| Budget Amount *help |
¥25,480,000 (Direct Cost: ¥19,600,000、Indirect Cost: ¥5,880,000)
Fiscal Year 2009: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2008: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2007: ¥11,960,000 (Direct Cost: ¥9,200,000、Indirect Cost: ¥2,760,000)
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| Research Abstract |
To realize the targeting therapy against intractable tumors such as pancreatic tumors and molecular cancer therapy using nucleic acids, we developed novel nanocarriers based on polymeric micelles, which can avoid biological barriers at the tissue and organelle levels and function responding to environmental changes or physical stimuli, by engineering functional polymeric materials. The usefulness of such nanocarriers has been demonstrated by in vitro and in vivo experiments.
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