| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
The cine-mode MRI suggested that the area of the low signal in the muscle layer right under the endometrium was broad and sustained in the patients with severe dysmenorrhea. Ischemia and pain was caused in the uterine muscle with strong shrinkage. Moreover, the value of serum osteopontin was useful biomarker to judge the severity of symptoms and to detect ovarian cancer related with endometriosis. The prospective, double-blind, randomized, placebo-controlled study resulted that leukotorien recepter antagonist was an effective alternative for treatment of endometriosis. It resulted that further studies using the cine-mode MRI and the value of serum osteopontin are enable to evaluate the severity of dysmenorrhea and the effectiveness of the treatment for endometriosis.
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