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Studies on the etiological relationship between periodontitis and life-style related diseases

Research Project

Project/Area Number 19592398
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Periodontal dentistry
Research InstitutionOsaka Dental University

Principal Investigator

DOMAE Naochika  Osaka Dental University, 歯学部, 教授 (60115889)

Co-Investigator(Kenkyū-buntansha) UEDA Masatoshi  大阪歯科大, 歯学部, 教授 (00067117)
MASAKI Kambara  大阪歯科大, 歯学部, 教授 (90103085)
NAGANO Yutaka  大阪歯科大, 歯学部, 講師 (80228048)
MIYAMAE Masami  大阪歯科大, 歯学部, 講師 (20298821)
SAWAI Hirofumi  大阪歯科大学, 歯学部, 助教 (40298823)
GODA Seiji  大阪歯科大, 歯学部, 講師 (70351476)
INOUE Hiroshi  大阪歯科大, 歯学部, 講師 (10330143)
三宅 達郎  大阪歯科大学, 歯学部, 准教授 (40200141)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2007: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords歯周病 / メタボリック シンドローム / シグナル伝達 / 歯学 / 内科 / メタボリックシンドローム
Research Abstract

歯周病の発症および進展における免疫担当細胞の活性化と、それら細胞と血管内皮細胞との接着機構の一部を解明した。歯周病と虚血性心疾患および糖尿病や骨粗鬆症などの全身性疾患との双方向性発症関係を臨床医学的に検討した。歯周病有所見者は男性に多く、高年齢、高血圧、肥満および血清尿酸、γGTP、中性脂肪、 低比重コレステロール値/高比重コレステロール値比、血清アディポネクチン濃度の高値に有意の相関が見られた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (58 results)

All 2009 2008 2007

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (41 results)

  • [Journal Article] Differential roles for Bak in triton X-100- and deoxycholate- induced apoptosis2009

    • Author(s)
      SAWAI H, DOMAE N
    • Journal Title

      Biochem Biophys Res Commun 378

      Pages: 529-533

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Induction of osteoclast differentiation by NOC-18, a long- acting nitric oxide donor2009

    • Author(s)
      INAMI K, SAWAI H, YAKUSHIJI K, DOMAE N, MASTUMOTO N
    • Journal Title

      Orthodont Waves 68

      Pages: 20-27

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential roles for Bak in triton X-100- and deoxycholate-induced apoptosis.2009

    • Author(s)
      Sawai H.
    • Journal Title

      Biochem Biophys Res Commun 378

      Pages: 529-533

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Induction of osteoclast differentiation by NOC-18, a long-acting nitric oxide donor.2009

    • Author(s)
      Inami K.
    • Journal Title

      Orthodont Waves 68

      Pages: 20-27

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts2008

    • Author(s)
      KANEDA K, MIYAMAE M, SUGIOKA S, OKUSA C, INAMURA Y, DOMAE N, KOTANI J, FIGUEREDO VM
    • Journal Title

      Anesth Analg 106

      Pages: 9-16

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Release of cytochrome c from mitochondria precedes Bax translocation/activation in Triton X-100-induced apoptosis2008

    • Author(s)
      SAWAI H, DOMAE N.
    • Journal Title

      Leuk Res 32

      Pages: 445-453

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Emdogain stimulates matrix degra dation by osteoblasts2008

    • Author(s)
      GODA S, INOUE H, KANESHITA Y, NAGANO Y, IKEO T, IIDA J, DOMAE N
    • Journal Title

      J Dent Res 87

      Pages: 782-787

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Augmentation of TNF- induced osteoclast differentiation by inhibition of ERK and activation of p38 : Similar intracellular signaling between RANKL- and TNF-induced osteoclast differentiation2008

    • Author(s)
      INAMI K, SAWAI H, YAKUSHIJI K, KATAO Y, MASTUMOTO N, DOMAE N
    • Journal Title

      Orthodont Waves 67

      Pages: 150-156

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial K_<ATP> channels, and nitric oxide synthase, in guinea pig hearts.2008

    • Author(s)
      Kaneda K.
    • Journal Title

      Aneth Analg 106

      Pages: 9-16

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Release of cytochrome c from mitochondria precedes Bax translocation/activation in Triton X-100-induced apoptosis.2008

    • Author(s)
      Sawai H.
    • Journal Title

      Leuk Res 32

      Pages: 445-453

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Emdogain stimulates matrix degradation by osteoblasts.2008

    • Author(s)
      Goda S.
    • Journal Title

      J Dent Res 87

      Pages: 782-787

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Augmentation of TNF-induced osteoclast differentiation by inhibition of ERK and activat in of p38 : Similar intracellular singaling between RANKL- and TNF-induced osteoclast differentiation.2008

    • Author(s)
      Inami K.
    • Journal Title

      Orthodont Waves 67

      Pages: 150-156

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of matrix metalloproteinase-9 on the differentiation into osteo clast cells on RAW264 cells2008

    • Author(s)
      KANESHITA Y.
    • Journal Title

      Orthodont Waves 66

      Pages: 122-128

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Release of cytochrome c from mitochondria precedes Baxtranslocation/activation in Triton X-100-induced apoptosis2008

    • Author(s)
      SAWAI H.
    • Journal Title

      Leuk Res 32

      Pages: 445-453

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] P-selectin glycoprotein ligand-1 mediates L-selectin -independent leukocyte rolling in high endothelial venules of peripheral lymph nodes2007

    • Author(s)
      HARAKAWA N,SHIGETA A,WATO M,MERRILL-SKOLOFF G,FURIE BC,FURIE B,OKAZAKI T,DOMAE N,MIYASAKA M,HIRATA T
    • Journal Title

      Int Immunol 19

      Pages: 321-329

    • NAID

      10020111395

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effect of matrix metallo- proteinase-9 on the differentiation into osteoclast cells on RAW264 cells2007

    • Author(s)
      KANESHITA Y, GODA S,KAWAMOTO T.
    • Journal Title

      Orthodont Waves 66

      Pages: 122-128

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes2007

    • Author(s)
      HARAKAWA N.
    • Journal Title

      Int Immunol 19

      Pages: 321-329

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 単球系細胞のマクロファージ化に伴うosteoprogerin mRNAの誘導2008

    • Author(s)
      能登原靖宏,長野 豊,堂前尚親,上田雅俊
    • Organizer
      第516回大阪歯科学会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-12-13
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] セボフルランによるプレコンディショニングの心筋保護は、虚血再濯流後のExtracellular signal-regulated kinaseの活性化が必要である2008

    • Author(s)
      大草知佳
    • Organizer
      第516回大阪歯科学会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-12-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] Persistent cardioprotection by regular ethanol consumption after abstention depends on eNOS but not iNOS activity after reperfusion2008

    • Author(s)
      22KANEDA K, MIYAMAE M, SUGIOKA S, OKUSA C, INAMURA Y, ONISHI A, DOMAE N, FIGUEREDO V
    • Organizer
      American Heart Association Scientific Session 2008
    • Place of Presentation
      New Orleans
    • Year and Date
      2008-10-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Persistent cardioprotection by regular ethanol consumption after abstention depends on eNOS but not iNOS activity after reperfusion.2008

    • Author(s)
      Kaneda K.
    • Organizer
      American Heart Association Scientific Session 2008
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2008-10-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] アプロチニンは虚血再灌流後のPKCδ, GSK3βのリン酸化を阻害し、セボフルランによる心筋ポストコンディショニングを消失させる2008

    • Author(s)
      稲村吉高,宮前雅見,杉岡伸悟, 金田一弘,大草知佳,大西杏奈, 堂前尚親,小谷順一郎
    • Organizer
      第36回日本 歯科麻酔学会総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Final Research Report
  • [Presentation] 慢性エタノール摂取による心筋プレコンディショニング効果は再灌流後のnitric oxide synthase阻害により消失 する2008

    • Author(s)
      金田一弘,宮前雅見,杉岡伸悟, 大草知佳,稲村吉高,大西杏奈, 堂前尚親,小谷順一郎
    • Organizer
      第36回日本歯科麻酔学会 総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Final Research Report
  • [Presentation] 1MACセボフルランによるプレコンディショニングのmemoryには、PKCα,εの細胞膜へのtranslocationを要するが、PKCδ は必要としない2008

    • Author(s)
      大草知佳,宮前雅見,杉岡伸悟, 金田一弘,稲村吉高,大西杏奈, 堂前尚親,小谷順一郎
    • Organizer
      第36回 日本歯科麻酔学会総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Final Research Report
  • [Presentation] アプロチニンは虚血再潅流後のPKC5, GSK3Pのリン酸化を阻害し、セボフルランによる心筋ポストコンディショニングを消失させる2008

    • Author(s)
      稲村吉高
    • Organizer
      第36回日本歯科麻酔学会総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] 慢性エタノール摂取による心筋プレコンデイショニング効果は再潅流後のnitric oxide synthase阻害により消失する2008

    • Author(s)
      金田一弘
    • Organizer
      第36回日本歯科麻酔学会総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] 1MACセボフルランによるプレコンディショニングのmemoryには、PKCα, εの細胞膜へのtranslocationを要するが、PKCδは必要としない2008

    • Author(s)
      大草知佳
    • Organizer
      第36回日本歯科麻酔学会総会・学術集会
    • Place of Presentation
      大阪府
    • Year and Date
      2008-10-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] ケモカイン 刺激NK細胞におけるMatrix metalloproteinase-1の発現に ついて2008

    • Author(s)
      井上 博,合田征司,池尾 隆, 堂前尚親,西川泰央
    • Organizer
      第50回日本歯科基礎 医学会
    • Place of Presentation
      東京都
    • Year and Date
      2008-09-25
    • Related Report
      2008 Final Research Report
  • [Presentation] ケモカイン刺激NK細胞におけるMatrix metalloproteinase-1の発現について2008

    • Author(s)
      井上博
    • Organizer
      第50回日本歯科基礎医学会
    • Place of Presentation
      東京都
    • Year and Date
      2008-09-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] 長時間作用型NO供与体(NOC-18)による破骨 細胞分化誘導2008

    • Author(s)
      居波 薫,澤井宏文,藥師寺健太郎,堂前尚親,松本尚之
    • Organizer
      第67回日本矯正 歯科学会大会
    • Place of Presentation
      東京都
    • Year and Date
      2008-09-18
    • Related Report
      2008 Final Research Report
  • [Presentation] 破骨細胞分化におけるエストロゲンの役割2008

    • Author(s)
      片尾祐子,澤井宏文,居波 薫, 堂前尚親,松本尚之
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      東京都
    • Year and Date
      2008-09-18
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 長時間作用型NO供与体(NOC-18)による破骨細胞分化誘導2008

    • Author(s)
      居波薫
    • Organizer
      第67回日本矯正歯科学会大会
    • Place of Presentation
      東京都
    • Year and Date
      2008-09-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Osteoprotegerin is induced during differentiation of monocytes2008

    • Author(s)
      NOTOHARA Y, NAGANO Y, DOMAE N, UEDA M
    • Organizer
      The AAP 94^<th> Annual Meeting
    • Place of Presentation
      Seattle
    • Year and Date
      2008-09-08
    • Related Report
      2008 Final Research Report
  • [Presentation] 動脈硬化の危険因子と歯周状態との関連2008

    • Author(s)
      長野 豊,有城久美子,藥師寺 健太郎,能登原靖宏,上田雅俊, 三宅達郎,神原正樹,堂前尚親
    • Organizer
      第40回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      茨城県
    • Year and Date
      2008-07-10
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] セボフルランによる 心筋ポストコンディショニング 効果はアプロチニンにより消失 する2008

    • Author(s)
      稲村吉高,宮前雅見,杉岡伸悟, 金田一弘,大草知佳,堂前尚親, 小谷順一郎
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Final Research Report
  • [Presentation] 1MACセボフルラン 投与後の心筋細胞内εPKCの細胞膜へのtranslocationは30分以上持続し60分以内に停止する.2008

    • Author(s)
      大草知佳,宮前雅見,杉岡伸悟, 金田一弘,稲村吉高,堂前尚親, 小谷順一郎
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Final Research Report
  • [Presentation] .慢性エタノール摂取による心筋プレコンディショニング効果は再灌流後のnitric oxide synthase阻害により消失する2008

    • Author(s)
      金田一弘,宮前雅見,杉岡伸悟, 大草知佳,稲村吉高,堂前尚親, 小谷順一郎
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Final Research Report
  • [Presentation] セボフルランによる心筋ポストコンディショニング効果はアプロチニンにより消失する2008

    • Author(s)
      稲村吉高
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 1MACセボフルラン投与後の心筋細胞内εPKCの細胞膜へのtranslocationは30分以上持続し60分以内に停止する2008

    • Author(s)
      大草知佳
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 慢性エタノール摂取による心筋プレコンデイショニング効果は再濯流後のnitric oxide synthase阻害により消失する2008

    • Author(s)
      金田一弘
    • Organizer
      日本麻酔科学会第55回学術集会
    • Place of Presentation
      神奈川県
    • Year and Date
      2008-06-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] ゼラチナーゼが破骨細胞分化に およぼす影響2008

    • Author(s)
      池野真紀,合田征司,堂前尚親
    • Organizer
      第8回日本抗加齢 医学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2008-06-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Lipid raftsが破骨細胞分化に及ぼす影響2008

    • Author(s)
      合田征司,池野真紀,池尾 隆, 堂前尚親
    • Organizer
      第8回日本抗 加齢医学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2008-06-06
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼラチナーゼが破骨細胞分化におよぼす影響2008

    • Author(s)
      池野真紀
    • Organizer
      第8回日本抗加齢医学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Lipid raftsが破骨細胞分化に及ぼす影響2008

    • Author(s)
      合田征司
    • Organizer
      第8回日本抗加齢医学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] THP-1細胞のマクロ ファージ化に伴うosteoprotegerin mRNAの誘導2008

    • Author(s)
      能登原靖宏,長野 豊,堂前尚親,上田雅俊
    • Organizer
      .日本歯周病学会2008春季学術大会(第51回)
    • Place of Presentation
      埼玉県
    • Year and Date
      2008-04-25
    • Related Report
      2008 Final Research Report
  • [Presentation] NK細胞のI型コラーゲンに対する浸潤と分解について2008

    • Author(s)
      井上 博,合田征司,金下祐己, 松本尚之,池尾 隆,堂前尚親
    • Organizer
      日本歯周病学会2008春季学術大会(第51回)
    • Place of Presentation
      埼玉県
    • Year and Date
      2008-04-25
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] THP-1細胞のマクロファージ化に伴うosteoprotegerin mRNAの誘導2008

    • Author(s)
      能登原 靖宏
    • Organizer
      日本歯周病学会2008春季学術大会(第51回)
    • Place of Presentation
      埼玉県
    • Year and Date
      2008-04-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Matrix metallo- proteinase-1(MMP-1)andα2-integrin on the surface of NK3.3 cells stimulated by CXCL122008

    • Author(s)
      INOUE H, DOMAE N, NISHIKAWA Y
    • Organizer
      第85回 日本生理学会大会
    • Place of Presentation
      東京都
    • Year and Date
      2008-03-27
    • Related Report
      2008 Final Research Report
  • [Presentation] 一酸化窒素による破骨細胞分化誘導におけるMAPキナーゼの関与について2007

    • Author(s)
      居波 薫,澤井宏文,藥師寺健太郎, 片尾祐子,神原敏之,堂前尚親
    • Organizer
      第66回日本矯正歯科学会大会
    • Place of Presentation
      大阪府
    • Year and Date
      2007-09-20
    • Related Report
      2008 Final Research Report
  • [Presentation] 一酸化窒素による破骨細胞分化誘導におけるMAPキナーゼの関与について2007

    • Author(s)
      居波 薫
    • Organizer
      第66回日本矯正歯科学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2007-09-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Enamel matrix derivatives timulates matrix degradation by osteoclast2007

    • Author(s)
      GODA S, DOMAE E,OGAWA Y,TAKEUCHI O,YOSHIKAWA Y,TAMURA I,KAMADA A,DOMAE N,IKEO T
    • Organizer
      37^<th> Swiss Society of Periodontology / 11^<th> International Academy of Periodontology Congress 2007
    • Place of Presentation
      Swiss
    • Year and Date
      2007-09-13
    • Related Report
      2008 Final Research Report
  • [Presentation] Enamel matrix derivative stimulates matrix degradation by osteoclast2007

    • Author(s)
      Goda S.
    • Organizer
      37th Swiss Society of Periodontology/11th International Academy of Periodontology Congress 2007
    • Place of Presentation
      スイス
    • Year and Date
      2007-09-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] CXCL12刺激NK 細胞における細胞膜上のMatrix metalloproteinase-1 (MMP-1)とα2- Integrinの局在について2007

    • Author(s)
      井上 博,合田征司,池尾 隆,堂前 尚親,西川泰央
    • Organizer
      .第49回日本歯科基礎医学会
    • Place of Presentation
      北海道
    • Year and Date
      2007-08-29
    • Related Report
      2008 Final Research Report
  • [Presentation] CXCL12刺激NK細胞における細胞膜上のMatrix metalloproteinase-1 (MMP-1)とα2-Integrinの局在について2007

    • Author(s)
      井上 博
    • Organizer
      第49回日本歯科基礎医学会
    • Place of Presentation
      北海道
    • Year and Date
      2007-08-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] Involvement of signal pathway in osteoclast differentiation induced by TNF-alpha2007

    • Author(s)
      INAMI K, SAWAI H, YAKUSHIJI K, KAMBARA T, DOMAE N
    • Organizer
      83^<nd> Congress of the European Orthodontics Society
    • Place of Presentation
      Berlin
    • Year and Date
      2007-06-22
    • Related Report
      2008 Final Research Report
  • [Presentation] Involvement of signal pathway in osteoclast differentiation in duced by TNF-alpha2007

    • Author(s)
      INAMI K.
    • Organizer
      83nd Congress of the European Orthodontics Society
    • Place of Presentation
      ベルリン
    • Year and Date
      2007-06-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] アスピリンはMAPKを介してRANKLによるRAWの破骨細胞様細胞への分化を促進する2007

    • Author(s)
      薬師寺健太郎,澤井宏文,居波 薫, 神原正樹,堂前尚親
    • Organizer
      2007日本歯周病学会春季学術大会 (第50回)
    • Place of Presentation
      神奈川県
    • Year and Date
      2007-05-17
    • Related Report
      2008 Final Research Report
  • [Presentation] アスピリンはMAPKを介してRANKLによるRAWの破骨細胞様細胞への分化を促進する2007

    • Author(s)
      薬師寺 健太郎
    • Organizer
      2007日本歯周病学会春季学術大会(第50回)
    • Place of Presentation
      神奈川
    • Year and Date
      2007-05-17
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2017-10-19  

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