ABO-compatible red blood cell transfusion practices in the operating room and the following hemolytic reactions.
Project/Area Number |
19591803
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Anesthesiology/Resuscitation studies
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Research Institution | Kyushu University |
Principal Investigator |
IRITA Kazuo Kyushu University, 病院, 准教授 (80168541)
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Co-Investigator(Kenkyū-buntansha) |
森田 潔 岡山大学, 医歯薬学総合研究科, 教授 (40108171)
津崎 晃一 慶應義塾大学, 医学部, 助教授 (90138107)
半田 誠 慶應義塾大学, 医学部, 助教授 (40129614)
稲田 英一 順天堂大学, 医学部, 教授 (40193552)
|
Co-Investigator(Renkei-kenkyūsha) |
INADA Eiichi 順天堂大学, 医学部, 教授 (40193552)
TSUZAKI Koichi 慶応義塾大学, 医学部, 助教授 (90138107)
MORITA Kiyoshi 岡山大学, 医歯薬学総合研究科, 教授 (40108171)
|
Project Period (FY) |
2007 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 手術 / 大量出血 / 緊急輸血 / 異型適合血輸血 / 未交差同型血輸血 / 溶血反応 / 溶血性副作用 / 不規則抗体 / 放射線照射 / 輸血後移植片対宿主病 / 高カリウム血症 / 輸血 / 異型適合血 |
Research Abstract |
We performed a questionnaire survey regarding the present status of critical hemorrhage/blood transfusion occurring in the operating room on an institutional scale and individual blood transfusion management in cases of massive hemorrhage (≧5,000ml) in hospitals with ≧500 beds and those with an accredited Department of Anesthesiology regarded as regional hospitals. Thirty-seven hundred forty-eight patients with massive hemorrhage were registered between 2006 and 2008. Although the mortality rate of these patients was 19%, ABO-compatible red blood cell transfusion was performed only 1.4% of these patients. Publication of the "Guidelines for the Management of Critical Hemorrhage" in 2007 has not promoted ABO-compatible red blood cell transfusion yet. Although ABO-compatible red blood cell was transfused in eighty-three patients regardless of the amount of blood loss, this transfusion management was not associated with hemolytic reactions. Because the major reason to avoid ABO-compatible red blood cell transfusion was fear of hemolytic reactions, enlightening the safety of ABO-compatible red blood cell transfusion seemed to be mandatory.
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Report
(6 results)
Research Products
(65 results)
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[Journal Article] 麻酔科認定病院の手術室で発生している大量出血とその対応に関する実態調査2009
Author(s)
入田和男, 稲田英一, 吉村速, 蕨謙吾, 津崎晃一, 稲葉頌一, 半田誠,上村知恵, 紀野修一, 益子邦洋, 矢野哲, 亀井良政, 久保隆彦
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Journal Title
NAID
Related Report
Peer Reviewed
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[Journal Article] 麻酔科認定病院の手術室で発生している大量出血とその対応に関する実態調査2009
Author(s)
入田和男, 稲田英一, 吉村速, 蕨謙吾, 津崎晃一, 稲葉頌一, 半田誠, 上村知恵, 紀野修一, 益子邦洋, 矢野哲, 亀井良政, 久保隆彦
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Journal Title
NAID
Related Report
Peer Reviewed
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[Presentation] 危機的出血2010
Author(s)
入田和男
Organizer
日本麻酔科学会第9回リフレッシャーコース
Place of Presentation
福岡市
Year and Date
2010-06-05
Related Report
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[Presentation] 危機的出血2010
Author(s)
入田和男
Organizer
日本麻酔科学会第9回リフレッシャーコース
Place of Presentation
福岡国際会議場(福岡市)
Year and Date
2010-06-05
Related Report
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