A clinical study to prove the effective evidence of bone substitutes/bone growth factors for bone graft and augmentation on the oral and maxillofacial bone
| Project/Area Number |
19592302
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
NISHIHARA Kazuhide Kagoshima University, 医学部・歯学部附属病院, 講師 (30253892)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Norifumi 鹿児島大学, 大学院・医歯学総合研究科, 教授 (60217875)
NOZOE Etsurou 鹿児島大学, 大学院・医歯学総合研究科, 准教授 (40208351)
TAMATSU Yuichi 鹿児島大学, 大学院・医歯学総合研究科, 准教授 (80266569)
MATSUYAMA Takashi 鹿児島大学, 医学部・歯学部附属病院, 准教授 (40253900)
YOSHIMOTO Takehiko 鹿児島大学, 医学部・歯学部附属病院, 助教 (60419653)
李 知午 鹿児島大学, 医学部・歯学部附属病院, 医員 (40404503)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 骨補填材 / β-TCP / ハイドロキシアパタイト / 骨造成術 / インプラント / 免疫組織学的 / 上顎洞底挙上術 / 人工骨骨補填材 / 骨増生手術 / β-TCP製人工骨補填材 / HA-β-TCP製人工骨補填材 |
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| Research Abstract |
The purpose of the present study was to evaluate the clinical usefulness of bone substitutes such as tri-calciumphoshate (B-TCP), hydroxyapatite (HA) and mixed bone material (B-TCP+HA) for bone grafting and sinus augmentation on oral and maxillofacial bone. The results of assessment of bone grafting on the limited bone volume owing to atrophy of the alveolar ridge and bone loss of postextraction was as follows. 1) excellent : 10 cases 2) good : 4 cases 3) poor : 4 cases 4) very poor : 1 case. In this "very poor case", the bone substitute block made by B-TCP+HA was removed because of bone infection after dental implant placement. The authors concluded that combined grafting with bone substitutes using the autogenous and B-TCP+HA granulation seems to be effective as a bone material against bone augmentation.
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Report
(4 results)
Research Products
(14 results)
