Establishment of antibody titer measurement against Vibrio vulnificus
| Project/Area Number |
19592091
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Emergency medicine
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| Research Institution | Saga University |
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Principal Investigator |
ARAKI Kazukuni Saga University, 医学部, 准教授 (50193066)
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| Co-Investigator(Kenkyū-buntansha) |
MITHUMIZO Shinji 佐賀大学, 医学部, 講師
NAKASHIMA Mikio 佐賀大学, 医学部, 教授 (70315191)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 集中治療医学 / Vibrio vulnificus / Micro-IF / 血清抗体価 / 血清抗体価測定法 / 壊死性筋膜炎 / Micro-IF assay / micro-IF assay |
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| Research Abstract |
We studied blood plasma IgG antibody (IgG Ab) titer in Vibrio vulnificus patients and two control groups(chronic liver dysfunction group and normal liver function group). To determine the Vibrio vulnificus antigens, we investigated two-dimensional gel electrophoresis and western blot. We discovered the time course of IgG Ab titer and specific antigen. Although we could not conclude that the IgG Ab titer analysis system is useful for screening for people who are susceptible to Vibrio vulnificus infection, it seems possible to predict the prognosis of the patients.
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Report
(4 results)
Research Products
(20 results)
