| Project/Area Number |
19592225
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Tohoku University |
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Principal Investigator |
YOKOYAMA Masayoshi Tohoku University, 大学院・歯学研究科, 助教 (20396500)
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| Co-Investigator(Kenkyū-buntansha) |
SASAKI Keiichi 東北大学, 大学院・歯学研究科, 教授 (30178644)
KOYAMA Shigeto 東北大学, 病院, 准教授 (10225089)
SASAKI Hiroto 東北大学, 大学院・歯学研究科, 大学院非常勤講師 (60431582)
伊藤 正敏 東北大学, サイクロトロンRIセンター核医学研究部, 教授 (00125501)
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| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 骨代謝 / 有床義歯 / 骨シンチグラフィ / SPECT / 骨シンチグラフィー / 顎関節 |
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| Research Abstract |
This study aimed to reveal the dynamic change of bone metabolism under the denture base using SPECT. Wistar rats were anesthetized with pentobarbital and the right maxilla teeth were extracted. To observe the bone metabolic activity, SPECT of rat cranium was taken using a gamma-camera. Tc-99m-MDP (74MBq/rat) was injected intravenously. Although the SPECT images were lower quality than planer bone scitigram, quantitative analysis of the the images provided sufficient information to examine the bone metabolic activity of alveolar bone beneath the denture base.
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