Development of the crude drug combination oral moisture for dry mouth
| Project/Area Number |
19592238
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Hiroshima University |
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Principal Investigator |
KAGAWA Kazuko Hiroshima University, 病院, 助教 (60432671)
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| Co-Investigator(Kenkyū-buntansha) |
HONG Guang 東北大学, 大学院・歯学研究科, 助教 (70363083)
貞森 紳丞 広島大学, 大学院・医歯薬学総合研究科, 准教授 (40187167)
濱田 泰三 広島大学, 大学院・医歯薬学総合研究科, 教授 (50034244)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 口腔乾燥症 / 口腔内潤滑補助剤 / 生薬 / 潤滑補助剤 |
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| Research Abstract |
This research aimed at development of the crude drug combination oral moisture for dry mouth. The significant differences were found among different materials in initial viscocity and adhesive strength of oral moisture. The values of adhesive strength increased after immersing significantly in each material. And the crude drug influenced distribution of AQP5 in salivary duct membrane of parotid positively. The results was suggest that the development of the crude drug combination oral moisture for dry mouth is possible.
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Report
(4 results)
Research Products
(25 results)
