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Development of effective methods of the periodontal regeneration of cryopreserved teeth, for expansion of indications for tooth transplantation.

Research Project

Project/Area Number 19592287
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionNiigata University

Principal Investigator

泉 直也  Niigata University, 医歯学総合病院, 助教 (10361908)

Co-Investigator(Kenkyū-buntansha) 芳澤 享子  新潟大学, 医歯学総合研究科, 助教 (60303137)
小野 由起子  新潟大学, 医歯学総合病院, 助教 (80345511)
Co-Investigator(Renkei-kenkyūsha) 小野 由起子  新潟大学, 医歯学総合研究科, 助教 (80345511)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords歯の移植 / 凍結保存 / 歯根膜
Research Abstract

歯の移植の適応拡大のため、凍結保存歯の歯根膜を有効に再生させる方法を確立する目的で、ラット臼歯を抜歯後、凍結保存して解凍後に腹部皮膚に移植する実験系を作成した。凍結保存歯は解凍した後、一定期間器官培養して腹部皮下へ移植した。凍結保存歯は、即時移植した歯と比較して明確な歯根膜の再生能の改善は見いだされなかった。今後も培養法を改良し、凍結保存歯の器官培養の有効性および問題点を明らかにしていく予定である。

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (6 results)

All 2009 2008 2007

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (3 results)

  • [Journal Article] 残留嚢胞摘出と同時に歯の即時移植を行った1例2009

    • Author(s)
      安島久雄、芳澤享子、小野和宏、泉直也、新美奏恵、小山貴寛、菅井登志子、興地隆史、齊藤力、高木律男
    • Journal Title

      新潟歯学会雑誌 39(2)

      Pages: 53-58

    • NAID

      120006749428

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Periodontal regeneration of transplanted rat teeth subcutaneously after cryopreservation2007

    • Author(s)
      Naoya Izumi, Michiko Yoshizawa, Yukiko Ono, Tadaharu Kobayashi, Yoshioki Hamamoto, Chikara Saito
    • Journal Title

      Int. J. Oral Maxillofac. Surg 36(9)

      Pages: 838-844

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Periodontal regeneration of transplanted rat teeth subcutaneously after cryopreservation.2007

    • Author(s)
      Naoya Izumi
    • Journal Title

      Int. J. Oral Maxillofac. Surg. 36(9)

      Pages: 838-844

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 凍結保存歯の歯周組織を有効に再生させるための方法の検討2008

    • Author(s)
      泉直也、芳澤享子、齊藤力
    • Organizer
      第21日本歯科医学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-11-15
    • Related Report
      2009 Final Research Report
  • [Presentation] Tooth autotransplantion in combination with autologous platelet-rich plasma (PRP)2007

    • Author(s)
      Naoya Izumi, Michiko Yoshizawa, Yukiko Ono, Kanae Niimi, Toshiko Sugai, Chikara Saito
    • Organizer
      第1回日米韓顎顔面外科学合同学術大会
    • Place of Presentation
      ハワイ
    • Year and Date
      2007-10-11
    • Related Report
      2009 Final Research Report
  • [Presentation] 多血小板血漿(PRP)を併用した歯の自家移植2007

    • Author(s)
      泉直也、芳澤享子、小野由起子、新美奏恵、菅井登志子、齊藤力
    • Organizer
      第52日本口腔外科学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-09-29
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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