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A new approach to assess the central auditory system in Congenital deaf patients with cochlear implants.

Research Project

Project/Area Number 19591967
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionOsaka University

Principal Investigator

OOSAKI Yasuhiro  Osaka University, 医学系研究科, 助教 (30437321)

Co-Investigator(Kenkyū-buntansha) DOI Katsumi  大阪大学, 大学院・医学系研究科, 准教授 (40243224)
KUBO Takeshi  大阪大学, 大学院・医学系研究科, 教授 (30107031)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords人工内耳 / NIRS(近赤外分光法) / 難聴 / 小児 / 大脳聴覚野 / 発達
Research Abstract

言語修得期前に両側聾となった小児に対し人工内耳埋め込み術が行われており、当院においても多数の手術が施行されている。人工内耳は手術手技だけではなく、電気刺激強度の調節(フィッティング)を含めた術後のフォローアップが非常に重要となっており、当科でも熟練した言語聴覚師らが診療に当たっている。一方、近年人工内耳手術が低年齢化する傾向にあり、人工内耳による音刺激時に実際に音が聞こえているかの評価が難しい症例が増え、客観的な聴覚検査方法の確立が求められている。今回我々は、人工内耳を通じて音を聴いた際の大脳聴覚野の脳活動をNIRS(近赤外分光法)を用いて検査することで、小児における客観的な聴覚検査法を確立することを目的とした。言語音による刺激を提示した際、無音状態と比較して側頭葉を中心に脳血流の変化が見られ、人工内耳刺激によって聴覚野が活動することを反映していると考えられた。結果をアジア太平洋国際人工内耳学会にて発表、英文のproceedingが掲載された。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (8 results)

All 2009 2008 2007

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (1 results)

  • [Journal Article] Activation of the Auditory Cortex in a Child with a Cochlear Implant : an Optical Topography Study2009

    • Author(s)
      Osaki Y, Doi K, Masumura C, Suwa K, Hanamoto M, Inohara H.
    • Journal Title

      Conf Proc Asia Pacific Symposium on Cochlear Implants and Related Sciences (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relative contribution of walking velocity and stepping frequency to the neural control of locomotion2008

    • Author(s)
      Osaki Y, Kunin M, Cohen B, Raphan T.
    • Journal Title

      Exp Brain Res 185(1)

      Pages: 121-135

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain responses during the first desire to void : A positron emission tomography study2008

    • Author(s)
      Takao T, Tsujimura A, Miyagawa Y, Kiuchi H, Ueda T, Hirai T, Komori K, Takada S, Nonomura N, Osaki Y, Enomoto K, Hatazawa J, Okuyama A.
    • Journal Title

      Int J Urol 15(8)

      Pages: 724-728

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The role of CT and (18)F-FDG PET in managing the neck in node-positive head and neck cancer after chemoradiotherapy2008

    • Author(s)
      Inohara H, Enomoto K, Tomiyama Y, Yoshii T, Osaki Y, Higuchi I, Inoue T, Hatazawa J.
    • Journal Title

      Acta Otolaryngol (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional kinematics and dynamics of the foot during walking : a model of central control mechanisms2007

    • Author(s)
      Osaki Y, Kunin M, Cohen B, Raphan T
    • Journal Title

      Exp Brain Res 176(3)

      Pages: 476-496

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Motor cortex stimulation in patients with deafferentation pain : activation of the posterior insula and thalamus2007

    • Author(s)
      Kishima H, Saitoh Y, Osaki Y, Nishimura H, Kato A, Hatazawa J, Yoshimine T.
    • Journal Title

      J Neurosurg 107(1)

      Pages: 43-48

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential brain processing of audiovisual sexual stimuli in men : comparative positron emission tomography study of the initiation and maintenance of penile erection during sexual arousal2007

    • Author(s)
      Miyagawa Y, Tsujimura A, Fujita K, Matsuoka Y, Takahashi T, Takao T, Takada S, Matsumiya K, Osaki Y, Takasawa M, Oku N, Hatazawa J, Kaneko S, Okuyama A.
    • Journal Title

      Neuroimage 36(3)

      Pages: 830-842

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] Activation of the Auditory Cortex in Children with Cochlear Implants an Optical Topography Study2009

    • Author(s)
      Osaki Y, Doi K, Masumura C, Suwa K, Hanamoto M, Inohara H.
    • Organizer
      In : 7th Asia Pacific Symposium on Cochlear Implants and Related Sciences
    • Place of Presentation
      Singapore
    • Related Report
      2008 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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