Fabrication of Bone Replacement Materials using Carbonate Apatite

• Project/Area Number: 19592243
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 補綴理工系歯学
• Research Institution: Yamaguchi University
• Principal Investigator: UDO Koichi Yamaguchi University, 大学院・理工学研究科, 准教授 (60145266)
• Co-Investigator(Kenkyū-buntansha): UEYAMA Yoshiya 山口大学, 大学院・医学研究院, 教授 (00168668)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2007: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 生体材料 / 骨補填材 / 炭酸アパタイト / フォーム / 3次元連通気孔 / 3元連通気孔

Research Abstract

本研究では、第一にリン酸三カルシウムのフォームを作成し、次に炭酸アンモニウム水溶液を用いて水熱処理する事によって3 次元連通気孔を有するウレタンフォームの形態を保ったまま炭酸アパタイトフォームを作成できることを明らかにした。また、水熱処理時に用いる炭酸アンモニウム水溶液の濃度を変えることで炭酸アパタイトフォームの炭酸基濃度を制御できることも明らかにした。

Research Products

• [Journal Article] Fabrication of low-crystallinity hydroxyapatite foam based on the setting reaction of a-tricalcium phosphate foam (2009)
  • Author(s): S. Karashima, A. Takeuchi, S.Matsuya, K. Udoh, K. Koyano, K.Ishikawa
  • Journal Title: Journal of Biomedical Materials Research A 88 Pages: 623-633
• [Journal Article] Fabrication of macroporous carbonate apatite foam by hydrothermal conversion of a-tricalcium phosphate in carbonate solutions (2009)
  • Author(s): H. Wakae
  • Journal Title: Journal of Biomedical Materials Research Part A 88A Pages: 957-963
  • Peer Reviewed
• [Journal Article] Fabrication of low-crystallinity hydroxyapatite foam based on the setting reaction of a-tricalcium phosphate foam (2009)
  • Author(s): S. Karashima
  • Journal Title: Journal of Biomedi cal Materials Research Part A 88A Pages: 628-633
  • Peer Reviewed
• [Journal Article] Fablication of macroporous carbonate apatite foam by hydrothermal conversion of a-tricalcium phosphate in carbonate solutions (2008)
  • Author(s): H. Wakae, A. Takeuchi, K. Udoh, S. Matsuya, M. Munar, R. Z LeGeros, A. Nakasima, K. Ishikawa
  • Journal Title: Journal of BiomedicalM aterials Research A 87(4) Pages: 957-963
• [Journal Article] Effects of hydrothermal treatment temperature on the crystallinity of Cancellous bone type carbonate apatite foam (2008)
  • Author(s): H. Wakae
  • Journal Title: Key Engineering Materials 361-363 Pages: 975-978
  • Peer Reviewed
• [Journal Article] Fabrication of porous low crystalline calcite block by carbonation of calcium hydroxide compact (2007)
  • Author(s): S. Matsuya, X. Lin, K. Udoh, MNakagawa, R. Shimogoryo, Y. Terada, K. Ishikawa
  • Journal Title: Journal of Materials Science : Materials in Medicine 18(7) Pages: 1361-7
• [Journal Article] Fabrication of porous low crystalline calcite block by carbonation of calcium hydroxide compact. (2007)
  • Author(s): S. Matsuya
  • Journal Title: Journal of Materials Science:Materials in Medicine 18 Pages: 1361-1367
  • Peer Reviewed