Molecular mechanism of hormone-refractory progression of prostate cancer
| Project/Area Number |
19591834
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Chiba University |
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Principal Investigator |
SUZUKI Hiroyoshi Chiba University, 大学院・医学研究院, 准教授 (60301818)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 前立腺癌 / ホルモン療法 / 分子生物学 / バイオマーカー / プロテオミクス / 神経内分泌分化 / IGF-I / 再燃 / 遺伝子 / アンドロゲン |
|---|
| Research Abstract |
We have investigated molecular mechanisms related to hormonary-relapse of prostate cancers. Especially, hormonal environment and neuroendocrine differentiation of prostate cancers have been studied. Also, we have identified Apo C-1 to be elevated in the sera of hormone-refractory prostate cancer patients.
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Report
(4 results)
Research Products
(112 results)
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[Journal Article] Prospective evaluation of selection criteria for active surveillance in Japanese patients with stage T1cN0M0 prostate cancer2008
Author(s)
Kakehi Y, Kamoto T, Shiraishi T, Ogawa O, Suzukamo Y, Fukuhara S, Saito Y, Tobisu KI, Kakizoe T, Shibata T, Fukuda H, Akakura K, Suzuki H, et al.
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Journal Title
Jpn J Clin Oncol 38
Pages: 122-128
Related Report
Peer Reviewed
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