Molecular mechanisms of plant immunity and its suppression by pathogens

• Project/Area Number: 19678001
• Research Category: Grant-in-Aid for Young Scientists (S)
• Allocation Type: Single-year Grants
• Research Field: Plant pathology
• Research Institution: The Institute of Physical and Chemical Research
• Principal Investigator: SHIRASU Ken 独立行政法人理化学研究所, 植物免疫研究グループ, グループディレクター (20425630)
• Project Period (FY): 2007 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥114,530,000 (Direct Cost: ¥88,100,000、Indirect Cost: ¥26,430,000); Fiscal Year 2011: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000); Fiscal Year 2010: ¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000); Fiscal Year 2009: ¥27,430,000 (Direct Cost: ¥21,100,000、Indirect Cost: ¥6,330,000); Fiscal Year 2008: ¥39,000,000 (Direct Cost: ¥30,000,000、Indirect Cost: ¥9,000,000); Fiscal Year 2007: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
• Keywords: 遺伝子 / ゲノム / シグナル伝達 / 植物 / エフェクター / 構造解析 / 抵抗性タンパク質 / ユビキチン / シャペロン / 生理学

Research Abstract

We determined crystal structure of the chaperone complex important for plant immunity. The structure of an effector from potato blight disease was also determined. Various screenings, such as reverse genetics and functional assays, revealed that U-box type E3 ubiquitin ligases and autophagy related proteins are negative regulators for plant immunity.

Research Products

• [Journal Article] Shotguns in the front line : Phosphoproteomics in plants (2012)
  • Author(s): Nakagami, H., Sugiyama, N., Ishihama, Y., and Shirasu, K.
  • Journal Title: Plant Cell Physiol Volume: 53 Pages: 118-124
  • NAID: 10030307420
  • Peer Reviewed
• [Journal Article] Sequence divergent RXLR effectors share a structural fold conserved across plant pathogenic oomycete species (2012)
  • Author(s): Win, J., Krasileva, K. V., Kamoun, S., Shirasu, K. Staskawicz, B. J., Banfield, M. J.
  • Journal Title: PLoS Pathogens Volume: 8
  • Peer Reviewed
• [Journal Article] The HSP90 complex of plants (2012)
  • Author(s): Kadota, Y. and Shirasu, K.
  • Journal Title: Biochimica et Biophysica Acta(BBA)-Molecular Cell Research Volume: 1823 Pages: 689-697
  • Peer Reviewed
• [Journal Article] The main auxin biosynthesis pathway in Arabidopsis (2012)
  • Author(s): Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, H., Yaeno, T., Shirasu, K. Yao, H. McSteen, P., Zhao, Y., Hayashi, K., Kamiya, Y., Kasahara, H.
  • Journal Title: Proc. Natl. Acad. Sci. USA
  • Peer Reviewed
• [Journal Article] Phosphoproteomics in plants (2012)
  • Author(s): Nakagami, H., Sugiyama, N., Ishihama, Y., Shirasu, K.
  • Journal Title: Plant Cell Physiol Volume: 53 Issue: 1 Pages: 118-124
  • DOI: 10.1093/pcp/pcr148
  • Peer Reviewed
• [Journal Article] Sequence divergent RXLR effectors share a structural fold conserved across plant pathogenic oomycete species (2012)
  • Author(s): Win, J., Krasileva, K.V., Kamoun, S., Shirasu, K., Staskawicz, B.J., Banfield, M.J.
  • Journal Title: PLoS Pathogens Volume: 8 Issue: 1 Pages: e1002400-e1002400
  • DOI: 10.1371/journal.ppat.1002400
  • Peer Reviewed
• [Journal Article] The HSP90 complex of plants (2012)
  • Author(s): Kadota, Y., Shirasu, K.
  • Journal Title: Biochimica et Biophysica Acta (BBA)-Molecular Cell Research Volume: 1823 Issue: 3 Pages: 689-697
  • DOI: 10.1016/j.bbamcr.2011.09.016
  • Peer Reviewed
• [Journal Article] Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity (2011)
  • Author(s): Yaeno, T., Li, H., Chaparro-Garcia, A., Schornack, S., Koshiba, S., Watanabe, S., Kigawa, T., Kamoun, S., and Shirasu, K.
  • Journal Title: Proc. Natl. Acad. Sci. USA. Volume: 108 Pages: 14682-14687
  • Peer Reviewed
• [Journal Article] Agrobacterium rhizogenes-mediated transformation of the parasitic plant Phtheirospermum japonicum (2011)
  • Author(s): Ishida, J. K., Yoshida, S., Ito, M., Namba, S. and Shirasu, K.
  • Journal Title: PLoS One Volume: 6
  • Peer Reviewed
• [Journal Article] Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity (2011)
  • Author(s): Yaeno, T., Li, H., Chaparro-Garcia, A., Schornack, S., Koshiba, S., Watanabe, S., Kigawa, T., Kamoun, S., Shirasu, K.
  • Journal Title: Proc.Natl.Acad.Sci.USA. Volume: 108 Issue: 35 Pages: 14682-14687
  • DOI: 10.1073/pnas.1106002108
  • Peer Reviewed
• [Journal Article] Agrobacterium rhizogenes-mediated transformation of the parasitic plant Phtheirospermum japonicum (2011)
  • Author(s): Ishida, J.K., Yoshida, S., Ito, M., Namba, S., Shirasu, K.
  • Journal Title: PLoS One Volume: 6 Issue: 10 Pages: e25802-e25802
  • DOI: 10.1371/journal.pone.0025802
  • Peer Reviewed
• [Journal Article] The main auxin biosynthesis pathway in Arabidopsis (2011)
  • Author(s): Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, H., Yaeno, T., Shirasu, K., Yao, H., Mc Steen, P., Zhao, Y., Hayashi, K., Kamiya, Y., Kasahara, H.
  • Journal Title: Proc.Natl.Acad.Sci.USA. Volume: 108 Issue: 45 Pages: 18512-18517
  • DOI: 10.1073/pnas.1108434108
  • Peer Reviewed
• [Journal Article] 病原体による免疫制御化と植物の免疫戦略 (2011)
  • Author(s): 八丈野孝, 白須賢
  • Journal Title: 細胞工学 Volume: 30 Pages: 155-160
• [Journal Article] 動植物共通の免疫センサーの制御に働くタンパク質複合体-立体構造解析から機能に迫る (2011)
  • Author(s): 門田康弘, 白須賢
  • Journal Title: 生物と化学 Volume: 49 Pages: 154-155
  • NAID: 10027898577
• [Journal Article] Structural Basis for Assembly of Hsp90-Sgt1-CHORD Protein Complexes : Implications for Chaperoning of NLR Innate Immunity Receptors (2010)
  • Author(s): Zhang M., Kadota Y., Prodromou C., Shirasu K., and Pearl L. H.
  • Journal Title: Molecular Cell Volume: 39 Pages: 269-281
  • Peer Reviewed
• [Journal Article] Horizontal Gene Transfer by the Parasitic Plant Striga hermonthica (2010)
  • Author(s): Yoshida S., Maruyama S., Nozaki H., and Shirasu K.
  • Journal Title: Science Volume: 328 Pages: 1128-1128
  • Peer Reviewed
• [Journal Article] A full-length enriched cDNA library and expressed sequence tag analysis of the parasitic weed, Striga hermonthica (2010)
  • Author(s): Yoshida S., Ishida K J., Kamal M N., Ali M A, Namba S. and Shirasu K.
  • Journal Title: BMC Plant Biology Volume: 10 Pages: 55-55
  • Peer Reviewed
• [Journal Article] Large-scale comparative phosphoproteomics identifies conserved phosphorylation sites in plants (2010)
  • Author(s): Nakagami H., Sugiyama N., Mochida K., Daudi A., Yoshida Y., Toyoda T., Tomita M., Ishihama Y. and Shirasu K.
  • Journal Title: Plant Physiol Volume: 153 Pages: 1161-1174
  • Peer Reviewed
• [Journal Article] Ubiquitination in plant immunity (2010)
  • Author(s): Trujillo M. and Shirasu K.
  • Journal Title: Curr. Opin. in Plant Biol. Volume: 13 Pages: 402-408
  • Peer Reviewed
• [Journal Article] NLR sensors meet at the SGT1HSP90 crossroad (2010)
  • Author(s): Kadota Y., Shirasu K. and Guerois R.
  • Journal Title: Trends in Biochem. Sci Volume: 35 Pages: 199-206
  • Peer Reviewed
• [Journal Article] 12-Oxo-phytodienoic acid-Glutathione Conjugate is Transported into the Vacuole in Arabidopsis (2010)
  • Author(s): Ohkama-Ohtsu, N., Sasaki-Sekimoto, Y., Oikawa, A., Jikumaru, Y., Shinoda, S., Inoue, E., Kamide, Y., Yokoyama, T., Hirai, Y., Shirasu, K., Kamiya, Y., Oliver, D.J., Saito, K.
  • Journal Title: Plant Cell Physiol Volume: 52 Pages: 205-209
  • NAID: 10029708354
  • Peer Reviewed
• [Journal Article] Horizontal Gene Transfer by the Parasitic Plant Striga hermonthica (2010)
  • Author(s): Yoshida S., Maruyama S., Nozaki H., Shirasu K
  • Journal Title: Science Volume: 328 Pages: 1128-1128
  • Peer Reviewed
• [Journal Article] A full-length enriched cDNA library and expressed sequence tag analysis of the parasitic weed, Striga hermonthica (2010)
  • Author(s): Yoshida S., Ishida J.K., Kamal N.M., Ali A.M., Namba S., Shirasu K.
  • Journal Title: BMC Plant Biol Volume: 10
  • Peer Reviewed
• [Journal Article] Ubiquitination in plant immunity (2010)
  • Author(s): Trujillo M., Shirasu K.
  • Journal Title: Curr.Opin.in Plant Biol. Volume: 13 Pages: 402-408
  • Peer Reviewed
• [Journal Article] NLR sensors meet at the SGT1HSP90 crossroad (2010)
  • Author(s): Kadota Y., Shirasu K., Guerois R.
  • Journal Title: Trends in Biochem.Sci. Volume: 35 Pages: 199-207
  • Peer Reviewed
• [Journal Article] RanGAP2 Mediates Nucleocytoplasmic Partitioning of the NB-LRR Immune Receptor Rx in the Solanaceae, Thereby Dictating Rx Function (2010)
  • Author(s): Tameling, W.I.L., Nooijena, C., Ludwig, N., Boter, M, Slootweg, E., Goverse, A., Shirasu. K., Joosten, M.H.A.J.
  • Journal Title: Plant Cell Volume: 22 Pages: 4176-4194
  • Peer Reviewed
• [Journal Article] The Rab GTPase RabG3b functions in autophagy and contributes to tracheary element differentiation in Arabidopsis (2010)
  • Author(s): Kwon S.I., Cho H.J., Jung J.H., Yoshimoto K., Shirasu K., Park O.K.
  • Journal Title: Plant J. Volume: 64 Pages: 151-164
  • Peer Reviewed
• [Journal Article] Horizontal gene transfer by the parasitic plant Striga hermonthica (2010)
  • Author(s): Yoshida, S., Maruyama, S., Nozaki, H., Shirasu, K.
  • Journal Title: Science (in press)
  • Peer Reviewed
• [Journal Article] Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response in Arabidopsis (2009)
  • Author(s): Yoshimoto K., Jikumaru Y., Kamiya Y., Kusano M., Consonni C., Panstruga R., Ohsumi Y. and Shirasu K.
  • Journal Title: Plant Cell Volume: 60 Pages: 218-226
  • Peer Reviewed
• [Journal Article] RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens (2009)
  • Author(s): Narusaka M., Shirasu K., Noutoshi Y., Kubo Y., Shiraishi T., Iwabuchi M. and Narusaka Y.
  • Journal Title: Plant J Volume: 60 Pages: 218-226
  • NAID: 130006991284
  • Peer Reviewed
• [Journal Article] Multiple layers of incompatibility to the parasitic witchweed, Striga hermonthica (2009)
  • Author(s): Yoshida, S. and Shirasu, K.
  • Journal Title: New Phytologist Volume: 183(1) Pages: 180-189
  • Peer Reviewed
• [Journal Article] The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors (2009)
  • Author(s): Shirasu, K.
  • Journal Title: Annual Review of Plant Biology Volume: 60 Pages: 139-164
  • Peer Reviewed
• [Journal Article] Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response in Arabidopsis (2009)
  • Author(s): Yoshimoto K., Jikumaru Y., Kamiya Y., Kusano M., Consonni C., Panstruga R., Ohsumi Y., Shirasu K.
  • Journal Title: Plant Cell 60 Pages: 218-226
  • Peer Reviewed
• [Journal Article] The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors (2009)
  • Author(s): Shirasu, K.
  • Journal Title: Annual Review of Plant Biology 60 Pages: 139-164
  • Peer Reviewed
• [Journal Article] The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors (2009)
  • Author(s): Shirasu, K.
  • Journal Title: Annual Review of Plant Biology 60(印刷中)
  • Peer Reviewed
• [Journal Article] Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants. (2008)
  • Author(s): Kadota, Y., Amigues, B., Ducassou, L., Madaoui, H., Ochsenbein, F., Guerois, R. and Shirasu, K.
  • Journal Title: EMBO reports Volume: 9 Pages: 1209-1215
  • Peer Reviewed
• [Journal Article] Structural and functional coupling of Hsp90-and Sgt1-centred multi-protein complexes (2008)
  • Author(s): Zhang, M., Boter, M., Li, K., Kadota, Y., Panaretou, B., Prodromou, C., Shirasu, K. and Pearl, L.
  • Journal Title: EMBO J Volume: 27 Pages: 2789-2798
  • Peer Reviewed
• [Journal Article] Negative regulation of PAMP-triggered immunity by E3 ubiquitin ligase triplet in Arabidopsis (2008)
  • Author(s): Trujillo, M., Ichimura, K., Casais, C. and Shirasu, K.
  • Journal Title: Current Biology Volume: 18 Pages: 1396-1401
  • Peer Reviewed
• [Journal Article] Inhibition of shoot branching by new terpenoid plant hormones (2008)
  • Author(s): Umehara, M., Hanada, A., Yoshida, S., Akiyama, K., Arite, T., Takeda-Kamiya, N., Magome, H., Kamiya, Y., Shirasu, K., Yoneyama, K., Kyozuka, J. and Yamaguchi, S.
  • Journal Title: Nature Volume: 455 Pages: 195-200
  • Peer Reviewed
• [Journal Article] Large-scale phosphorylation mapping reveales the extent of tyrosine phosphorylation in Arabidopsis (2008)
  • Author(s): Sugiyama, N., Nakagami, H., Mochida, K., Daudi, A., Tomita, M., Shirasu, K. and Ishihama, Y.
  • Journal Title: Molecular Systems Biology Volume: 4 Pages: 493-493
  • Peer Reviewed
• [Journal Article] Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants (2008)
  • Author(s): Kadota, Y., Amigues, B., Ducassou, L., Madaoui, H., Ochsenbein, F., Guerois, R., Shirasu, K.
  • Journal Title: EMBO reports 9 Pages: 1209-1215
  • Peer Reviewed
• [Journal Article] Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes (2008)
  • Author(s): Zhang, M., Boter, M., Li, K., Kadota, Y., Panaretou, B., Prodromou, C., Shirasu, K., Pearl, L.
  • Journal Title: EMBO J. 27 Pages: 2789-2798
  • Peer Reviewed
• [Journal Article] Negative regulation of PAMP-triggered immunity by E3 ubiquitin ligase triplet in Arabidopsis (2008)
  • Author(s): Trujillo, M., Ichimura, K., Casais, C., Shirasu, K.
  • Journal Title: Current Biology 18 Pages: 1396-1401
  • Peer Reviewed
• [Journal Article] Structural and functional coupling of Hsp90-and Sgt1-centred multi-protein complexes (2008)
  • Author(s): Zhang, M., Boter, M., Li, K., Kadota, Y., Panaretou, B., Prodromou, C., Shirasu, K., Pearl, L
  • Journal Title: EMBO J 27 Pages: 2789-2798
  • Peer Reviewed
• [Journal Article] Inhibition of shoot branching by new terpenoid plant hormones (2008)
  • Author(s): Umehara, M., Hanada, A., Yoshida, S., Akiyama, K., Arite, T., Takeda-Kamiya, N., Magome, H., Kamiya, Y., Shirasu, K., Yoneyama, K., Kyozuka, J., Yamaguchi, S.
  • Journal Title: Nature 455 Pages: 195-200
  • Peer Reviewed
• [Journal Article] RACK1 functions in rice innate immunity by interacting with the Rac1 immune complex (2008)
  • Author(s): Nakashima, A., Chen, L., Thao, N. P., Fujiwara, M., Wong, H. L., Kuwano, M., Umeura, K., Shirasu, K., Kawasaki, T, Shimamoto K.
  • Journal Title: Plant Cell 20 Pages: 2265-2279
  • Peer Reviewed
• [Journal Article] Large-scale phosphorylation mapping reveales the extent of tyrosine phosphorylation in Arabidopsis (2008)
  • Author(s): Sugiyama, N., Nakagami, H., Mochida, K., Daudi, A., Tomita, M., Shirasu, K., Ishihama, Y.
  • Journal Title: Molecular Systems Biology 4 Pages: 193-193
  • Peer Reviewed
• [Presentation] ハマウツボ科寄生植物のトランスクリプトーム解析 (2012)
  • Author(s): 吉田聡子, Ishida Juliane, Wafula Eric, dePamphilis Claude,白須賢
  • Organizer: 第53回日本植物生理学会年会
  • Place of Presentation: 京都市日本
  • Year and Date: 2012-03-16
• [Presentation] ジャガイモ疫病菌が分泌するRXLRエフェクターAVR3aの病原性機能にはホスファチジルイノシトールリン酸との結合が必要である (2012)
  • Author(s): 八丈野孝,李華, Chaparro-Garcia Angela, Schornack Sebastian,小柴生造,渡部暁,木川隆則, Kamoun Sophien,白須賢
  • Organizer: 第53回日本植物生理学会年会
  • Place of Presentation: 京都市日本
  • Year and Date: 2012-03-16
• [Presentation] Genomic-scale analysis of the parasitic plants-Towards understanding of the plant parasitism (2012)
  • Author(s): 白須賢
  • Organizer: Japan-Australia Symposium on Plant Sciences for Agriculture
  • Place of Presentation: 北海道大学(北海道)(招待講演)
  • Year and Date: 2012-01-19
• [Presentation] ジャガイモ疫病菌が分泌するRXLRエフェクターAVR3aの病原性機能にはホスファチジルイノシトールリン酸との結合が必要である (2012)
  • Author(s): 八丈野孝, 李華, Angela Chaparro-Garcia, Sebastian Schornack, 小柴生造, 渡部暁, 木川隆則, Sophien Kamoun, 白須賢
  • Organizer: 第53回日本植物生理学会年会
  • Place of Presentation: 京都産業大学(京都府)
• [Presentation] ジャガイモ疫病菌が分泌するエフェクターAVR3aの病原性機能には脂質との結合が必要である (2012)
  • Author(s): 八丈野孝, 李華, Angela Chaparro-Garcia, Sebastian Schornack, 小柴生造, 渡部暁, 木川隆則, Sophien Kamoun, 白須賢
  • Organizer: 平成24年日本植物病理学会大会
  • Place of Presentation: 福岡国際会議場(福岡県)
• [Presentation] Genomic-scale analysis of the parasitic plants-Towards understanding of the plant parasitism (2011)
  • Author(s): 白須賢
  • Organizer: Plant Genomes & Biotechnology : From Genes to Networks
  • Place of Presentation: Cold Spring Harbor Laboratory New York, USA)(招待講演)
  • Year and Date: 2011-12-02
• [Presentation] Genomic-scale analysis of the parastic plants-Towards understanding of the plant parasitism Plant Genomes & Biotechnology (2011)
  • Author(s): Yoshida. S, Ishida. J, Shirasu. K.
  • Organizer: From Genes To Networks
  • Place of Presentation: New York USA
  • Year and Date: 2011-12-01
• [Presentation] 植物免疫関連タンパク質の構造機能解析 (2011)
  • Author(s): 白須賢
  • Organizer: 第84回日本生化学会大会
  • Place of Presentation: 京都日本
  • Year and Date: 2011-09-23
• [Presentation] 植物免疫関連タンパク質の構造機能解析 (2011)
  • Author(s): 白須賢
  • Organizer: 第84回日本生化学会大会
  • Place of Presentation: 京都国際会館(京都府)(招待講演)
  • Year and Date: 2011-09-23
• [Presentation] ジャガイモ疫病菌が分泌するRXLRエフェクターAVR3aの構造機能解析 (2011)
  • Author(s): 八丈野孝
  • Organizer: 日本植物病理学会関東部会若手の会
  • Place of Presentation: イーアスつくば(茨城県)(招待講演)
  • Year and Date: 2011-09-16
• [Presentation] ジャガイモ疫病菌エフェクターAVR3aの構造機能解析 (2011)
  • Author(s): 八丈野孝, 門田康弘, 瀧澤香, 李華, 大沢登, 半田徳子, 寺田貴帆, 小柴生造, 白水美香子, 渡部暁, 木川隆則, 横山茂之, Sophien Kamoun, 白須賢
  • Organizer: 平成23年日本植物病理学会大会
  • Place of Presentation: 東京農工大学(東京都)
  • Year and Date: 2011-03-28
• [Presentation] ジャガイモ疫病菌エフェクターAVR3aの構造機能解析 (2011)
  • Author(s): 八丈野孝, 門田康弘, 瀧澤香, 李華, 大沢登, 半田徳子, 寺田貴帆, 小柴生造, 白水美香子, 渡部暁, 木川隆則, 横山茂之, Sophien Kamoun, 白須賢
  • Organizer: 第52回日本植物生理学会年会
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2011-03-20
• [Presentation] Towards understanding the parasitisum of Striga Hermonthica (2011)
  • Author(s): Shirasu. K.
  • Organizer: 2011 International Plant Pathogenomics Conference
  • Place of Presentation: Shenzhen China
  • Year and Date: 2011-01-25
• [Presentation] Structure-based functional analysis of plant immunity-related proteins (2010)
  • Author(s): 白須賢
  • Organizer: 1^<st> Asian Conference on Plant-Microbe Symbiosis and Nitrogen Fixstion
  • Place of Presentation: 青島パームビーチホテル,(宮崎県)(招待講演)
  • Year and Date: 2010-09-20
• [Presentation] A large scale molecular analysis of the parastic plant Striga hermothica (2010)
  • Author(s): Shirasu. K.
  • Organizer: International Symposium on Biodiversity Sciences(ISBDS2010)
  • Place of Presentation: Nagoya Japan
  • Year and Date: 2010-08-02
• [Presentation] 植物免疫におけるU-BOXタンパク質の役割 (2010)
  • Author(s): 白須賢
  • Organizer: 第10回日本蛋白質科学会年会
  • Place of Presentation: 札幌コンベンションセンター(北海道)(招待講演)
  • Year and Date: 2010-06-17
• [Presentation] Plant autophagy negatively regulates cell death by controlling salicylic acid signaling during senescence and the innate immune response (2010)
  • Author(s): Yoshimoto. K, Osumi. Y, Shirasu. K.
  • Organizer: 21st International Conference on Arabidopsis Research(ICAR 2010)
  • Place of Presentation: Yokohama Japan
  • Year and Date: 2010-06-07
• [Presentation] オートファジー能欠損シロイヌナズナにおけるプログラム細胞死促進の原因は過剰なサリチル酸シグナリングである (2010)
  • Author(s): 吉本光希,大隅良典,白須賢
  • Organizer: 平成22年度日本植物病理学会大会
  • Place of Presentation: 京都日本
  • Year and Date: 2010-04-20
• [Presentation] Towards understanding the parasitism of Striga hermonthica (2010)
  • Author(s): 白須賢
  • Organizer: Crop Functional Genomics 2010
  • Place of Presentation: Jeju, Korea(招待講演)
  • Year and Date: 2010-04-16
• [Presentation] Towards understanding the parasitism of Striga hermonthica Crop (2010)
  • Author(s): Shirasu. K
  • Organizer: Functional Genomics 2010
  • Place of Presentation: Jeju Korea
  • Year and Date: 2010-04-15
• [Presentation] Unravelling plant immunity signalling pathways with small molecules. Keystone Symposia (2010)
  • Author(s): Saska. I, Noutoshi. Y, Shirasu. K.
  • Organizer: Receptors and Signaling in Plant Development and Biotic Interactions
  • Place of Presentation: Tahoe City USA
• [Presentation] 修飾されたタンパク質の解析技術(リン酸化) (2009)
  • Author(s): 白須賢
  • Organizer: 第142回農林交流センターワークショップ
  • Place of Presentation: つくば日本
  • Year and Date: 2009-11-19
• [Presentation] Structural and functional analysis of the SGT1-RAR1-HSP90 complex required for plant immunity (2009)
  • Author(s): Kadota. Y, Zhang. M, Guerois. R, Prodromou. C, Pearl. L, Shirasu. K.
  • Organizer: IS-MPMI 2009 XIV International Congress Quebec City
  • Place of Presentation: Canada
  • Year and Date: 2009-07-21
• [Presentation] ハイスループット無細胞タンパク質発現系を用いた病害抵抗性関連タンパク質の立体構造解析 (2009)
  • Author(s): 八丈野孝, 門田康弘, 五島美絵, 大沢登, 半田徳子, 寺田貴帆, 白水美香子, 横山茂之, 白須賢
  • Organizer: 第50回日本植物病理学会年会
  • Place of Presentation: 山形大学
  • Year and Date: 2009-03-27
• [Presentation] ポストゲノム的手法による植物免疫分子機構の解析 (2009)
  • Author(s): 白須賢
  • Organizer: 第50回日本植物病理学会年会
  • Place of Presentation: 山形大学
  • Year and Date: 2009-03-27
• [Presentation] 抵抗性蛋白質の安定化に必須なSGT1-HSP90複合体の立体構造及び機能解析 (2009)
  • Author(s): 門田康弘, Marta Boter, Minghao Zhang, Beatrice Amigues, Chrisostomos Prodromou, Laurence H. Pearl, Raphael Guerois, 白須賢
  • Organizer: 第50回日本植物病理学会年会
  • Place of Presentation: 山形大学
  • Year and Date: 2009-03-27
• [Presentation] ハイスループット無細胞発現系を用いた病害抵抗性関連タンパク質の立体構造解析 (2009)
  • Author(s): 八丈野孝, 門田康弘, 五島美絵, 大沢登, 半田徳子, 寺田貴帆, 白水美香子, 横山茂之, 白須賢
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2009-03-24
• [Presentation] 動植物共通の免疫レセプターの安定化に必須なSGT1-HSP90複合体の立体構造及び機能解析 (2009)
  • Author(s): 門田康弘, Boter Marta, Zhang Minghao, Amigues Beatrice, Prodromou Chrisostomos, Pearl Laurence, Guerois Raphael,白須賢
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋日本
  • Year and Date: 2009-03-21
• [Presentation] ハイスループット無細胞タンパク質発現系を用いた病害抵抗性関連タンパク質の立体構造解析 (2009)
  • Author(s): 八丈野孝,門田康弘,五島美絵,大沢登,半田徳子,白水美香子,横山茂之,白須賢
  • Organizer: 平成21年度日本植物病理学会大会
  • Place of Presentation: 山形日本
• [Presentation] ケミカルバイオロジーによるシロイヌナズナ過敏感細胞死制御機構の解明 (2009)
  • Author(s): 能年義輝,白須賢
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋日本
• [Presentation] ハイスループット無細胞発現系を用いた病害抵抗性関連タンパク質の立体構造解析 (2009)
  • Author(s): 八丈野孝,門田康弘,五島美絵,大沢登,半田徳子,白水美香子,横山茂之,白須賢
  • Organizer: 第50回日本植物生理学会年会
  • Place of Presentation: 名古屋日本
• [Presentation] The SGT1-HSP90 chaperone complex for NLR-protein dependent innate immunity (2008)
  • Author(s): 白須賢
  • Organizer: Argentine Society for Research in Biochemistry and Molecular Biology (SAIB)
  • Place of Presentation: Portal del Lago Hotel, Cordoba, Argentina
  • Year and Date: 2008-11-10
• [Presentation] Structural and functional analysis of the SGT1-HSP90 chaperone complex required for NLR-protein dependent innate immunity (2008)
  • Author(s): 白須賢
  • Organizer: 4^<th> International Conference 'Hsp90 Chaperone Machinery'
  • Place of Presentation: The monastery, Seeon, Germany
  • Year and Date: 2008-11-04
• [Presentation] Structure and Function of the N-terminal Domain of Hsp90 in Complex with the CS-domain of Sgt1 (2008)
  • Author(s): Zhang. M, Boter. M, Li. K, Kadota. Y, Panaretou. B, Prodromou. C, Shirasu. K, Pearl. L.
  • Organizer: 4th International Conference on The Hsp90 Chaperone Machine Bavaria Germany
  • Year and Date: 2008-10-03
• [Presentation] Plant autophagy negatively regulates senescence by eliminating salicylic acid signaling (2008)
  • Author(s): Yoshimoto. K, Ohsumi. Y, Shirasu. K
  • Organizer: Gordon Research Conferences on Plant Senescence South Hadley USA
• [Presentation] Structural and functional analysis of RAR1-SGT1-HSP90 complex (2008)
  • Author(s): Kadota. Y, Boter. M, Zhang. M, Amigues. B, Prodromou. C, Pearl. L, Guerois. R, Shirasu. K
  • Organizer: Keystone Symposia on Molecular and Cellular Biology Keystone USA
• [Presentation] Structure and Function of the N-terminal Domain of Hsp90 in Complex with the CS-domain of Sgt1 (2008)
  • Author(s): Zhang. M, Boter. M, Li. K, Kadota. Y, Panaretou. B, Prodromou. C, Shirasu. K, Pearl. L
  • Organizer: 4th International Conference on The Hsp90 Chaperone Machine
  • Place of Presentation: Bavaria Germany
• [Presentation] Structural and functional analysis of the SGT1-HSP90 chaperone complex required for NLR-protein dependent innate immunity (2008)
  • Author(s): Kadota. Y, Amigues. B, Guerois. R, Shirasu. K
  • Organizer: 4th International Conference on The Hsp90 Chaperone Machine
  • Place of Presentation: Bavaria Germany
• [Presentation] Plant autophagy negatively regulates senescence by eliminating salicylic acid signaling (2008)
  • Author(s): Yoshimoto. K, Ohsumi. Y, Shirasu. K
  • Organizer: Gordon Research Conferences on Plant Senescence
  • Place of Presentation: South Hadley USA
• [Presentation] Structural and functional analysis of RAR1-SGT1-HSP90 complex (2008)
  • Author(s): 門田 康弘, 白須 賢
  • Organizer: Keystone Symposia"Plant Innate Immunity"
  • Place of Presentation: Keystone Resort,USA
• [Book] "相互認識遺伝子とその産物"植物病理学 (2010)
  • Author(s): 白須賢
  • Publisher: 文永堂出版
• [Book] Plant Mitogen-Activated Protein Kinase Cascades in Signaling Crosstalk, In "Signal Crosstalk in Plant Stress Responses" (2009)
  • Author(s): Takahashi, F., Ichimura, K., Shinozaki, K., and Shirasu, K
• [Book] "植物免疫,防御"植物の百科事典 (2009)
  • Author(s): 白須賢
  • Publisher: 朝倉書店
• [Book] Plant Mitogen-Activated Protein Kinase Cascades in Signaling Crosstalk, In "Signal Crosstalk in Plant Stress Responses"(Keiko Yoshioka and Kazuo Shinozaki eds) (2009)
  • Author(s): Takahashi, F., Ichimura, K., Shinozaki, K., Shirasu, K.
  • Publisher: Wiley-Blackwell
• [Remarks] Plant Cell(2009)について:科学新聞(2009.10.16)、日経産業新聞(2009.9.25)新聞報道
• [Remarks] Molecular Cell(2009)について:科学新聞(2010.8.6)、日刊工業新聞(2010.7.30)新聞報道
• [Remarks] Plant Physiol.(2010)について:日経産業新聞(2010.7.29)、化学工業日報(2010.7.12)新聞報道
• [Remarks] Science(2010)について:日経産業新聞(2010.6.3)、化学工業日報(2010.5.28)新聞報道
• [Remarks]
  • URL: http://ksg.psc.riken.jp/
• [Remarks]
  • URL: http://ksg.psc.riken.jp/index.en.html
• [Remarks] ホームページ
  • URL: http://ksg.psc.riken.jp/index.ja.html
• [Remarks]
  • URL: http://twitter.com/ShirasuLab
• [Remarks]
  • URL: http://ksg.psc.riken.jp/Projects_J.html
• [Patent(Industrial Property Rights)] 複数の病害に対して抵抗性を示す植物及びその作出法 (2009)
  • Inventor(s): 鳴坂義弘、鳴坂真理、白須賢
  • Industrial Property Rights Holder: 岡山県、(独)理化学研究所
  • Filing Date: 2009-07-29
  • Overseas
• [Patent(Industrial Property Rights)] 植物病害抵抗性誘導剤 (2009)
  • Inventor(s): 能年義輝、白須賢
  • Industrial Property Rights Holder: (独)理化学研究所
  • Filing Date: 2009-03-27
  • Overseas
• [Patent(Industrial Property Rights)] 複数の病害に対して抵抗性を示す植物及びその作出法 (2009)
  • Inventor(s): 鳴坂義弘, 鳴坂真理, 白須賢
  • Industrial Property Rights Holder: 岡山県、(独) 理化学研究所
  • Filing Date: 2009-07-29
  • Overseas
• [Patent(Industrial Property Rights)] 植物病害抵抗性誘導剤 (2009)
  • Inventor(s): 能年義輝, 白須賢
  • Industrial Property Rights Holder: (独) 理化学研究所
  • Filing Date: 2009-03-27
  • Overseas
• [Patent(Industrial Property Rights)] 複数の病害に対して抵抗性を示す植物及びその作出法 (2008)
  • Inventor(s): 鳴坂義弘、鳴坂真理、白須賢
  • Industrial Property Rights Holder: 岡山県、(独)理化学研究所
  • Filing Date: 2008-07-31
• [Patent(Industrial Property Rights)] 植物病害抵抗性誘導剤 (2008)
  • Inventor(s): 能年義輝、白須賢
  • Industrial Property Rights Holder: (独)理化学研究所
  • Filing Date: 2008-03-28
• [Patent(Industrial Property Rights)] 複数の病害に対して抵抗性を示す植物及びその作出法 (2008)
  • Inventor(s): 鳴坂義弘, 鳴坂真理, 白須賢
  • Industrial Property Rights Holder: 岡山県、(独) 理化学研究所
  • Filing Date: 2008-07-31
• [Patent(Industrial Property Rights)] 植物病害抵抗性誘導剤 (2008)
  • Inventor(s): 能年義輝, 白須賢
  • Industrial Property Rights Holder: (独) 理化学研究所
  • Filing Date: 2008-03-28