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Hybrid vessel and vascular patch using amniotic membrane

Research Project

Project/Area Number 19591641
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

YAMAGISHI Masaaki  Kyoto Prefectural University of Medicine, 医学研究科, 准教授 (40182422)

Co-Investigator(Kenkyū-buntansha) MIYAZAKI Takako  京都府立医科大学, 医学研究科, 助教 (90405291)
MAEDA Yoshinobu  京都府立医科大学, 附属病院, 専攻医 (20438203)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords右室流出路再建 / polytetrafluoroethylene / 羊膜 / ハイブリッド型人工血管
Research Abstract

肺動脈および右室流出路再建の代用素材として、材料強度の問題、耐用性の検討を行った。右室流出路はexpanded polytetrafluoroethylene(ePTFE)人工血管(ePTFE弁付)によるハイブリッド再建を行った。この検討では、肺血流は良好に保たれることが判明した。右室流出路に使用したePTFE弁は良好な機能を示した。羊膜ハイブリッド型人工血管の作成の基礎モデルとしての新鮮自己心膜は肺動脈、体静脈として生体適合性が良好で成長の可能性のある素材として有用性が示唆された。また羊膜と同等の薄さと強度を持つePTFE膜の肺動脈弁は右室流出路パッチに生体と同等のValsalva洞を作成することにより良好な弁機能を示すことが判明した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (15 results)

All 2009 2008

All Presentation (13 results) Book (2 results)

  • [Presentation] 乳児期右室流出路再建の治療戦略2009

    • Author(s)
      宮崎隆子、山岸正明、他
    • Organizer
      第39回日本心臓血管外科学会総会
    • Place of Presentation
      富山
    • Year and Date
      2009-04-24
    • Related Report
      2008 Final Research Report
  • [Presentation] 乳児期右室流出路再建の治療戦略2009

    • Author(s)
      宮崎隆子
    • Organizer
      第39回日本心臓血管外科学術総会
    • Place of Presentation
      富山
    • Year and Date
      2009-04-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] Right ventricular outflow tract selection : the superiority of the fan-shaped Gore-Tex membrane valve and Gore- Tex pa tch/conduit with bulging sinus2009

    • Author(s)
      山岸正明
    • Organizer
      The 17 th Annual Meeting of Asian Society for Cardiovascular and Thoracic Surgery
    • Place of Presentation
      Taipei
    • Year and Date
      2009-03-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] Right ventricular outflow tract selection: the superiority of the fan-shaped Gore-Tex membrane valve and Gore-Tex patch/conduit with bulging sinus2009

    • Author(s)
      山岸正明
    • Organizer
      The 17th Annual Meeting of Asian Society for Cardiovascular and Thoracic Surgery
    • Place of Presentation
      Taipei
    • Year and Date
      2009-03-06
    • Related Report
      2008 Final Research Report
  • [Presentation] 形態評価に基づいたMAPCA治療戦略2008

    • Author(s)
      宮崎隆子、山岸正明、他
    • Organizer
      第61回日本胸部外科学会定期学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-10-14
    • Related Report
      2008 Final Research Report
  • [Presentation] 形態評価に基づいたMAPCAの治療戦略2008

    • Author(s)
      宮崎隆子
    • Organizer
      第61回日本胸部外科学会定期学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-10-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] 姑息的右室流出路再建における至適流出路径の検討2008

    • Author(s)
      宮崎隆子、山岸正明、他
    • Organizer
      第44回日本小児循環器学会
    • Place of Presentation
      郡山
    • Year and Date
      2008-07-04
    • Related Report
      2008 Final Research Report
  • [Presentation] 姑息的右室流出路再建における指摘流出路径の検討2008

    • Author(s)
      宮崎隆子
    • Organizer
      第44回日本小児循環器学会総会
    • Place of Presentation
      郡山
    • Year and Date
      2008-07-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] The optimal size of polytetrafluoroethylene valved conduit in right ventricular outflow tract reconstruction2008

    • Author(s)
      宮崎隆子、山岸正明、他
    • Organizer
      The 2nd Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2008-05-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Fan-shaped Gore-Tex membrane valve and Gore-Tex patch/conduit with bulging sinus for RVOT reconstruction. Late results2008

    • Author(s)
      山岸正明、宮崎隆子、他
    • Organizer
      The 2nd Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2008-05-29
    • Related Report
      2008 Final Research Report
  • [Presentation] The optimal size of polytetrafluoroethylene valved conduit in right ventricular outflow tract reconstruetion2008

    • Author(s)
      宮崎隆子
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2008-05-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] Fan-shaped Gore-Tex membrane valve and Gore-Tex patch/conduit with bulging sinus for RVOT recons truetion : late results2008

    • Author(s)
      山岸正明
    • Organizer
      The 2^<nd> Asia-Pacific Congress of Pediatric Cardiology and Cardiac Surgery
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2008-05-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] 右室流出路再建におけるePTFE valved graftの至適サイズの検討2008

    • Author(s)
      宮崎 隆子
    • Organizer
      第38回日本心臓血管外科学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-02-20
    • Related Report
      2007 Annual Research Report
  • [Book] CIRCULATION VISUAL BEST 心臓血管外科テクニック2009

    • Author(s)
      山岸正明
    • Publisher
      メディカ出版
    • Related Report
      2008 Final Research Report
  • [Book] CIRCULATION VISUAL BEST 心臓血管外科テクニックIV先天性心疾患編2009

    • Author(s)
      山岸正明
    • Total Pages
      259
    • Publisher
      メディカ出版
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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