| Project/Area Number |
19592074
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Kyoto University |
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Principal Investigator |
KATAOKA Kazuya Kyoto University, 医学研究科, 非常勤講師 (10314189)
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| Co-Investigator(Kenkyū-buntansha) |
NOSE Kensuke 京都大学, 医学研究科, 非常勤講師 (80379057)
鈴木 義久 田附興風会, 第3研究部, 研究主幹 (30243025)
井出 千束 藍野大学, 医療保健学部, 教授 (70010080)
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| Project Period (FY) |
2007 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 慢性期脊髄損傷 / 細胞外マトリクス / アルギン酸ゲル / bFGF / 徐放 / ヘパリン様ペプチド / 脊髄空洞 / 中枢神経 / 脊髄再生 / 浸透圧ポンプ / 慢性脊髄損傷 / 脊髄内空洞 |
|---|
| Research Abstract |
We made the device for making injury to spinal cords of rats. Using this device we could make fixed damage to spinal cords. After 2 weeks, we observe fixed size cavities in the spinal cords using immunohistochemical staining. We injected the alginate gel and the bFGF applied alginate gel. After injection, we investigate the spinal cord. We confirmed inhibition of enlargement of the cavities and partial regeneration of nerve fibers, but we could not find statistically significance.
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