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Valved patch with bulging sinus in the right ventricular outflow tract reconstruction

Research Project

Project/Area Number 19591640
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

MIYAZAKI Takako  Kyoto Prefectural University of Medicine, 医学研究科, 助教 (90405291)

Co-Investigator(Kenkyū-buntansha) YAMAGISHI Masaaki  京都府立医科大学, 医学研究科, 准教授 (40182422)
MAEDA Yoshinobu  京都府立医科大学, 医学部附属病院, 専攻医 (20438203)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords心臓血管外科学 / 右室流出路パッチ / 心臓大血管外科学
Research Abstract

先天性心疾患の外科治療において、肺動脈弁の代用弁を必要とする症例が多い。しかし、現状では、満足のいく代用弁は入手困難である。そこで、生体適合性が優れているExpanded polytetrafluoroethylene(EPTFE)が素材として最適であると考え、代用弁を手作りしてきた。しかし、長期的な弁機能には問題を有していた。そこで、生体の弁本来がもつ血管壁のふくらみ(bulging sinus)の中の渦上の血流が弁の動きに重要な役割を有することに着目し、EPTFEにbulging sinusを形成しその有用性を実証した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (14 results)

All 2008 2007 Other

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] 右室流出路再建術2008

    • Author(s)
      宮崎隆子、山岸正明
    • Journal Title

      Heart View 12

      Pages: 112-16

    • NAID

      40019921190

    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Journal Article] 右室流出路再建術2008

    • Author(s)
      宮崎隆子, 山岸正明
    • Journal Title

      Heart Vi ew 12

      Pages: 112-116

    • NAID

      40019921190

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Expanded polytetrafluoroethlene valved conduit and patch with bulging sinuses in right ventricular outflow tract re construction2007

    • Author(s)
      T Miyazaki, M Yamagishi, A Nakashima, K Fukae, T Nakano, H Yaku, H Kado
    • Journal Title

      The Journal of Thoracic and Cardiovascular Surgery 134

      Pages: 327-32

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] An expanded polytetrafluoroethlene-autologous aortic hybrid valve for right ventricular outflow tract reconstruction in the Ross procedure2007

    • Author(s)
      Miyazaki T, Yamagishi M, Shuntoh K, Yaku H
    • Journal Title

      Interactive Cardiovascular and Thoracic Surgery 6

      Pages: 163-66

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] 姑息的右室流出路再建における至適流出路径の検討2008

    • Author(s)
      宮崎隆子
    • Organizer
      第44回日本小児循環器学会
    • Place of Presentation
      福島
    • Related Report
      2008 Annual Research Report 2008 Final Research Report 2007 Annual Research Report
  • [Presentation] The Optimal Size of Expanded Polytetrafluoroethlene Valved Conduit in Right Ventricular Outflow Tract Reconstruction2008

    • Author(s)
      Miyazaki T
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeje, Korea
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] Midterm Pulmonary Autograft Function in the Ross Procedure2008

    • Author(s)
      Maeda Y
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeje, Korea
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] The Optimal Size of Expanded Polytetrafluoroethlene Val ved Conduit in Right Ventricular Outflow Tract Reconstr uction2008

    • Author(s)
      Miyazaki T
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pediatrie Cardiology and Card iac Surgery
    • Place of Presentation
      Jeje, Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] Midterm Pulmonary Autograft Function in the Ross Procedure2008

    • Author(s)
      Maeda Y.
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pedia tric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeje, Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] 右室流出路再建時の工夫-Bulging sinus付きePTFE Patchとfan-shaped ePTFE valveの検討2007

    • Author(s)
      前田吉宣
    • Organizer
      第53回近畿心臓外科研究会
    • Place of Presentation
      大阪
    • Year and Date
      2007-06-09
    • Related Report
      2008 Final Research Report
  • [Presentation] 右室流出路再建におけるePTFE valved graftの至適サイズの検討2007

    • Author(s)
      宮崎隆子
    • Organizer
      日本心臓血管外科学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2007-02-20
    • Related Report
      2008 Final Research Report
  • [Presentation] 右室流出路再建時の工夫-多施設共同研究によるBulging sinus付きePTFE patchとfan-shaped ePTFE valveの検討2007

    • Author(s)
      宮崎隆子
    • Organizer
      第60回日本胸部外科学会
    • Place of Presentation
      仙台
    • Related Report
      2008 Final Research Report
  • [Presentation] Fallot四徴症に対する右室流出路再建術-fan-shaped ePTFE valveの有用性2007

    • Author(s)
      宮崎隆子
    • Organizer
      第43回日本小児循環器学会
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] Expanded polytetrafluoroethylene valved patch with bulging sinuses and the fan-shaped valves in right ventricular outflow tract reconstruction in cases of tetralogy of Fallot

    • Author(s)
      Miyazaki T
    • Organizer
      The World Society for Pediatric and Congenital Heart Surgery
    • Place of Presentation
      Washington DC, U.S.A
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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