| Project/Area Number |
19591493
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
General surgery
|
|---|
| Research Institution | Wakayama Medical University |
|---|
Principal Investigator |
IWAHASHI Makoto Wakayama Medical University, 医学部, 講師 (70244738)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YAMAUE Hiroki 和歌山県立医科大学, 医学部, 教授 (20191190)
NAKAMORI Mikihito 和歌山県立医科大学, 医学部, 講師 (10322372)
NAKAMURA Masaki 和歌山県立医科大学, 医学部, 助教 (80364090)
MATSUDA Kenji 和歌山県立医科大学, 医学部, 助教 (30398458)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 外科総論 / 胃癌 / IL-17 / IL-21 / 炎症 / 血管新生 / 癌浸潤 / 癌 / 外科 / 免疫 / 遺伝子 / サイトカイン |
|---|
| Research Abstract |
Expression of IL-17, IL-21 and IL-23 mRNA was found to be significantly up-regulated in tumor tissues compared with adjacent normal tissues. The expression level of IL-17 mRNA correlated with that of IL-21 and IL-23 mRNA in tumor tissue. The expression level of IL-17 mRNA in gastric tumors was associated with the depth of the tumors, suggesting that IL-17 obviously was related to tumor progression.
|
