Synaptic mechanism in emotional nervous system under establishment of chronic pain
| Project/Area Number |
19591736
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
IKEDA Ryo Jikei University School of Medicine, 医学部, 助教 (20439772)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Fusao 東京慈恵会医科大学, 医学部, 教授 (20169519)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 筋 / 神経病学 / 扁桃体 / 慢性痛 / シナプス伝達 / 神経因性疼痛 |
|---|
| Research Abstract |
New modalities of synaptic plasticity distinct from acute pain occurred in the amygdala under establishment of neuropathic pain. Moreover, this potentiation was dependent on the structural changes of synapse in the amygdala. It was thought that this result became important for establishing a new treatment method to relief chronic pain.
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Report
(4 results)
Research Products
(28 results)
