The mechanisms of VEGF-induced Neovascular Sprouts in ex vivo Retinal Angiogenesis Model
| Project/Area Number |
19592016
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Ophthalmology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
NISHIJIMA Kazuaki Kyoto University, 医学研究科, 助教 (50432381)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TUJIKAWA Akitaka 京都大学, 医学研究科, 助教 (40402846)
尾島 知成 京都大学, 医学研究科, 助教 (00402834)
|
|---|
| Project Period (FY) |
2007 – 2008
|
| Project Status |
Completed (Fiscal Year 2008)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 血管新生 / 網膜培養 / 血管内皮増殖因子 / SDF-1 / CXCR4 / マイクログリア / stromal cell-derived factor-1 / 網膜 / VEGF |
|---|
| Research Abstract |
SDF-1/CXCR4はtip cellやマイクログリアに作用し、網膜の血管新生に寄与していることが明らかになった。
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Report
(3 results)
Research Products
(2 results)
