィルタIMRTでの線質硬化による深部量の変化 (2007)
  • Author(s): 橋本 慎平
  • Organizer: 日本放射線腫瘍学会第20回学術大会
  • Place of Presentation: 福岡
  • Year and Date: 2007-12-14
• [Presentation] Symptomatic Extrapulomnary Soft-Tissue Fibrosis Resulting From Hypofractionated Stereotactic Radiotherapy Pulmonary Nodular Lesion (2007)
  • Author(s): T. Kawase
  • Organizer: 49th Annual ASTRO Meeting
  • Place of Presentation: Los Angeles,U.S.A
  • Year and Date: 2007-10-28
• [Presentation] Monte Carlo modeling of stereotactic radiotherapy system for small lung tumors (2007)
  • Author(s): H. Deloar
  • Organizer: EPSM/ABEC2007
  • Place of Presentation: Fremantle, Western Australia
  • Year and Date: 2007-10-14
• [Presentation] An experimental converging stereotactic radiotherapy machine using Idlo-voltage narrow beam X-ray (2007)
  • Author(s): E. Kunieda
  • Organizer: he 5th Japan-US Cancere Therapy Symposium
  • Place of Presentation: 仙台
  • Year and Date: 2007-09-07
• [Presentation] 肺腫瘍に対する体幹部定位放射線治療(SBRT)時にLong scan time CTにて描出不能なintra-fractional organ motion error (2007)
  • Author(s): 青木 陽介
  • Organizer: 第16回日本高精度放射線外部照射研究会
  • Place of Presentation: 東京都千代田区
  • Year and Date: 2007-07-18
• [Presentation] 補償フィルターを用いたIMRTの初期経験 (2007)
  • Author(s): 菅原 章友
  • Organizer: 第66回日本医学放射線学会学術集会
  • Place of Presentation: 横浜
  • Year and Date: 2007-04-13
• [Presentation] 固体物理フィルタを用いたIMRTの品質管理 (2007)
  • Author(s): 奥 洋平
  • Organizer: 第93回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2007-04-13