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Comprehensive analysis of abnormal bladder sensation andurothelial dysfunction in overactive bladder

Research Project

Project/Area Number 19591831
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionAsahikawa Medical College

Principal Investigator

KAKIZAKI Hidehiro  Asahikawa Medical College, 医学部, 教授 (10241324)

Co-Investigator(Kenkyū-buntansha) 倉 達彦  旭川医科大学, 医学部, 助教 (00431411)
沼田 篤  旭川医科大学, 医学部, 助教 (00250564)
Co-Investigator(Renkei-kenkyūsha) NUMATA Atsushi  旭川医科大学, 医学部, 助教 (00250564)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords過活動膀胱 / 膀胱知覚 / 尿路上皮
Research Abstract

本研究では、尿意切迫感や頻尿などの蓄尿症状を呈する特発性過活動膀胱や前立腺肥大症に付随する過活動膀胱、間質性膀胱炎を対象に検討を行った。過活動膀胱における膀胱知覚の異常は、知覚神経であるA δ線維とC線維の刺激閾値とは相関せず、膀胱の粘膜下や尿路上皮に存在するさまざまな知覚受容体の発現量と相関することが示唆された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (9 results)

All 2009 2008 2007

All Journal Article (5 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Book (2 results)

  • [Journal Article] 下部尿路機能障害に対する薬物療法の最前線2008

    • Author(s)
      柿崎秀宏
    • Journal Title

      泌尿器科外科 21

      Pages: 247-249

    • Related Report
      2008 Final Research Report
  • [Journal Article] 下部尿路機能障害に対する薬物療法の最前線2008

    • Author(s)
      柿崎秀宏
    • Journal Title

      泌尿器外科 21

      Pages: 247-249

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Defining overactive bladder as hypersensitivity2007

    • Author(s)
      Yamaguchi O, Honda K, Nomiya M, Shishido K, Kakizaki H, Tanaka H, et.al.
    • Journal Title

      Neurourology and Urodynamics 26

      Pages: 904-907

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 過活動膀胱のすべて : 下部尿路機能の基礎2007

    • Author(s)
      柿崎秀宏、沼田 篤、倉 達彦、加藤祐司、川上憲裕
    • Journal Title

      臨床泌尿器科 61

      Pages: 571-577

    • Related Report
      2008 Final Research Report
  • [Journal Article] BPHの手術適応決定-Pressure-flow studyに勝るものはあるか-2007

    • Author(s)
      柿崎秀宏、北 雅史、和田直樹、玉木 岳、倉 達彦、沼田 篤
    • Journal Title

      Urology View 5

      Pages: 72-77

    • Related Report
      2008 Final Research Report
  • [Presentation] Is pressure-flow study useful to predict the outcome of transurethral resection of prostate2008

    • Author(s)
      Wada N, Nakazono S, Tamaki G, Numata A, Kakizaki H
    • Organizer
      38th Annual Meeting of the International Continence Society
    • Place of Presentation
      Cairo, Egypt
    • Year and Date
      2008-10-22
    • Related Report
      2008 Final Research Report
  • [Presentation] Is pressre-flow study useful to predict the outcome of Transurethral resection of purostate?2008

    • Author(s)
      Wada, Nakazono, Tamaki, Numata, Kakizaki
    • Organizer
      38^<th> Annual Meeting of the International Continence Society
    • Place of Presentation
      Cairo, Egypt
    • Year and Date
      2008-10-22
    • Related Report
      2008 Annual Research Report
  • [Book] よくわかって役に立つ前立腺肥大症のすべて : 排尿障害と排尿神経機構2009

    • Author(s)
      和田直樹、柿崎秀宏
    • Publisher
      永井書店
    • Related Report
      2008 Final Research Report
  • [Book] よくわかって役に立つ排尿障害のすべて : 過活動膀胱2007

    • Author(s)
      柿崎秀宏、沼田 篤、倉 達彦
    • Publisher
      永井書店
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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