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The mechanisms of VEGF-induced Neovascular Sprouts in ex vivo Retinal Angiogenesis Model

Research Project

Project/Area Number 19592016
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionKyoto University

Principal Investigator

NISHIJIMA Kazuaki  Kyoto University, 医学研究科, 助教 (50432381)

Co-Investigator(Kenkyū-buntansha) TUJIKAWA Akitaka  京都大学, 医学研究科, 助教 (40402846)
尾島 知成  京都大学, 医学研究科, 助教 (00402834)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords血管新生 / 網膜培養 / 血管内皮増殖因子 / SDF-1 / CXCR4 / マイクログリア / stromal cell-derived factor-1 / 網膜 / VEGF
Research Abstract

SDF-1/CXCR4はtip cellやマイクログリアに作用し、網膜の血管新生に寄与していることが明らかになった。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (2 results)

All 2008

All Presentation (2 results)

  • [Presentation] Stromal Derived Factor-1 (SDF-1)/CXCR4 Axis Contributes to the Neovascular Sprouting in Retinal Angiogenesis2008

    • Organizer
      The Association for Research in Vision and Ophthalmology Meeting
    • Place of Presentation
      Fort Lauderdale
    • Year and Date
      2008-04-27
    • Related Report
      2008 Final Research Report
  • [Presentation] Stroraal Derived Factor-1 (SDF-1)/CXCR4 Axis Contributes to the Neovascular Sprouting in Retinal Angiogenesis2008

    • Author(s)
      N. Unoki, T. Murakami, K. Nishijima, N. Yoshimura
    • Organizer
      The Association for Research in Vision and Ophthalmology Meeting
    • Place of Presentation
      Fort Lauderdale
    • Year and Date
      2008-04-27
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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