| Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2008: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2007: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
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| Research Abstract |
Silicone elastomer or polyethylene substrates were irradiated under various conditions by the simultaneous use of oxygen cluster and monomer (O_2CM) ion beams, and then soaking in CaCl_2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF).The hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O_2CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer or polyethylene substrates.
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