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The establishment and analysis of new human lung cancer cell lines

Research Project

Project/Area Number 19591516
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionTokyo Medical University

Principal Investigator

NOMURA Masaharu  Tokyo Medical University, 医学部, 講師 (40424494)

Co-Investigator(Kenkyū-buntansha) 加藤 治文  東京医科大学, 医学部, 教授 (20074768)
平野 隆  東京医科大学, 医学部, 准教授 (30238381)
大平 達夫  東京医科大学, 医学部, 講師 (40317847)
Co-Investigator(Renkei-kenkyūsha) IKEDA Norihiko  東京医科大学, 医学部, 教授 (70246205)
OHIRA Tatsuo  東京医科大学, 医学部, 准教授 (40317847)
NISHIMURA Toshihide  東京医科大学, 医学部, 客員教授 (40366092)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywords肺癌 / 大細胞神経内分泌癌 / セルライン / マイクロアレイ / プロテオーム
Research Abstract

肺癌に関して、日本人由来の肺癌細胞株を樹立し、発現している遺伝子、蛋白質等を調べ、さらに実験などに利用し、最終的に肺癌の診断、治療に役立てる事がこの研究の最終的な目的である。私達は患者の癌組織から細胞株を計10 株樹立する事が出来た。その中の一つで特に悪性度の高い大細胞神経内分泌癌の細胞株に特異的な遺伝子及び蛋白質の発現を認めた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (5 results)

All 2009 2008

All Presentation (4 results) Patent(Industrial Property Rights) (1 results)

  • [Presentation] A cell line from LCNEC of the lung and its genetic and proteomic analysis2009

    • Author(s)
      MASAHARU NOMURA
    • Place of Presentation
      米国(Denver)
    • Year and Date
      2009-04-22
    • Related Report
      2008 Final Research Report
  • [Presentation] A cell line from LCNEC of the lung and its genetic and proteomic analysis2009

    • Author(s)
      MASAHARU NOMURA
    • Organizer
      米国癌学会
    • Place of Presentation
      デンバー
    • Year and Date
      2009-04-22
    • Related Report
      2008 Annual Research Report
  • [Presentation] 肺LCNEC 細胞株の樹立と特性2008

    • Author(s)
      野村将春
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Related Report
      2008 Final Research Report
  • [Presentation] 肺LCNEC細胞株の樹立と特性2008

    • Author(s)
      野村将春
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] ヒト肺癌細胞株2008

    • Inventor(s)
      野村将春
    • Industrial Property Rights Holder
      産業総合研究所
    • Industrial Property Number
      2008-257803
    • Filing Date
      2008-10-02
    • Related Report
      2008 Annual Research Report 2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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