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Development of a novel zinc releasing cement by conversions of zinc phosphate into zinc calcium phosphate

Research Project

Project/Area Number 19592355
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

HORIUCHI SHINYA  The University of Tokushima, 医学部・歯学部附属病院, 助教 (70263861)

Co-Investigator(Kenkyū-buntansha) TSUJI Keiko  徳島大学, 医学部・歯学部附属病院, 医員 (80380096)
IZAWA Takashi  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (30380017)
FUJIHARA Shinji  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (70403706)
TANAKA Eiji  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (40273693)
KINOUCHI Nao  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (30457329)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords亜鉛 / ハイドロキシアパタイト / 骨形成 / セメント / リン酸亜鉛 / 硝酸カルシウム / 人工骨置換材
Research Abstract

Zinc releasing apatite cement was developed from zinc calcium phosphate derived from zinc phosphate, introduced into apatite cement. The proliferations of osteoblastic-cells and alkaline phosphatase activities were enhanced when the cells were cultured on this cement. It is suggested that this novel cement potent promotive effect as the bone cement.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (11 results)

All 2009 2008 2007

All Journal Article (8 results) (of which Peer Reviewed: 7 results) Presentation (3 results)

  • [Journal Article] 過去10年間に徳島大学病院矯正歯科を受診した顎顔面骨折患者の実態調査2009

    • Author(s)
      冨田優子, 堀内信也, 田中栄二, 他(6人中2番目)
    • Journal Title

      中・四国矯正歯科学会雑誌 21

      Pages: 71-75

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enamel bonding of self-etching and phosphoric acid-etching orthodontic adhesives in simulating clinical conditions: Debonding force and enamel surface.2009

    • Author(s)
      Horiuchi S, Kaneko K, Asaoka A, Tanaka E, et. al.
    • Journal Title

      Dental materials journal 28

      Pages: 419-425

    • NAID

      10025915975

    • Related Report
      2009 Final Research Report
  • [Journal Article] Development of a novel cement by conversion of hopeite in set zinc phosphate cement into biocompatible apatite.2009

    • Author(s)
      Horiuchi S, Asaoka K, Tanaka E
    • Journal Title

      Bio-medical Materials and Engineering 19

      Pages: 121-131

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel cement by conversion of hopeite in set zinc phosphate cement into biocompatible apatite.2009

    • Author(s)
      Horiuchi S, et al.
    • Journal Title

      Bio-medical Materials and Engineering 19

      Pages: 121-131

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enamel bonding of self-etching and phosphoric acid-etching orthodontic adhesives in simulating clinical conditions : Debonding force and enamel surface2009

    • Author(s)
      Shinya Horiuchi, et al.
    • Journal Title

      Dental materials journal 28

      Pages: 419-425

    • NAID

      10025915975

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel cement by conversion of hopeite in set zinc phosphate cement into biocompatible apatite.2009

    • Author(s)
      Horiuchi S
    • Journal Title

      Bio-medical Materials and Engineering (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enamel bonding of self-etching and phosphoric acid-etching orthodontic adhesives in simulating clinical conditions : Debonding force and enamel surface2009

    • Author(s)
      Shinya Horiuchi
    • Journal Title

      Dental materials journal (in press)

    • NAID

      10025915975

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上下顎移動術を行った顎偏位を伴う下顎前突の1治験例2007

    • Author(s)
      内田 玲子
    • Journal Title

      中・四国矯正歯科学会雑誌 19

      Pages: 29-36

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 上顎縦骨折による咬合不全に対し、急速拡大装置を逆回転することで整復した1例2009

    • Author(s)
      松田りえ, 堀内信也, 田中栄二, 他(6人中2番目)
    • Organizer
      中・四国矯正歯科学会
    • Place of Presentation
      徳島市
    • Year and Date
      2009-07-04
    • Related Report
      2009 Final Research Report
  • [Presentation] DEVELOPMENT OF NOVEL BIOCERAMIC BY MODIFICATION OF ZINC PHOSPHATE CEMENT2009

    • Author(s)
      S. HORIUCHI, K. ASAOKA, T. IZAWA, S. FUJIHARA, N. KINOUCHI, S. KURODA, E. TANAKA
    • Organizer
      International associations of dental research
    • Place of Presentation
      Miami (USA)
    • Year and Date
      2009-04-01
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 水硬性リン酸亜鉛セメントのアパタイト置換を応用した新しいバイオマテリアルの開発2008

    • Author(s)
      堀内信也, 日浅雅博, 川上恵美, 藤原慎視浅岡憲三, 田中栄二
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      幕張
    • Related Report
      2009 Final Research Report 2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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