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The development of the computed analyzing system to predict the rupture risk of cerebral aneurysms

Research Project

Project/Area Number 19591670
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionNagoya University

Principal Investigator

SHIGERU Miyachi  Nagoya University, 大学院・医学系研究科, 准教授 (00293697)

Co-Investigator(Kenkyū-buntansha) 石井 克哉  名古屋大学, 情報連携基盤センター, 教授 (60134441)
Co-Investigator(Renkei-kenkyūsha) ISHII Katuya  名古屋大学, 情報連携基盤センター, 教授 (60134441)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords脳動脈瘤 / 破裂 / computational fluid dynamics / 血流動態解析 / 隆壁剪断力 / 二時流れ / 母血管軸 / 仮想モデル / 頭蓋内動脈瘤 / 破裂危険因子
Research Abstract

Computational fluid dynamicsをもちいて、未破裂脳動脈瘤の形態学的特徴より、破裂リスクを検討した。動脈瘤仮想モデルと実症例の臨床データを分析して、動脈瘤頚部と母血管軸の位置関係を検討した。
仮想動脈瘤と患者特異動脈瘤の両モデルともに、母血管軸に対する頚部の位置関係がわずかに変わるだけで、二次流れの発生など瘤内血流が変化することがわかり、これが破裂へのプロセスに関与することが示唆された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (39 results)

All 2008 2007

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (32 results)

  • [Journal Article] Risk of aneurysmal rupture : the importance of neck orifice positioning - assessment using computational flow simulation2008

    • Author(s)
      Ohshima T, Miyachi S, Hattori K, Takahashi I, Ishii K, Izumi T, Yoshida J
    • Journal Title

      Neurosurgery 62

      Pages: 767-775

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Morphological study of aneurysms at the junction of the superior cerebellar artery Interventional2008

    • Author(s)
      Iizuka H, Miyachi S, Ohshima T, Izumi T, Tsurumi A, Yoshida J
    • Journal Title

      Neuroradiology 14

      Pages: 259-266

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Risk of aneurysmal rupture : the importance of neck orifice positioning - assessment using computational flow simulation.2008

    • Author(s)
      Ohshima T, Miyachi S, Hattori K, Takahashi I, Ishii K, Izumi T, Yoshida J.
    • Journal Title

      Neurosurgery 62

      Pages: 767-775

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Morphological study of aneurysms at the junction of the superior cerebellar artery2008

    • Author(s)
      Iizuka H, Miyachi S, Ohshiraa T, Izumi T, Tsurumi A, Yoshida J
    • Journal Title

      Interventional Neuroradiology 14

      Pages: 259-266

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Risk of Aneurysmal Rupture: The Importance of Positioning of the Neck Orifice-Assessment Using Computational Flow Simulation2008

    • Author(s)
      Tomotaka Ohshima, Shigeru Miyachi, et. al.
    • Journal Title

      Neurosurgery 62(in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lomg term results of the embolization for unruptured cerebral aneurysms2007

    • Author(s)
      Miyachi S, Izumi T, Oshshima T, Tsurumi A, Hososhima O, Matsubara N, Kinkori T, Yoshida J
    • Journal Title

      Interventional Neuroradiology 13 Suppl 3. : 53

    • Related Report
      2008 Final Research Report
  • [Journal Article] ステントを用いた脳動脈瘤コイル塞栓術2007

    • Author(s)
      宮地 茂
    • Journal Title

      Medical torch 2(3)

      Pages: 26-27

    • Related Report
      2008 Final Research Report
  • [Presentation] 最新の脳血管内治療2008

    • Author(s)
      宮地 茂
    • Organizer
      第54回医科学応用財団講演会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 脳卒中の予防的治療 -最新の脳血管内治療-2008

    • Author(s)
      宮地 茂
    • Organizer
      桑名脳卒中勉強会
    • Place of Presentation
      桑名
    • Year and Date
      2008-11-20
    • Related Report
      2008 Final Research Report
  • [Presentation] 脳卒中の予防的治療-最新の脳血管内治療-2008

    • Author(s)
      宮地茂
    • Organizer
      桑名脳卒中勉強会
    • Place of Presentation
      桑名
    • Year and Date
      2008-11-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 脳卒中の予防外科-血管内治療-2008

    • Author(s)
      宮地 茂
    • Organizer
      第2回東名セミナー
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-04
    • Related Report
      2008 Final Research Report
  • [Presentation] 脳卒中の予防外科 -血管内治療-2008

    • Author(s)
      宮地茂
    • Organizer
      第2回東名セミナー
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] Time resolved three‐dimensional phase-contrast MRIを用いた脳動脈瘤の血流動態解析2008

    • Author(s)
      内藤丈裕, 宮地茂, 泉孝嗣, 鶴見有史, 細島理, 松原功明, 若林俊彦
    • Organizer
      第67回日本脳神経外科学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2008-10-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] 内頚動脈瘤塞栓術後の再発と再治療2008

    • Author(s)
      宮地茂
    • Organizer
      第4回デバイス&テクニックセミナー
    • Place of Presentation
      大沼
    • Year and Date
      2008-07-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 困難な脳動脈瘤に対する塞栓術のTips & Pitfall2008

    • Author(s)
      宮地茂
    • Organizer
      第37回日本脳卒中の外科学会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-20
    • Related Report
      2008 Final Research Report
  • [Presentation] 脳動脈瘤塞栓術のコツとピットフォール2008

    • Author(s)
      宮地茂
    • Organizer
      備後脳神経外科医会学術講演会
    • Place of Presentation
      福山
    • Year and Date
      2008-03-14
    • Related Report
      2008 Final Research Report
  • [Presentation] 血流動態モデルによるコイル留置目標ラインの検討-VA-PICA分岐部動脈瘤編2008

    • Author(s)
      大島共貴、宮地 茂
    • Organizer
      第24回日本脳神経血管内治療学会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Time -resolved three-dimensional phase-contrast MRIを用いた脳動脈瘤の血流動態解析2008

    • Author(s)
      内藤丈裕、宮地 茂、泉 孝嗣、鶴見有史、細島 理、松原功明、若林俊彦
    • Organizer
      第24回日本脳神経血管内治療学会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 脳神経外科における医療事故とリスク管理2008

    • Author(s)
      宮地 茂、相馬孝博、高橋英夫、宮田はるみ、後藤百万、若林俊彦
    • Organizer
      第67回日本脳神経外科学会総会
    • Place of Presentation
      盛岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Time resolved three-dimensional phase-contrast MRIを用いた脳動脈瘤の血流動態解析2008

    • Author(s)
      内藤丈裕、宮地 茂、泉 孝嗣、鶴見有史、細島 理、松原功明、若林俊彦
    • Organizer
      第67回日本脳神経外科学会総会
    • Place of Presentation
      盛岡
    • Related Report
      2008 Final Research Report
  • [Presentation] 内頚動脈瘤塞栓術後の再発と再治療2008

    • Author(s)
      宮地 茂
    • Organizer
      第4回デバイス& テクニックセミナー
    • Place of Presentation
      大沼
    • Related Report
      2008 Final Research Report
  • [Presentation] Contribution of the embolization for unruptured aneurysms on the technical point of view and the risk management2008

    • Author(s)
      Miyachi S
    • Organizer
      9th meeting of Asian-Australasian federation of interventional & therapeutic neuroradiology (AAFITN)
    • Place of Presentation
      Taipei
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 未破裂脳動脈瘤塞栓術における術中トラブルに対する予防法とトラブルシューティング(シンポジウム)2008

    • Author(s)
      宮地茂、泉孝嗣、大島共貴、鶴見有史、細島理、錦古里武志、松原功明、吉田純
    • Organizer
      第37回日本脳卒中の外科学会
    • Place of Presentation
      京都
    • Related Report
      2008 Final Research Report
  • [Presentation] 長期成績から見た未破裂脳動脈瘤に対する塞栓術の功罪2008

    • Author(s)
      泉孝嗣, 宮地茂, 大島共貴, 〓見有史, 細島理, 松原功明, 錦古里武志
    • Organizer
      第33回日本脳卒中学会総会
    • Place of Presentation
      京都
    • Related Report
      2008 Final Research Report
  • [Presentation] 内頸動脈瘤に対する眼動脈起始部を含む血管内トラッピング術の有用性と安全性2008

    • Author(s)
      細島 理、宮地 茂, 泉孝嗣, 〓見有史, 松原功明, 内藤丈裕, 若林俊彦
    • Organizer
      第37回日本脳卒中の外科学会
    • Place of Presentation
      京都
    • Related Report
      2008 Final Research Report
  • [Presentation] Contribution of the embolization for unruptured aneurysms on the technical point of view and the risk management2007

    • Author(s)
      宮地 茂
    • Organizer
      World Federation of Neurosurgical Societies, 13th Interim Meeting/The 12th Asian-Australasian Congress of neurological Surgeons
    • Place of Presentation
      名古屋
    • Year and Date
      2007-11-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 未破裂脳動脈瘤に対する塞栓術の長期成績-有効性とピットフォール-2007

    • Author(s)
      宮地 茂
    • Organizer
      第66回日本脳神経外科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] LONG TERM RESULTS OF THE EMBOLIZATION FOR UNRUPTURED CEREBRAL ANEURYSMS2007

    • Author(s)
      宮地 茂
    • Organizer
      The 9th Congress of World Federation of Interventional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing
    • Year and Date
      2007-09-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] The risk of aneurysmal rupture: the importance of neck position-assessment using the computational flow simulation2007

    • Author(s)
      大島 共貴
    • Organizer
      The 9th Congress of World Federation of Interventional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing
    • Year and Date
      2007-09-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Additional coil embolization following for the recurrent saccular intracranial aneurysms2007

    • Author(s)
      大島 共貴
    • Organizer
      The 9th Congress of World Federation of Interventional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing
    • Year and Date
      2007-09-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] Intentional occlusion of the ophthalmic artery in the embolization of carotid aneurysms2007

    • Author(s)
      細島 理
    • Organizer
      The 9th Congress of World Federation of Interventional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing
    • Year and Date
      2007-09-09
    • Related Report
      2007 Annual Research Report
  • [Presentation] 治療困難な脳動脈瘤に対する血管内治療2007

    • Author(s)
      宮地 茂
    • Organizer
      第8回近畿脳神経血管内治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-09-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 血流動態解析モデルによる動脈瘤破裂危険因子の検討 : Terminal type動脈ルウにおける動脈瘤頚部と母血管軸の位置関係について2007

    • Author(s)
      大島共貴、宮地茂、吉田純
    • Organizer
      第23回日本脳神経血管内治療学会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] 血流動態解析モデルによる動脈瘤破裂危険因子の検討 : Terminal type動脈瘤における動脈瘤頚部と母血管軸の位置関係について2007

    • Author(s)
      大島共貴、宮地茂、吉田純
    • Organizer
      第67回日本脳神経外科学会総会
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] 未破裂脳動脈瘤に対する塞栓術の長期成績 -有効性とピットフォール-2007

    • Author(s)
      宮地 茂、泉 孝嗣、大島共貴、鶴見有史、細島 理、松原功明、錦古里武志、吉田 純
    • Organizer
      第67回日本脳神経外科学会総会
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] Lomg term results of the embolization for unruptured cerebral aneurysms2007

    • Author(s)
      Miyachi S, Izumi T, Oshshima T, Tsurumi A, Hososhima O, Matsubara N, Kinkori T, Yoshida J
    • Organizer
      The 9^<th> Congress of the World Federation of Intervenitional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing, China
    • Related Report
      2008 Final Research Report
  • [Presentation] Additional coil embolization following for the recurrent saccular intracranial aneurysms2007

    • Author(s)
      Ohshima T, Miyachi S, Yoshida J
    • Organizer
      The 9^<th> Congress of the World Federation of Intervenitional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing, China
    • Related Report
      2008 Final Research Report
  • [Presentation] The risk of aneurysmal rupture : the importance of neck position? - assessment using computational flow simulation2007

    • Author(s)
      Ohshima T, Miyachi S, Hattori K, Takahashi I, Ishii K, Yoshida J
    • Organizer
      The 9^<th> Congress of the World Federation of Intervenitional and Therapeutic Neuroradiology
    • Place of Presentation
      Beijing, China
    • Related Report
      2008 Final Research Report
  • [Presentation] Computational analysis of flow dynamics in the intracranial aneurysms for assessing risk of rupture by computational models2007

    • Author(s)
      Ohshima T, Miyachi S, Hattori K, Takahashi I, Ishii K, Yoshida J
    • Organizer
      The 4^<th> International Intracranial Stent Meeting
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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