Development of functional imaging in joint abnormalities for sensitive assessment of drug efficacy
Project/Area Number |
19591757
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Orthopaedic surgery
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Research Institution | Osaka University |
Principal Investigator |
NISHII Takashi Osaka University, 医学系研究科, 寄附講座准教授 (70304061)
|
Co-Investigator(Kenkyū-buntansha) |
KURODA Kagayaki 東海大学, 情報理工学部, 准教授 (70205243)
SUGANO Nobuhiko 大阪大学, 医学系研究科, 教授 (70273620)
TANAKA Hisashi 大阪大学, 医学系研究科, 講師 (40294087)
SATO Yoshinobu 大阪大学, 医学系研究科, 准教授 (70243219)
SAKAI Takashi 大阪大学, 医学部附属病院, 助教 (00444539)
MATSUOKA Yuichirou 先端医療振興財団, 分子イメージング研究グループ, 研究員 (80372150)
|
Project Period (FY) |
2007 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 関節病学 / 変形性関節症 / MRI / T2 mapping / 関節軟骨 / 機能的イメージング |
Research Abstract |
To allow sensitive evaluation of early cartilage abnormalities in the hip or knee joints, we developed quantitative MR imaging system under in-situ loading system. By experimental and clinical studies, cartilage T2 mapping by loading was indicated as a promising index for evaluating early cartilage abnormalities and abnormal biomechanical conditions around the articular cartilage.
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Report
(4 results)
Research Products
(34 results)
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[Presentation] 荷重下の関節軟骨MRI評価2009
Author(s)
西井孝, 塩見俊行, 坂井孝司, 高尾正樹, 田中壽, 吉川秀樹, 菅野伸彦
Organizer
第14回日本関節症研究会学術集会
Place of Presentation
横浜
Year and Date
2009-05-23
Related Report
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