To establish the prediction and to elucidate the pathophysiology of placenta previa accereta
| Project/Area Number |
19591909
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Saitama Medical University |
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Principal Investigator |
ITAKURA Atsuo Saitama Medical University, 医学部, 教授 (70262897)
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| Co-Investigator(Kenkyū-buntansha) |
KAJIHARA Takeshi 埼玉医科大学, 医学部, 准教授 (80286103)
SUMIGAMA Seiji 名古屋大学, 医学研究科, 助教 (50378121)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 産科学 / 前置癒着胎盤 / アポトーシス / 内腸骨動脈結紮術 / 子宮動脈塞栓術 / 癒着胎盤 |
|---|
| Research Abstract |
前置癒着胎盤の疫学調査を行い、日本国内における発生率とその危険因子を明らかとした。また手術時の大量出血を予防するためのInterventional Radiology を用いた集学的治療の効果と限界について検討を行い、これも報告した。前置癒着胎盤では、脱落膜が欠損する部位に胎盤絨毛が浸潤し、子宮平滑筋をapoptosis に陥らせ、胎盤が置換することを基礎研究によって明らかとした。
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Report
(3 results)
Research Products
(30 results)
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[Journal Article] The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium.2008
Author(s)
Cloke B, Huhtinen K, Fusi L, Kajihara T, Yliheikkila M, Ho KK, Teklenburg G, Lavery S, Jones MC, Trew G, Kim JJ, Lam EW, Cartwright JE, Poutanen M, Brosens JJ
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Journal Title
Endocrinology 149
Pages: 4462-4474
Related Report
Peer Reviewed
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[Journal Article] Angiotensin II mimics the hypoxic effect on regulating trophoblast proliferation and differentiation in human placental explant cultures.2008
Author(s)
Araki-Taguchi M, Nomura S, Ino K, Sumigama S, Yamamoto E, Kotani-Ito T, Hayakawa H, Kajiyama H, Shibata K, Itakura A, Kikkawa F.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Placenta previa increta/percreta in Japan-a retrospective study of ultrasound findings, management and clinical course.2007
Author(s)
Sumigama S, Itakura A, Ota T, Okada M, Kotani T, Hayakawa H, Yoshida K, Ishikawa K, Hayashi K, Kurauchi O, Yamada S, Nakamura H, Matsusawa K, Sakakibara K, Ito M, Kawai M, Kikkawa F
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Journal Title
J Obstet Gynecol Res. 33
Pages: 606-611
NAID
Related Report
Peer Reviewed
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[Presentation] 前回帝切前置胎盤症例における超音波術前診断の検討2008
Author(s)
岩田睦、村山敬彦, 上山明美, 市川美和, 小野義久, 松永茂剛, 松村英祥, 斉藤正博, 高木健次郎, 板倉敦夫, 馬場一憲, 関博之
Organizer
第60 回日本産科婦人科学会
Place of Presentation
横浜
Year and Date
2008-04-13
Related Report
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