The molecular biological analysis of the involvement of HPV infection on the multiple cancer and the case of poor prognosis of early stage in oral cancer
| Project/Area Number |
19592304
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | University of the Ryukyus |
|---|
Principal Investigator |
SUNAGAWA Hajime University of the Ryukyus, 医学部, 教授 (30112452)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2008: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 口腔外科学一般 / HPV / Stage分類 / 癌浸潤様式 / 頸部リンパ節転移 / 扁平上皮癌 / タイプ別 / HeLa細胞 / IL-8 / 口腔扁平上皮癌 / 多発癌 / 早期癌予後不良症例 |
|---|
| Research Abstract |
We found that the ratio of HPV infection is higher in low grade than high grade of oral cancer. We studied the association of oral cancer biomarker IL-8 and HPV infection with molecular biological method. We found that HPV E6 protein regulates inflammation dependent IL-8 production.
|
Report
(4 results)
Research Products
(9 results)
