Experimental study on development and application in beagles with cleft lip/palate
| Project/Area Number |
19592326
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
FURUKAWA Hiroo Aichi Gakuin University, 心身科学部, 准教授 (70291763)
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| Co-Investigator(Kenkyū-buntansha) |
KOYASU Kazuhiro 愛知学院大学, 歯学部, 講師 (50183348)
NAITO Munetaka 愛知学院大学, 歯学部, 准教授 (20167539)
高橋 久英 藤田保健衛生大学, 衛生学部, 教授 (80084606)
豊田 哲郎 愛知学院大学, 心身科学部, 准教授 (10308786)
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| Project Period (FY) |
2007 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | イヌ / ヒト / 先天異常 / 口唇裂 / 口蓋裂 / 心臓異常 / 大血管異常 / 疾患モデル動物 |
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| Research Abstract |
The Jpanese breeder network of the beagle was able to be established in the first year. We obtained jaw deformity beagles (for breeding , by two male females) using the network. Aiming at the establishment of the cleft lip and palate natural occurrence beagle system, we tried them as a mating individual. From a reason peculiar to an individual, however, do not readily become pregnant, we were not able to acquire a second cleft lip/palate beagle or jaw deformity beagle.
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Report
(6 results)
Research Products
(9 results)
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[Journal Article] Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.2009
Author(s)
Suzuki S, Marazita ML, Cooper ME, Miwa N, Hing A, Jugessur A, Natsume N, Shimozato K, Ohbayashi N, Suzuki Y, Niimi T, Minami K, Yamamoto M, Altannamar TJ, Erkhembaatar T, Furukawa H, Daack-Hirsch S, L'heureux J, Brandon CA, Weinberg SM, Neiswanger K, Deleyiannis FW, de Salamanca JE, Vieira AR, Lidral AC, Martin JF, Murray JC.
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Journal Title
Am J Hum Genet. 84(3)(Epub 2009 Feb 26)
Pages: 406-11
Related Report
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