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Gene expression profile of the cartilage of mandible and the growth palate of tibia during growth period

Research Project

Project/Area Number 19592373
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTsurumi University

Principal Investigator

NAKAMURA Yoshiki  Tsurumi University, 歯学部, 教授 (10097321)

Co-Investigator(Kenkyū-buntansha) 野田 晃司  鶴見大学, 歯学部, 講師 (10148059)
及川 崇  鶴見大学, 歯学部, 助教 (60386919)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords下顎頭軟骨 / 脛骨骨端軟骨 / 遺伝子解析 / 網羅的解析 / 成長期 / 骨端軟骨 / 軟骨性成長 / 遺伝子発現 / 静止層 / 増殖層 / 肥大層 / 下顎頭軟骨組織 / 骨端軟骨組織 / 発現遺伝子 / maicroarray
Research Abstract

今回、我々は下顎頭軟骨と長管骨の骨端軟骨には本質的な違いがあるのかを明らかにするために、両軟骨組織に発現している遺伝子を解析することを目的とした。すなわち、成長期にある下顎頭軟骨と長管骨骨端軟骨の発現遺伝子を網羅的に解析し、それぞれの発現遺伝子の違いを検討した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (28 results)

All 2008 2007 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (13 results)

  • [Journal Article] Orthodontic Treatment for Oral Rehabilitation after Multiple Maxillofacial Bone Fracture2008

    • Author(s)
      Nakamura Y, Ogino T, Hirashita A
    • Journal Title

      Amer J Orthod & Dentofac Orthop 134

      Pages: 447-455

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time-lapse observation of rat periodontal ligament during function and tooth movement using micro-computed tomography2008

    • Author(s)
      Nakamura Y, Noda K, Shimoda S, Oikawa T, Arai C, Nomura Y and Kawasaki K
    • Journal Title

      European J Orthod 30

      Pages: 320-326

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of risk factors for dental caries from 6 to 8 years old children2008

    • Author(s)
      Katsumura S, Nishikawara F, Tamaki Y, Yamada H, Nakamura Y, Sato K, Tsuge S, Nomura Y , Hanada N
    • Journal Title

      Pediatlic Dental Journal Vol.18, No.1

    • NAID

      10024180134

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time-lapse observation of rat periodontal ligament during function and tooth movement using micro-computed tomography2008

    • Author(s)
      Nakamura Y, Noda K, Shimoda S, Oikawa T, et al.
    • Journal Title

      European J Orthodontics 30

      Pages: 320-326

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A randomized controlled trial by the 3DS dental caries2007

    • Author(s)
      Katsumura S, Nishikawara F, Tamaki Y, Nakamura Y, Sato K, Nomura Y, Hanada N
    • Journal Title

      ediatric Dental Journal 17

      Pages: 1-7

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 骨格性下顎前突症のおける外科的矯正治療後の軟組織側貌の予測2007

    • Author(s)
      飛田康平、関谷利子、常盤肇、中村芳樹
    • Journal Title

      Orthodontic wave-Japanese Edition 66

      Pages: 72-80

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A new idea and method of tooth movement using a ratchet bracket2007

    • Author(s)
      Noda K, Nakamura Y, Shimpo S, Oikawa T
    • Journal Title

      European J Orthod 29

      Pages: 225-231

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laser capture microdissection of rat periodontal ligament for gene analysis2007

    • Author(s)
      Y Nakamau, Y Nomura, et. al.
    • Journal Title

      Biotechnic and Histochemistry 82

      Pages: 295-300

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Elimination of transverse dental compensation is critical for treatment of patients with severe facial asymmetry

    • Author(s)
      Sekiya T, Nakamura Y, Oikawa T, et.al.
    • Journal Title

      Amer J Orthod & Dentofac Orthop (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of asymmetry of lip in orthognathic surgery patients

    • Author(s)
      Yamashita Y, Nakamura Y, et.al.
    • Journal Title

      Amer J Orthod Dentfac Orthop (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laser capture microdissection of rat periodontal ligament for gene analysis

    • Author(s)
      Yoshiki Nakamura, Yoshiaki Nomura, Chihiro Arai, Koji Noda, Takashi Oikawa, Kyotaro Kogure, Tadafumi Kawamoto, Nobuhiro Hanada
    • Journal Title

      Biotechnic and Histochemistry (In press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Morphological changes in the rat periodontal ligament and its vascularity after experimental tooth movement using super elastic forces

    • Author(s)
      Noda K, Nakamura Y, Kogure K, Nomura Y
    • Journal Title

      European J Orthodontics (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of asymmetry of lip in orthognathic surgery patient

    • Author(s)
      Yamashita Y, Nakamura Y, Shimada T, Hirashita A
    • Journal Title

      American J orthodontics and dentofacial orthopedics (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time・lapse observation of rat periodontal ligament during function and tooth movement using micro・computed tomography

    • Author(s)
      Y Nakamura, K Noda, et. al.
    • Journal Title

      European Journal of Orthodontics (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of asymmetry of lip in orthognathic surgery patients

    • Author(s)
      Y Yamashita, Y Nakamura, et. al.
    • Journal Title

      America Journal of Orthodontists (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 成長期における下顎頭軟骨と脛骨骨端軟骨の発現遺伝子の網羅的解析2008

    • Author(s)
      宮本豊, 中村芳樹, 新井千博, 及川 崇, 野田晃司, 野村義明, 花田信弘
    • Organizer
      日本矯正歯科学会
    • Place of Presentation
      千 葉 市
    • Year and Date
      2008-09-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] Time-lapse observation of rat PDL during tooth movement with micro-CT2008

    • Author(s)
      Nakamura Y, Arai C., et.al.
    • Organizer
      84 Congress of the European Orthodontic Society
    • Place of Presentation
      Lisbon, Portogal
    • Related Report
      2008 Final Research Report
  • [Presentation] Changes in rat periodontal ligamentand its vascularity by super elastic force2008

    • Author(s)
      Noda K, Nakamura Y, et.al.
    • Organizer
      84 Congress of the European Orthodontic Society
    • Place of Presentation
      Lisbon, Portogal Lisbon, Portogal
    • Related Report
      2008 Final Research Report
  • [Presentation] Gene expression profile of periodontal ligament and gingival connective tissue2008

    • Author(s)
      Oikawa T, Nakamura Y, et.al.
    • Organizer
      84 Congress of the European Orthodontic Society
    • Place of Presentation
      Lisbon, Portogal Lisbon, Portogal
    • Related Report
      2008 Final Research Report
  • [Presentation] Microarray analysis of the PDL during tooth movement2008

    • Author(s)
      Arai C, Nakamura Y, et.al.
    • Organizer
      84 Congress of the European Orthodontic Society
    • Place of Presentation
      Lisbon, Portogal Lisbon, Portogal
    • Related Report
      2008 Final Research Report
  • [Presentation] 成長期における下顎頭軟骨と脛骨骨端軟骨の発現遺伝子の網羅的解析2008

    • Author(s)
      宮本豊、中村芳樹, 他
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] ラット歯根膜および歯肉の結合組織の遺伝子発現の比較検討2008

    • Author(s)
      及川崇、中村芳樹、他
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] 断続的な矯正力を繰り返し用いたさいのラット歯根膜組織の形態的変化の観察2008

    • Author(s)
      小暮杏太郎、野田晃司、中村芳樹, 他
    • Organizer
      第67回日本矯正歯科学会
    • Place of Presentation
      千葉
    • Related Report
      2008 Final Research Report
  • [Presentation] ラット歯根膜細胞のlaser microdissectionによるm-RNAの解析2007

    • Author(s)
      中村芳樹、及川崇、野田晃司、平下斐雄
    • Organizer
      第46回歯科基礎医学会
    • Place of Presentation
      広島
    • Related Report
      2008 Final Research Report
  • [Presentation] 歯を移動した際の発現遺伝子の解析、その1圧迫側歯根膜2007

    • Author(s)
      及川崇、中村芳樹, その他
    • Organizer
      第66回日本矯正歯科学会
    • Place of Presentation
      大阪
    • Related Report
      2008 Final Research Report
  • [Presentation] 歯を移動した際の発現遺伝子の解析、その2牽引側歯根膜2007

    • Author(s)
      新井千博、中村芳樹、その他
    • Organizer
      第66回日本矯正歯科学会
    • Place of Presentation
      大阪
    • Related Report
      2008 Final Research Report
  • [Presentation] Microarray analisis of the PDL during tooth movement in rat2007

    • Author(s)
      C Arai, Y Nakamura, et. al.
    • Organizer
      Japanese Association for Dental Research
    • Place of Presentation
      横浜市
    • Related Report
      2007 Annual Research Report
  • [Presentation] Microarray analysis of the PDL during tooth movement in rat, Japanese association for Dental Research

    • Author(s)
      Arai T, Nakamura Y., et.al.
    • Organizer
      55^<th> annual meeting
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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