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MR lymphography in the head and neck

Research Project

Project/Area Number 19592174
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionNagasaki University

Principal Investigator

角 美佐  Nagasaki University, 大学院・医歯薬学総合研究科, 准教授 (90284702)

Co-Investigator(Kenkyū-buntansha) 中村 卓  長崎大学, 大学院・医歯薬学総合研究科, 教授 (30172406)
田代 茂樹  長崎大学, 大学院・医歯薬学総合研究科, 助教 (20300882)
角 忠輝  長崎大学, 大学院・医歯薬学総合研究科, 助教 (80284701)
木村 泰男  長崎大学, 大学院・医歯薬学総合研究科, 助教 (30253686)
高木 幸則  長崎大学, 大学院・医歯薬学総合研究科, 助教 (30295084)
佐々木 美穂  長崎大学, 医学部・歯学部附属病院, 助教 (10437874)
榮田 智  長崎大学, 大学院医歯薬学総合研究科, 助教 (80325662)
市川 陽子  長崎大学, 医学部・歯学部附属病院, 助教 (90380857)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2007: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords頭頸部癌 / 転移リンパ節 / MRI / 頸部リンパ節転移 / 被膜外浸潤 / 扁平上皮癌 / 原発巣 / みかけ拡散係数 / 造影ダイナミックスタディ / time-signal intensity curve / Balanced TFE / MR lymohography
Research Abstract

頭頸部悪性腫瘍の大部分を占める扁平上皮癌において、リンパ節転移存在の予後への影響は大きく、また、転移リンパ節が被膜外浸潤を伴えば、さらに予後が悪くなると報告されている。そこで、MRIを用いた被膜外浸潤の検出能について検討を行ったところ、脂肪抑制T2強調像が診断に有用であることがわかった。転移リンパ節周囲にみられる脂肪抑制T2強調像における高信号域は病理組織学的にはリンパ浮腫を反映すると考えられる。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (40 results)

All 2009 2008 2007

All Journal Article (19 results) (of which Peer Reviewed: 3 results) Presentation (18 results) Book (3 results)

  • [Journal Article] Diagnostic importance of focal defects in the apparent diffusion coefficient-based differentiation between lymphoma and squamous cell carcinoma nodes in the neck2009

    • Author(s)
      Sumi M, Nakamura T
    • Journal Title

      Eur Radiol 19 19

      Pages: 975-981

    • Related Report
      2008 Final Research Report
  • [Journal Article] Diffusion-weighted MR imaging of ameloblastomas and keratocystic odontogentic tumors : differentiation by apparent diffusion coefficient of cystic lesions2009

    • Author(s)
      Sumi M, Ichikawa Y, Katayama I, Tashiro S, Nakamura T
    • Journal Title

      AJNR Am J Neuroradiol 29 29

      Pages: 1897-1901

    • Related Report
      2008 Final Research Report
  • [Journal Article] Diagnostic importance of focal defects in the apparent diffusion coefficient-based differentiation between lymphoma and squamous cell carcinoma nodes in the neck2009

    • Author(s)
      Sumi M, Nakamura T
    • Journal Title

      European Radiology (掲載確定In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surgical anatomy of the sphenoid sinus on the CT using multiplanar reconstruction technique2008

    • Author(s)
      Enatsu K, Takasaki K, Kase K, Jinnouchi S, Kumagami H, Nakamura T, Takahashi H
    • Journal Title

      Otolaryngol Head Neck Surg 138

      Pages: 182-186

    • Related Report
      2008 Final Research Report
  • [Journal Article] MR imaging criteria for the prediction of extranodal spread of metastatic2008

    • Author(s)
      Kimura Y, Sumi M, Sakihama N, Tanaka F, Takahashi H, Nakamura T
    • Journal Title

      cancer in the neck. AJNR Am J Neuroradiol 29

      Pages: 1355-1359

    • Related Report
      2008 Final Research Report
  • [Journal Article] MR factor analysis : improved technology for the assessment of 2D dynamic structures of benign and malignant salivary gland tumors2008

    • Author(s)
      Eida S, Ohki M, Sumi M, Yamada T, Nakamura T
    • Journal Title

      J Magn Reson Imaging 27

      Pages: 1256-1262

    • Related Report
      2008 Final Research Report
  • [Journal Article] Ionizing radiation induces macrophage foam cell formation and aggregation through JNK-dependent activation of CD36 scavenger receptors2008

    • Author(s)
      Katayama I, Hotokezaka Y, Matsuyama T, Sumi T, Nakamura T
    • Journal Title

      Int J Radiat Oncol Biol Phys 70

      Pages: 835-846

    • Related Report
      2008 Final Research Report
  • [Journal Article] Prevalence of Sjogrenos syndrome among Nagasaki atomic bomb survivors2008

    • Author(s)
      Hida A, Akahoshi M, Takagi Y, Ashizawa K, Imaizumi M, Soda M, Maeda R, Nakashima E, Ida H, Kawakami A, Nakamura T, Eguchi K
    • Journal Title

      Ann Rheum Dis. 67

      Pages: 689-695

    • Related Report
      2008 Final Research Report
  • [Journal Article] HTLV-I infection results in resistance toward salivary gland destruction of Sjogrenos syndrome2008

    • Author(s)
      Nakamura H, Kawakami A, Takagi Y, Nakamura T, Eguchi K
    • Journal Title

      Clin Exp Rheumatol 26

      Pages: 653-655

    • Related Report
      2008 Final Research Report
  • [Journal Article] Parotid irrigation and cevimeline gargle for the treatment of xerostomia in patients with or without Sjogrenos syndrome2008

    • Author(s)
      Takagi Y, Katayama I, Tashiro S, Nakamura T
    • Journal Title

      J Rheumatol 35

      Pages: 2289-91

    • Related Report
      2008 Final Research Report
  • [Journal Article] Apparent diffusion coefficient mapping of salivary gland tumors : prediction of benignancy and malignancy2008

    • Author(s)
      Eida S, Sumi M, Sakihama N, Takahashi H, Nakamura T
    • Journal Title

      JNR Am J Neuroradiol 28

      Pages: 116-121

    • Related Report
      2008 Final Research Report
  • [Journal Article] MR imaging of labial glands2008

    • Author(s)
      Sumi M, Yamada T, Takagi Y, Nakamura T
    • Journal Title

      AJNR Am J Neuroradiol 28

      Pages: 1552-1556

    • Related Report
      2008 Final Research Report
  • [Journal Article] MR imaging criteria for the prediction of extranodal spread of metastatio cancer in the neck.2008

    • Author(s)
      Kimura Y, Sumi M, Sakihama N, Tanaka F, Takahashi H, Nakamura T
    • Journal Title

      AJNR Am J Neuroradiol 29

      Pages: 1355-1359

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Balanced turbo field echo sequence of parotid gland diseases2007

    • Author(s)
      Sumi M, Van Cauteren M, Takagi Y, Nakamura T
    • Journal Title

      AJR 188

      Pages: 228-232

    • Related Report
      2008 Final Research Report
  • [Journal Article] Nodal imaging in the neck : recent advances in US2007

    • Author(s)
      Nakamura T, Sumi M
    • Journal Title

      CT and MR imaging in metastatic nodes (Review) Eur Radiol 17 17

      Pages: 1235-1241

    • Related Report
      2008 Final Research Report
  • [Journal Article] Parallel imaging technique for the external carotid artery and its branches : comparison of balanced turbo field echo, phase contrast, and time-of-flight sequences2007

    • Author(s)
      Sumi T, Sumi M, Van Cauteren M, Kimura Y, Nakamura T
    • Journal Title

      J Magn Reson Imaging 25

      Pages: 1028-1034

    • Related Report
      2008 Final Research Report
  • [Journal Article] Diagnostic ability of apparent diffusion coefficients for lymphomas and carcinomas in the pharynx2007

    • Author(s)
      Sumi M, Ichikawa Y, Nakamura T
    • Journal Title

      Eur Radiol 17

      Pages: 2631-2637

    • Related Report
      2008 Final Research Report
  • [Journal Article] Diagnostic performance of MR imaging relative to CT for metastatic nodes of head and neck squamous cell carcinomas2007

    • Author(s)
      Sumi M, Kimura Y, Sumi T, Nakamura T
    • Journal Title

      J Magn Reson Imaging 26

      Pages: 1626-1633

    • Related Report
      2008 Final Research Report
  • [Journal Article] Diagnostic performance of MRI relative to CT for metastatic nodes of head and neck squamous cell carcinoma2007

    • Author(s)
      Misa Sumi
    • Journal Title

      Journal of magnetic resonance imaging 26

      Pages: 1626-1633

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 頭頸部領域におけるADCの有用性2009

    • Author(s)
      角美佐
    • Organizer
      第28回日本画像医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-28
    • Related Report
      2008 Final Research Report
  • [Presentation] 頸部リンパ節の画像診断2008

    • Author(s)
      角美佐
    • Organizer
      第59回新潟画像医学研究会
    • Place of Presentation
      新潟
    • Year and Date
      2008-10-11
    • Related Report
      2008 Final Research Report
  • [Presentation] SENSE併用3D脂肪抑制TITFE (Iinear)法の頭頚部疾患への応用2008

    • Author(s)
      角美佐, 中村卓
    • Organizer
      第49回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-05-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 頭頸部への臨床応用2008

    • Author(s)
      角美佐
    • Organizer
      第13回Parallel imaging symposium
    • Place of Presentation
      東京(フィリップスエレクトロニクスジャパン主催)
    • Year and Date
      2008-03-22
    • Related Report
      2008 Final Research Report
  • [Presentation] SENSE併用3D脂肪抑制TITFE(linear)法の頭頸部疾患への応用2008

    • Author(s)
      角美佐、中村卓
    • Organizer
      第49回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] 耳下腺のT1、T2緩和時間2008

    • Author(s)
      佐々木美穂、角美佐、中村卓
    • Organizer
      第49回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] ADCを左右する因子について2008

    • Author(s)
      榮田智、佛坂由可、佐々木美穂、角美佐、山田敏郎、中村卓
    • Organizer
      第49回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Final Research Report
  • [Presentation] 超音波画像診断はシェーグレン症候群診断で唾液腺造影法にとってかわれるか2008

    • Author(s)
      高木幸則,佐々木美穂,角美佐,中村卓
    • Organizer
      第28回関西・九州合同地方会
    • Place of Presentation
      鹿児島
    • Related Report
      2008 Final Research Report
  • [Presentation] オーダリングシステム・PACS 立ち上げ奮戦記2008

    • Author(s)
      山田敏朗, 北森秀希, 角美佐, 中村卓
    • Organizer
      第28回関西・九州合同地方会
    • Place of Presentation
      鹿児島
    • Related Report
      2008 Final Research Report
  • [Presentation] 頭頸部領域における節性・節外性リンパ腫のMRイメージング2007

    • Author(s)
      角 美佐
    • Organizer
      日本歯科放射線学会 第12回臨床画像大会
    • Place of Presentation
      千葉県柏市
    • Year and Date
      2007-10-19
    • Related Report
      2007 Annual Research Report
  • [Presentation] 照射後唾液腺のADC2007

    • Author(s)
      木村泰男, 角美佐, 佐々木美穂, 中村卓
    • Organizer
      第12回臨床画像大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] 頭頸部領域における節性・節外性悪性リンパ腫のMRイメージング2007

    • Author(s)
      角美佐, 木村泰男, 角忠輝, 中村卓
    • Organizer
      第12回臨床画像大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] サウンド オブサイレンス2007

    • Author(s)
      中村卓, 角美佐
    • Organizer
      第12回臨床画像大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] 小さいものはどちらが得意2007

    • Author(s)
      市川陽子, 角美佐, 中村卓
    • Organizer
      第48回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      埼玉
    • Related Report
      2008 Final Research Report
  • [Presentation] バルジ大作戦2007

    • Author(s)
      角忠輝, 角美佐, 木村泰男, 中村卓
    • Organizer
      第48回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      埼玉
    • Related Report
      2008 Final Research Report
  • [Presentation] リンパ節転移の被膜外浸潤の進展範囲と予後2007

    • Author(s)
      木村泰男, 角美佐, 中村卓
    • Organizer
      第48回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      埼玉
    • Related Report
      2008 Final Research Report
  • [Presentation] 非扁平上皮癌頸部リンパ節転移2007

    • Author(s)
      佐々木美穂, 角美佐, 木村泰男, 高木幸則, 榮田智, 市川陽子, 角忠輝, 中村卓
    • Organizer
      第48回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      埼玉
    • Related Report
      2008 Final Research Report
  • [Presentation] 最新のMRI診断-悪性診断の進歩-2007

    • Author(s)
      角美佐
    • Organizer
      第61回NPO法人日本口腔科学会学術集会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Book] In Encyclopedia of diagnostic imaging. Baert AL ed. Springer2008

    • Author(s)
      Sumi M, Nakamura T
    • Publisher
      Lymphadenopathies, head and neck
    • Related Report
      2008 Final Research Report
  • [Book] In Encyclopedia of diagnostic imaging. Baert AL ed. Springer2008

    • Author(s)
      Sumi M, Nakamura T
    • Publisher
      Neoplasms, benign and malignant, salivary glands
    • Related Report
      2008 Final Research Report
  • [Book] In Cancer Imaging Vol. 2. Hayat MS ed. Elsevier2008

    • Author(s)
      Sumi M, Nakamura T
    • Publisher
      Benign and malignant nodes in the neck : Magnetic resonance microimaging
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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