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Control of nonlinear processes of protein solution and biological cells induced by focused femtosecond laser

Research Project

Project/Area Number 19686007
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Applied optics/Quantum optical engineering
Research InstitutionNara Institute of Science and Technology (2008-2010)
Hamano Life Science Research Foundation (2007)

Principal Investigator

HOSOKAWA Youchiroh (HOSOKAWA Yoichiroh)  Nara Institute of Science and Technology, 物質創成科学研究科, 特任准教授 (20448088)

Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2008: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2007: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Keywordsフェムト秒レーザー / 原子間力顕微鏡 / 蛋白質 / 細胞 / 衝撃波
Research Abstract

When an intense infrared-femtosecond-laser is focused into biological materials, shockwave and cavitation bubble are generated at the laser focal point, in which an explosive morphological change of water is induced by an effective multiphoton absorption. I developed a new local force measurement system to estimate the impulsive force due to the shockwave and cavitation bubble generated in biological materials and elucidated time and spatial evolution of these phenomena. On the basis of this knowledge, new control and measurement methods of single cell or intracellular protein were devised.

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (172 results)

All 2011 2010 2009 2008 2007 Other

All Journal Article (40 results) (of which Peer Reviewed: 35 results) Presentation (117 results) Book (8 results) Remarks (5 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Non-contact etimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy.2011

    • Author(s)
      Y.Hosokawa, M.Hagiyama, T.Iino, Y.Murakami, A.Ito.
    • Journal Title

      Proc.Natl.Acad.Sci. Vol.108

      Pages: 1777-1782

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Induction of the cell-cell connections by using in-situ laser lithography on a perfluoroalkyl-layered cultivation platform.2011

    • Author(s)
      K.Okano, D.Yu, A.Matsui, Y.Maezawa, Y.Hosokawa, A.Kira, M.Matsubara, I.Liau, H.Tsubokawa, H.Masuhara.
    • Journal Title

      Chem Bio Chem Vol.12

      Pages: 795-801

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Morphological evaluation of cell differentiation after the isolation of single cells by a femtosecond laser-induced impulsive force.2011

    • Author(s)
      Y.Maezawa, K.Okano, M.Matsubara, H.Masuhara, Y.Hosokawa.
    • Journal Title

      Biomed.Microdevices Vol.13

      Pages: 117-122

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Morphological evaluation of cell differentiation after the isolation of single cells by a femtosecond laser-induced impulsive force2011

    • Author(s)
      Yasuyo Maezawa
    • Journal Title

      Biomedical Microdevices

      Volume: Vol.13 Pages: 117-122

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-contact estimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy2011

    • Author(s)
      Yoichiroh Hosokawa
    • Journal Title

      Proceedings of the National Academy of Sciences of USA

      Volume: Vol.108 Pages: 1777-1782

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Induction of the cell-cell connections by using in-situ laser lithography on a perfluoroalkyl-layered cultivation platform2011

    • Author(s)
      Kazunori Okano
    • Journal Title

      ChemBioChem

      Volume: Vol.12 Pages: 795-801

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct measurement of femtosecond laser impulse in water by atomic force microscopy2010

    • Author(s)
      T.Iino, Y.Hosokawa
    • Journal Title

      Appl.Phys.Express Vol.3

      Pages: 107002-107002

    • NAID

      10027441651

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] In situ observation of cell detachment process initiated by femtosecond laser-induced stress wave.2010

    • Author(s)
      Y.Maezawa, Y.Hosokawa, K.Okano, M.Matsubara, H.Masuhara.
    • Journal Title

      Appl.Phys.A. Vol.101

      Pages: 127-131

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Micro-channel fabrication by femtosecond laser to arrange neuronal cells on multi-electrode arrays2010

    • Author(s)
      C.Hosokawa, M.Suzuki, T.Taguchi, A.Kiyohara, Suguru. N.Kudoh, Y.Hosokawa, K.Okano, H.Masuhara.
    • Journal Title

      Appl.Phys.A Vol.101

      Pages: 423-428

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Micro-channel fabrication by femtosecond laser to arrange neuronal cells on multi-electrode arrays2010

    • Author(s)
      Chie Hosokawa
    • Journal Title

      Applied Physics A

      Volume: Vol.101 Pages: 423-428

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In situ observation of cell detachment process initiated by femtosecond laser-induced stress wave2010

    • Author(s)
      Yasuyo Maezawa
    • Journal Title

      Applied Physics A

      Volume: Vol.101 Pages: 127-131

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct measurement of femtosecond laser impulse in water by atomic force microscopy2010

    • Author(s)
      Takanori Iino
    • Journal Title

      Applied Physics Express

      Volume: Vol.3 Pages: 107002-107002

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Micropatterning of perfluoroalkyl self-assembled monolayer for arraying proteins and cells on a chip.2009

    • Author(s)
      A.Kira, K.Okano, Y.Hosokawa, A.Naito, K.Fuwa, J.Yuyama, H.Masuhara.
    • Journal Title

      Appl.Surf.Sci. Vol.255

      Pages: 7647-7651

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gene delivery process in a single animal cell after femtosecond laser microinjection.2009

    • Author(s)
      Y.Hosokawa, S.Iguchi, R.Yasukuni, Y.Hiraki, C.Shukunami, H.Masuhara.
    • Journal Title

      Appl.Surf.Sci. Vol.255

      Pages: 9880-9884

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gene Delivery Process in a Single Animal Cell after Femtosecond Laser Microinjection2009

    • Author(s)
      Y. Hosokawa, S. Iguchi, R. Yasukuni, Y. Hiraki, C. Shukunami, H. Masuhara
    • Journal Title

      Appl. Surf. Sci. Vol.255

      Pages: 9880-9884

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] In-situ arrangement of living cells on a fabricated surface by femtosecond laser2009

    • Author(s)
      K.Okano, Y.Maezawa, Y.Hosokawa, A.Kira, M.Mastubara, H.Masuhara
    • Journal Title

      Proceedings of Micro Total Analysis Systems 2009 : The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

      Pages: 1249-1251

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene Delivery Process in a Single Animal Cell after Femtosecond Laser Microinjection2009

    • Author(s)
      Yoichiroh Hosokawa, Seriya Iguchi, Ryohei Yasukuni, Yuji Hiraki, Chisa Shukunami, Hiroshi Masuhara
    • Journal Title

      Applied Surface Science Vol.255 (No.24)

      Pages: 9880-9884

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Micropatterning of perfluoroalkyl self-assembled monolayers for arraying proteins and cells on chips2009

    • Author(s)
      Atsushi Kira, Kazunori Okano, Yoichiroh Hosokawa, Akira Naito, Koh Fuwa, Jyunpei Yuyama, Hiroshi Masuhara
    • Journal Title

      Applied Surface Science Vol.255 (No.17)

      Pages: 7647-7651

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene Delivery Process in a Single Animal Cell after Fentoiecond Laser Microinjection2009

    • Author(s)
      Yoichiroh Hosokawa
    • Journal Title

      Applied Surface Science (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Femtosecond laser modification of living neuronal network.2008

    • Author(s)
      C.Hosokawa, S.N.Kudoh, A.Kiyohara, Y.Hosokawa, K.Okano, H.Masuhara, T.Taguchi.
    • Journal Title

      Appl.Phys.A. Vol.93

      Pages: 57-63

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nanoparticle injection to single animal cells using femtosecond laser-induced impulsive force2008

    • Author(s)
      A.Yamaguchi, Y.Hosokawa, G.Loit, T.Asahi, H.Masuhara.
    • Journal Title

      Appl.Phys.A. Vol.93

      Pages: 39-43

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Laser microfabrication and rotation of ship-in-a-bottle optical rotators.2008

    • Author(s)
      S.Matsuo, S.Kiyama, Y.Shichijo, T.Tomita, S.Hashimoto, Y.Hosokawa, H.Masuhara.
    • Journal Title

      Appl.Phys.Lett. Vol.93

      Pages: 51107-51107

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymalstem cells to chondrocytes.2008

    • Author(s)
      M.Takagi, T.Kitabayashi, S.Koizumi, H.Hirose, S.Kondo, M.Fujiwara, K.Ueno, M.Hiroaki, Y.Hosokawa, H.Masuhara, S.Wakitani.
    • Journal Title

      Biotechnol.Lett. Vol.30

      Pages: 1189-1195

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymal stem cells to chondrocytes.2008

    • Author(s)
      M.Takagi, T.Kitabayashi, S.Koizumi, H.Hirose, S.Kondo, M.Fujiwara, K.Ueno, M.Hiroaki, Y.Hosokawa, H.Masuhara, S.Wakitani.
    • Journal Title

      Biotechnol.Lett. Vol.30

      Pages: 1189-1195

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymalstem cells to chondrocytes2008

    • Author(s)
      M. Takagi, T. Kitabayashi, S. Koizumi, H. Hirose, S. Kondo, M. Fujiwara, K. Ueno, M. Hiroaki, Y. Hosokawa, H. Masuhara, S. Wakitani
    • Journal Title

      Biotechnol. Lett. Vol.30

      Pages: 1189-1195

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Nanoparticle injection to single animal cells using femtosecond laser-induced impulsive force2008

    • Author(s)
      A. Yamaguchi, Y. Hosokawa, G. Loit, T. Asahi, H. Masuhara
    • Journal Title

      Appl. Phys. A Vol.93

      Pages: 39-43

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymal stem cells to chondrocytes2008

    • Author(s)
      Mutsunii Takagi
    • Journal Title

      Biotec. Lett. Vol.30 No.7

      Pages: 1189-1195

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Laser microfabrication and rotation of ship-in-a-bottle optical rotators2008

    • Author(s)
      Shigeki Matsuo
    • Journal Title

      Appl. Phys. Lett. Vol.93 No.5

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nanoparticle injection to single animal cells using femtosecond laser-induced impulsive force2008

    • Author(s)
      Atsushi Yamaguchi
    • Journal Title

      Appl. Phys. A Vol.93, No.1

      Pages: 39-43

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Femtosecond laser modification of living neuronal network2008

    • Author(s)
      Chie Hosokawa
    • Journal Title

      Appl. Phys. A Vol.93 No.1

      Pages: 57-63

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Femtosecond Laser Manipulation Techniques for Individual Patterning of Biological Micro-object2008

    • Author(s)
      Yoichiroh Hosokawa, YuQiang Jiang, Isamu Oh, Noriko Takizawa, Takayuki Uwada, Kazunori Okano, Hiroshi Masuhara
    • Journal Title

      Proc.SPIE Vol.6854

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Viability evaluation of culture cells patterned by femtosecond laser-induced impulsive force2008

    • Author(s)
      Noriko Takizawa, Kazunori Okano, Takayuki Uwada, Yoichiroh Hosokawa, Hiroshi Masuhara
    • Journal Title

      Proc.SPIE Vol.6854

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Smart bombing a single targeted cell with felmtogram order reagents using laser-induced shockwave technique2008

    • Author(s)
      Kazunori Okano, Noriko Takizawa, Takayuki Uwada, Yoichiroh Hosokawa, Hiroshi Masuhara
    • Journal Title

      Proc.SPIE Vol.6854

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Organic molecular sensing by single metal porphyrin nanoparticles2008

    • Author(s)
      Takayuki Uwada, Yoichiroh Hosokawa, Noriko Takizawa, Kazuyoshi Okano, Hiroshi Masuhara
    • Journal Title

      Proc.SPIE Vol.6854

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Laser fabrication and crystallization of nano materials2008

    • Author(s)
      Teruki Sugiyama;Tsuyoshi Asahi;Kenichi Yuyama;Hiroki Takeuchi Hveon-Gu Jeon;Yoichiroh Hosokawa;Hiroshi Masuhara
    • Journal Title

      Proc.SPIE Vol.6891

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Correlation between cell morphology and aggrecan gene expression level during differentiation from mesenchymalstem cells to chondrocytes2008

    • Author(s)
      Mutsumi Takagi, Takayuki Kitabayashi, Satoru Koizumi, Haruka Hirose, Shin-ichi Kondo, Masashi Fujiwara, Kosei Ueno, Misawa Hiroaki, Yoichiroh Hosokawa, Hiroshi Masuhara, Shigeyuki Wakitani
    • Journal Title

      Biotechnol.Lett.

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single cell control based on femtosecond laser-induced nonlinear phenomena.2007

    • Author(s)
      Y.Hosokawa, R.Yasukuni, T.Kaji, A.Yamguchi, S.Iguchi, T.Asahi, H.Masuhara.
    • Journal Title

      The Rev.Laser Eng.(Japanese) Vol.35

      Pages: 430-435

    • NAID

      10019524725

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-destructive micro-patterning of living animal cells using focused femtosecond laser-induced impulsive force.2007

    • Author(s)
      T.Kaji, S.Ito, H.Miyasaka, Y.Hosokawa, H.Masuhara, C.Shukunami, Y.Hiraki.
    • Journal Title

      Appl.Phys.Lett. 91

      Pages: 23904-23904

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nondestructive micropatterning of living animal cells using focused femtosecond laser-induced impulsive force2007

    • Author(s)
      Takahiro Kaji, Syoji Ito, Hiroshi Miyasaka, Yoichiroh Hosokawa, Hiroshi Masuhara, Chisa Shukunami, and Yuji Hiraki
    • Journal Title

      Appt.Phys.Lett. Vol.91,No.2

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single Cell Control Based on Femtosecond Laser-induced Nonlinear Phenomena2007

    • Author(s)
      Yoichiroh Hosokawa, Ryohei Yasukuni, Takayuki Kaji, Atsushi Yamaguchi, Seriyalguchi, Tsuyoshi Asahi, and Hiroshi Masuhara
    • Journal Title

      The Review of Laser Engineering (Japanese) Vol.35,No.7

      Pages: 430-435

    • NAID

      10019524725

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 第58回応用物理学関係連合講演会2011

    • Author(s)
      細川陽一郎
    • Organizer
      フェムト秒レーザー誘起衝撃力による培養筋芽細胞の過渡力学応答の蛍光イメージング解析
    • Place of Presentation
      神奈川(地震により中止)
    • Year and Date
      2011-03-24
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による培養筋芽細胞の過渡力学応答の蛍光イメージング解析2011

    • Author(s)
      細川陽一郎
    • Organizer
      第58回 応用物理学関係連合講演会
    • Place of Presentation
      神奈川工科大学(神奈川県)(開催予定が中止となり講演予稿集で発表)
    • Year and Date
      2011-03-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 液中レーザプロセスによる細胞培養環境場での神経突起誘導2011

    • Author(s)
      山本英明
    • Organizer
      第58回 応用物理学関係連合講演会
    • Place of Presentation
      神奈川工科大学(神奈川県)(開催予定が中止となり講演予稿集で発表)
    • Year and Date
      2011-03-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 第52回日本植物生理学会年会2011

    • Author(s)
      細川陽一郎
    • Organizer
      Development of manipulation and stimulation methods for single plant cells utilizing femtosecond
    • Place of Presentation
      宮城(招待講演)(地震により中止)
    • Year and Date
      2011-03-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Development of manipulation and stimulation methods for single plant cells utilizing femtosecond laser2011

    • Author(s)
      細川陽一郎
    • Organizer
      第52回日本植物生理学会年会
    • Place of Presentation
      東北大学(宮城県)(招待講演 開催予定が中止となり要旨集で発表)
    • Year and Date
      2011-03-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] レーザー学会学術講演会第31回年次大会2011

    • Author(s)
      平岡章宏, 細川陽一郎
    • Organizer
      フェムト秒レーザー誘起衝撃力を用いた培養動物細胞の過渡力学応答の検討
    • Place of Presentation
      東京
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] レーザー学会学術講演会第31回年次大会2011

    • Author(s)
      細川陽一郎
    • Organizer
      フェムト秒レーザー誘起マイクロ津波による細胞操作
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザー誘起マイクロ津波による細胞操作2011

    • Author(s)
      細川陽一郎
    • Organizer
      レーザー学会学術講演会第31回年次大会
    • Place of Presentation
      電気通信大学(大阪府)(招待講演)
    • Year and Date
      2011-01-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力を用いた培養動物細胞の過渡力学応答の検討2011

    • Author(s)
      平岡章宏
    • Organizer
      レーザー学会学術講演会第31回年次大会
    • Place of Presentation
      電気通信大学(大阪府)
    • Year and Date
      2011-01-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 原子間力顕微鏡を用いた水中を伝搬するフェムト秒レーザー誘起応力波の解析2010

    • Author(s)
      細川陽一郎
    • Organizer
      第408回レーザー学会研究会
    • Place of Presentation
      尾道商業会議所記念館(広島県)
    • Year and Date
      2010-11-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力を利用した神経-マスト細胞間の接着力の時間変化の評価2010

    • Author(s)
      飯野敬矩
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学(宮城県)
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 第71回応用物理学会学術講演会2010

    • Author(s)
      飯野敬矩, 細川陽一郎
    • Organizer
      フェムト秒レーザー誘起衝撃力と原子間力顕微用を利用した神経-マスト細胞間接着の力学的評価
    • Place of Presentation
      長崎
    • Year and Date
      2010-09-14
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力と原子間力顕微用を利用した神経-マスト細胞間接着の力学的評価2010

    • Author(s)
      飯野敬矩
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学(長崎県)
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] フェムト秒レーザーを用いた液中プロセスによる細胞接着領域の作製と異種細胞の配置22010

    • Author(s)
      松井愛
    • Organizer
      第71回応用物理学会学術講演会
    • Place of Presentation
      長崎大学(長崎県)
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 第73回レーザ加工学会2010

    • Author(s)
      細川陽一郎
    • Organizer
      超短パルスレーザ誘起衝撃力による細胞操作とその定量評価
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-05-25
    • Related Report
      2010 Final Research Report
  • [Presentation] 超短パルスレーザ誘起衝撃力による細胞操作とその定量評価2010

    • Author(s)
      細川陽一郎
    • Organizer
      第73回レーザ加工学会
    • Place of Presentation
      大阪大学(大阪府)(招待講演)
    • Year and Date
      2010-05-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 2010年春季 第57回 応用物理学関係連合講演会2010

    • Author(s)
      飯野敬矩, 細川陽一郎, 萩山満, 伊藤彰彦, 岡野和宣, 増原宏
    • Organizer
      フェムト秒レーザー誘起衝撃力による神経-マスト細胞間接着の力学的評価
    • Place of Presentation
      神奈川
    • Year and Date
      2010-03-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 2010年春季第57回 応用物理学関係連合講演会2010

    • Author(s)
      細川陽一郎, 飯野敬矩, 萩山満, 岡野和宣, 伊藤彰彦, 増原宏
    • Organizer
      原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム4-上皮細胞間の接着力測定-
    • Place of Presentation
      神奈川
    • Year and Date
      2010-03-17
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力が誘起する原子間力顕微鏡探針の過渡振動の解明2010

    • Author(s)
      飯野敬矩, 細川陽一郎, 増原宏
    • Organizer
      平成21年度電気学会光・量子デバイス研究会
    • Place of Presentation
      尾道商業会議所記念館(広島)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザーが水中に誘起する局所応力波の非接触計測2010

    • Author(s)
      細川陽一郎, 飯野敬矩, 増原宏
    • Organizer
      平成21年度電気学会光・量子デバイス研究会
    • Place of Presentation
      尾道商業会議所記念館(広島)
    • Year and Date
      2010-03-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起応力波により刺激された細胞の応答評価2010

    • Author(s)
      平岡章宏, 飯野敬矩, 細川陽一郎, 古野忠秀, 岡野和秀, 萩山満, 伊藤彰彦, 増原宏
    • Organizer
      2010年春季 第57回 応用物理学関係連合講演会
    • Place of Presentation
      東海大学(神奈川)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム4-上皮細胞間の接着力測定-2010

    • Author(s)
      細川陽一郎, 飯野敬矩, 萩山満, 岡野和宣, 伊藤彰彦, 増原宏
    • Organizer
      2010年春季 第57回 応用物理学関係連合講演会
    • Place of Presentation
      東海大学(神奈川)
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザーを用いた液中プロセスによる細胞接着領域の作製と異種細胞の配置2010

    • Author(s)
      松井愛, 前澤安代, 松原美絵, 細川陽一郎, 増原宏, 岡野和宣
    • Organizer
      2010年春季 第57回 応用物理学関係連合講演会
    • Place of Presentation
      東海大学(神奈川)
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起衝撃力による神経-マスト細胞間接着の力学的評価2010

    • Author(s)
      飯野敬矩, 細川陽一郎, 萩山満, 伊藤彰彦, 岡野和宣, 増原宏
    • Organizer
      2010年春季 第57回 応用物理学関係連合講演会
    • Place of Presentation
      東海大学(神奈川)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 2009年秋季 第70回応用物理学会学術講演会2009

    • Author(s)
      細川陽一郎, 飯野敬矩, 萩山満, 伊藤彰彦, 岡野和宣, 増原宏
    • Organizer
      原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム3-セル凝集アッセイとの比較検討
    • Place of Presentation
      富山
    • Year and Date
      2009-09-08
    • Related Report
      2010 Final Research Report
  • [Presentation] CREST講演会「光で拓く細胞から染色体の世界」2009

    • Author(s)
      細川陽一郎
    • Organizer
      基礎医学のためのフェムト秒レーザー衝撃力による異種細胞間の個別接着力評価
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2009-08-20
    • Related Report
      2010 Final Research Report
  • [Presentation] CREST講演会「光で拓く細胞から染色体の世界」2009

    • Author(s)
      細川陽一郎
    • Organizer
      基礎医学のためのフェムト秒レーザー衝撃力による異種細胞間の個別接着力評価
    • Place of Presentation
      東京
    • Year and Date
      2009-08-20
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] 基礎医学のためのフェムト秒レーザー衝撃力による異種細胞間の個別接着力評価2009

    • Author(s)
      細川陽一郎
    • Organizer
      平成21年度電気学会 センサ・マイクロマシン部門総合研究会
    • Place of Presentation
      法政大学(東京)
    • Year and Date
      2009-08-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] Femtosecond "Laser Tsunami" Mamipulation for Single Living Cells in Solution2009

    • Author(s)
      Hiroshi Masuhara, Yoichiroh Hosokawa
    • Organizer
      Spring Annual Meeting of the Korean Chemical Society, A Special Symposium of Physical Chemistry Division "Physical Chemistry for Biological Application"
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 2009年春季第56回応用物理学関係連合講演会2009

    • Author(s)
      細川陽一郎, 飯野敬矩, 岡野和宣, 増原宏
    • Organizer
      原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム2
    • Place of Presentation
      茨城
    • Year and Date
      2009-03-30
    • Related Report
      2010 Final Research Report
  • [Presentation] The 25th Progress In Electromagnetics Research Symposium (PIERS 2009)2009

    • Author(s)
      Y.Hosokawa, A.Ito, K.Okano, Y.Murakami, H.Masuhara.
    • Organizer
      Estimation of local force of biological cellular adhesion by Femtosecond Laser Micro "Tsunami"
    • Place of Presentation
      Beijing China
    • Year and Date
      2009-03-23
    • Related Report
      2010 Final Research Report
  • [Presentation] Photonics West LASE 20092009

    • Author(s)
      Y.Hosokawa, K.Okano, H.Masuhara.
    • Organizer
      Local force detection of femtosecond laser-induced stress wave using atomic force microscope
    • Place of Presentation
      California USA
    • Year and Date
      2009-01-24
    • Related Report
      2010 Final Research Report
  • [Presentation] The 5th International Congress on Laser Advanced Materials Processing (LAMP2009)2009

    • Author(s)
      Y.Hosokawa, H.Masuhara, A.Ito.
    • Organizer
      Cell Detachment Induced by Femtosecond Laser "Tsunami" and the Force Estimation Using Atomic Force Microscope
    • Place of Presentation
      兵庫
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザーを用いた細胞アレイ用基板上での個別細胞配置と細胞間接続2009

    • Author(s)
      岡野和宣, 于大衛, 前澤安代, 松井愛,細 川陽一郎,松 原美絵, 吉良敦史, 増原宏
    • Organizer
      第10回計測自動制御学会 システムインテグレーション部門講演会
    • Place of Presentation
      芝浦工業大学(東京)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細胞アレイ基板上でのフェムト秒レーザーを用いた個別細胞配置と細胞間接着誘起2009

    • Author(s)
      岡野和宣, 于大衛, 前澤安代, 細川陽一郎, 松井愛, 吉良敦史, 増原宏
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 自己組織化単分子膜修飾とそのパターニングによるチップ上での細胞配置および培養制御2009

    • Author(s)
      吉良敦史, 岡野和宣, 細川陽一郎, 内藤晶, 増原宏
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸国際会議場(兵庫)
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザーによる液中における細胞基板の表面改質と細胞間接合形成2009

    • Author(s)
      岡野和宣, 前澤安代, 細川陽一郎, 吉良敦史, 松原美絵, 不破耕, 増原宏
    • Organizer
      2009年秋季 第70回応用物理学会学術講演会
    • Place of Presentation
      富山大学(富山)
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起応力による細胞剥離過程:細胞外マトリックスの可視化による解明2009

    • Author(s)
      前澤安代, 細川陽一郎, 岡野和宣, 松原美絵, 増原宏
    • Organizer
      2009年秋季 第70回応用物理学会学術講演会
    • Place of Presentation
      富山大学(富山)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 原子問力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム3-セル凝集アッセイとの比較検討-2009

    • Author(s)
      細川陽一郎, 飯野敬矩, 萩山満, 伊藤彰彦, 岡野和宣, 増原宏
    • Organizer
      2009年秋季 第70回応用物理学会学術講演会
    • Place of Presentation
      富山大学(富山)
    • Related Report
      2009 Annual Research Report
  • [Presentation] AFMを用いたフェムト秒レーザー誘起局所衝撃力とそのバイオ応用2009

    • Author(s)
      細川陽一郎
    • Organizer
      CREST講演会「光で拓く細胞から染色体の世界」
    • Place of Presentation
      理研 大河内記念ホール(埼玉)
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザ「を用いた培養液中細胞間ジャンクションの形成2009

    • Author(s)
      岡野和宣, 前澤安代, 細川陽一郎, 松原美絵, 増原宏, 吉良敦史
    • Organizer
      理研シンポジ-ウム「階層横断生命科学-異分野融合的研究の新展開にむけて-」
    • Place of Presentation
      東京工科大学(東京)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 自己組織化単分子膜のパターニングで作製した基板を用いた三次元細胞培養の検討2009

    • Author(s)
      吉良敦史, 不破耕, 岡野和宣, 細川陽一郎, 内藤晶, 増原宏
    • Organizer
      平成21年度電気学会 センサ・マイクロマシン部門総合研究会
    • Place of Presentation
      東京工科大学(東京)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Micro-channel fabrication by femtosecond laser to arrange neuronal cells of multi-electrode arrays2009

    • Author(s)
      Chie Hosokawa, Mariko Suzuki, Takahisa Taguchi, Ai Kiyohara, Suguru N.Kudoh, Yoichiroh Hosokawa, Kazunori Okano, HiroshiMasuhara
    • Organizer
      the 10th annual Conference on Laser Ablation (COLA 2009)
    • Place of Presentation
      Singapore (Singapore)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Transient oscillation of AFM cantilever induced by femtosecond laser-induced stress2009

    • Author(s)
      Takanori Iino, Yoichiroh Hosokawa, Kazunori, Okano, Hiroshi Masuhara
    • Organizer
      the 10th annual Conference on Laser Ablation (COLA 2009)
    • Place of Presentation
      Singapore (Singapore)
    • Related Report
      2009 Annual Research Report
  • [Presentation] In situ cell detachment from a substrate by femtosecond laser-induced stresswave2009

    • Author(s)
      Yasuyo Maezawa, Yoichiroh Hosokawa, Kazunori Okano, Mie Matsubara, Hiroshi Masuhara
    • Organizer
      the 10th annual Conference on Laser Ablation (COLA 2009)
    • Place of Presentation
      Singapore (Singapore)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Femtosecond Laser-induced Stress on Live Myocyte Cells2009

    • Author(s)
      Yung-En Kuo, Cheng-Chi Wu, Yoichiroh Hosokawa, Yasuyo Maezawa, Kazunori Okano, Hiroshi Masuhara, Fu-Jen Kao
    • Organizer
      the 10th annual Conference on Laser Ablation (COLA 2009)
    • Place of Presentation
      Singapore (Singapore)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Bio-Application of femtosecond laser-induced impulsive force : Elucidation of intercellular adhesion in physiological cultures2009

    • Author(s)
      Yoichiroh Hosokawa
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecular/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fluorescence visualization of cell detachment process from a substrate by femtosecond laser Tsunami"2009

    • Author(s)
      Yasuyo Maezawa, Yoichiroh Hosokawa, Kazunori Okano, Mie Matsubara, Hiroshi Masuhara
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecular/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] A trial to reveal cell activity upon stimulation by femtosecond laser-induced stress wave : Fluorescence imaging of Calcium indicator in individual cells2009

    • Author(s)
      Akihiro Hiraoka, Takanori Iino, Yoichiroh Hosokawa, Tadahide Furuno, Kazunori Okano, Mitsuru Hagiyama, Akihiko Ito, Hiroshi Masuhara
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecular/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quantitative analysis of femtosecond laser-induced impulsive force utilizing atomic force microscope for estimating intercellular adhesion strength2009

    • Author(s)
      Takanori Iino, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecular/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fabrication of cell-array platform by femtosecond laser process in culture medium2009

    • Author(s)
      Ai Matsui, Yasuyo Maezawa, Yoichiroh Hosokawa, Kazunori Okano, Mie Matsubara, Hiroshi Masuhara
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecular/Nano Science
    • Place of Presentation
      Hsinchu, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] In-Situ Arrangement of Living Cells on a Fabricated Surface by Laser Micro Tsunami2009

    • Author(s)
      Kazunori Okano, Yasuyo Maezawa, Yoichiroh. Hosokawa, Atsushi Kira, Mie.Matsubara, Hiroshi.Masuhara
    • Organizer
      The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (JAS 2009)
    • Place of Presentation
      Jeju, Korea
    • Related Report
      2009 Annual Research Report
  • [Presentation] Cell Detachment Induced by Femtosecond Laser "Tsunami" and the Force Estimation Using Atomic Force Microscope2009

    • Author(s)
      Yoichiroh Hosokawa, Hiroshi Masuhara, Akihiko Ito
    • Organizer
      The 5th International Congress on Laser Advanced Materials Processing (LAMP2009)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] フェムト秒レーザー誘起応力により選別きれた細胞形態の評価2009

    • Author(s)
      前澤安代, 細川陽一郎, 岡野和宣, 松原美絵, 増原宏
    • Organizer
      2009年春季第56回応用物理学関係連合講演会
    • Place of Presentation
      筑波大学(茨城県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 多点電極アレイ上の神経細胞パターニング2009

    • Author(s)
      細川千絵, 工藤卓, 鈴木真理子, 清原藍, 細川陽一郎, 岡野和宣, 増原宏, 田口隆久
    • Organizer
      2009年春季第56回応用物理学関係連合講演会
    • Place of Presentation
      筑波大学(茨城県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム1-水中で発生するフェムト秒レーザー誘起過渡応力の評価-2009

    • Author(s)
      飯野敬矩, 細川陽一郎, 岡野和宣, 増原宏
    • Organizer
      2009年春季第56回応用物理学関係連合講演会
    • Place of Presentation
      筑波大学(茨城県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 原子間力顕微鏡によるフェムト秒レーザー津波の及ぼす局所応力測定システム22009

    • Author(s)
      細川陽一郎, 飯野敬矩, 岡野和宣, 増原宏
    • Organizer
      2009年春季第56回応用物理学関係連合講演会
    • Place of Presentation
      筑波大学(茨城県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Laser Tsunami Crystallization and Laser Trapping Crystallization : A Challenge for Molecular Materials Study2009

    • Author(s)
      Hiroshi Mastihara, Yoichiroh Hososkawa, Teruki Sugiyama, Atsushi Miura, And Takaynki Uwada
    • Organizer
      The 2nd Japan-Taiwan Joint Symposium on Organized Nanomaterials and Nanostructures Related to Photoscience
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Local Force Detection of Femtosecond Laser-induced Stress Wave Using Atomic Force Microscope2009

    • Author(s)
      Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara
    • Organizer
      Photonics West LASE 2009
    • Place of Presentation
      San Jose, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] Estimation of local force of biological cellular adhesion by Femtosecond Laser Micro "Tsunami"2009

    • Author(s)
      Yoichiroh Hosokawa, Akihiko Ito, Kazunori Okano, Yoshinori Murakami, Hiroshi Masuhara
    • Organizer
      The 25th Progress In Electromagnetics Research Symposium (PIERS 2009)
    • Place of Presentation
      Beijing, China
    • Related Report
      2008 Annual Research Report
  • [Presentation] 第31回日本生物学会年会第81回日本生化学会大会合同大会2008

    • Author(s)
      細川陽一郎
    • Organizer
      フェムト秒レーザー衝撃波を利用した新しい細胞操作と生命科学研究への展開
    • Place of Presentation
      兵庫(招待講演)
    • Year and Date
      2008-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] フェムト秒レーザー衝撃波を利用した新しい細胞操作と生命科学研究への展開2008

    • Author(s)
      細川陽一郎
    • Organizer
      第31回日本生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      兵庫
    • Year and Date
      2008-12-09
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] 6th International Conference on Photo-Excited Processes and Applications (ICPEPA2008)2008

    • Author(s)
      Y.Hosokawa, H.Masuhara.
    • Organizer
      Micro-activation of cultured animal cells by focused femtosecond laser
    • Place of Presentation
      北海道(招待講演)
    • Year and Date
      2008-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Micro-activation of Cultured Animal Cells by Focused Femtosecond Laser2008

    • Author(s)
      Y. Hosokawa, H. Masuhara
    • Organizer
      6th International Conference on Photo-Excited Processes and Applications (ICPEPA2008)
    • Place of Presentation
      北海道
    • Year and Date
      2008-09-09
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] 2008年秋季 第69回応用物理学会学術講演会2008

    • Author(s)
      細川陽一郎, 岡野和宣, 増原宏
    • Organizer
      原子間力顕微鏡を用いたフェムト秒レーザーマイクロ津波の局所応力計測システムの開発
    • Place of Presentation
      愛知
    • Year and Date
      2008-09-02
    • Related Report
      2010 Final Research Report
  • [Presentation] XXI Congress and General Assembly of the International Union of Crystallography2008

    • Author(s)
      Y.Hosokawa, M.Kashii, H.Yoshikawa, H.Adachi, Y.Mori, H.Masuhara.
    • Organizer
      Femtosecond laser etching of protein crystal to process and to isolate the single crystal
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2008-08-23
    • Related Report
      2010 Final Research Report
  • [Presentation] 第55回応用物理学関係連合講演会2008

    • Author(s)
      細川陽一郎、瀧澤典子、宇和田貴之、岡野和宣、増原宏
    • Organizer
      集光フェムト秒レーザーを利用した生体材料のマイクロパターニング4-動物培養細胞の分化誘導過程による細胞非破壊性の評価-
    • Place of Presentation
      千葉
    • Year and Date
      2008-03-27
    • Related Report
      2010 Final Research Report
  • [Presentation] フォトニック・ バイオメディシン最前線:ここまできたレーザ医学・生物学(III)2008

    • Author(s)
      細川 陽一郎
    • Organizer
      「フェムト秒レーザによる細胞の非線形プロセシング」電気学会光・量子デバイス研究会
    • Place of Presentation
      慶応義塾大学日吉キャンパス(東京都)
    • Year and Date
      2008-02-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] レーザー学会学術講演会第28回年次大会2008

    • Author(s)
      細川陽一郎、瀧澤典子、宇和田貴之、岡野和宣、増原宏
    • Organizer
      集光フェムト秒レーザーによるラット褐色腫由来細胞のパターニング過程
    • Place of Presentation
      愛知
    • Year and Date
      2008-01-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Photonics West BiOS 20082008

    • Author(s)
      Y.Hosokawa, Y.Jiang, I.Oh, N.Takizawa, T.Uwada, K.Okano, H.Masuhara,
    • Organizer
      Femtosecond laser manipulation techniques for individual patterning of biological micro-object
    • Place of Presentation
      California USA
    • Year and Date
      2008-01-19
    • Related Report
      2010 Final Research Report
  • [Presentation] パーフルオロアルキル系単分子膜上でのフェムト秒レーザーによる細胞配置制御2008

    • Author(s)
      岡野和宣, 吉良敦史, 細川陽一郎, 不破耕, 増原宏
    • Organizer
      2008年秋季第69回応用物理学会学術講演会
    • Place of Presentation
      中部大学(愛知県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 原子間力顕微鏡を用いたフェムト秒レーザーマイクロ津波の局所応力計測システムの開発2008

    • Author(s)
      細川陽一郎, 岡野和宣, 増原宏
    • Organizer
      2008年秋季第69回応用物理学会学術講演会
    • Place of Presentation
      中部大学(愛知県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 亜鉛ポルフィリン化合物の単一ナノ粒子分光2008

    • Author(s)
      宇和田貴之, 細川陽一郎, 岡野和宣, 増原宏
    • Organizer
      第2回分子科学討論会2008福岡
    • Place of Presentation
      福岡国際会議場
    • Related Report
      2008 Annual Research Report
  • [Presentation] 鍼通電刺激によるミオスタチン遺伝子発現制御と骨格筋幹細胞の増殖制御2008

    • Author(s)
      大田美香、細川陽一郎、池宗佐知子、伊藤彫彦、三浦研爾、菅野亜紀、宮本俊和、高岡裕
    • Organizer
      第31回日本生物学会年会第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] フェムト秒レーザー衝撃波を利用した新しい細胞操作と生命科学研究への展開2008

    • Author(s)
      細川陽一郎
    • Organizer
      第31回日本隼物学会年会第8手回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 化学表面修飾と微細加工による生体分子なちびに細胞の高精度集積化技術-2008

    • Author(s)
      吉良敦史、岡野和宣、細川陽一郎、内藤晶、不破耕、湯山純平、増原宏
    • Organizer
      第31回日本生物学会年会第81回日本生化学会大会合同大会(BMB 2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] オールウェットレーザーナノプロセスによる細胞及び生体材料の集積化(5)-パーフルオロアルキル基板上でのフェムート秒レーザー欄一細胞プロセス2008

    • Author(s)
      岡野和宣、細川陽一郎、吉良敦史、不破耕、湯山純平、内藤晶、増原宏
    • Organizer
      第31回日本生物学会年会第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Laser Fabrication of Nanoparticles and Crystals in Solution2008

    • Author(s)
      Teruki Sugiyama, Tsuyoshi Asahi, Ken-ichi Yuyama, Hiroki Takeuchi, Hyeon-Gu Jeon, Yoichiroh Hosokawa, and Hiroshi Masuhara
    • Organizer
      3rd Pacific International Conference on Applications of Laser and Optics
    • Place of Presentation
      Peking, P. R. China
    • Related Report
      2008 Annual Research Report
  • [Presentation] Laser Micro-Patterning of Neuronal Network on Multi-Electrode Arrays2008

    • Author(s)
      Chie Hosokawa, Suguru N. Kudoh, Ai Kiyohara, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara, Takahisa Taguchi
    • Organizer
      6th International Meeting on Substrate-Integrated Micro-Electrode Arrays (MEA-Meeting 2008)
    • Place of Presentation
      Reutlingen, Germany
    • Related Report
      2008 Annual Research Report
  • [Presentation] Femtosecond Laser Etching of Protein Crystal to Process and to Isolate the Single Crystal2008

    • Author(s)
      Yoichiroh Hosokawa, Masafumi Kashii, Hiroshi Y. Yoshikawa, Hiroaki Adachi, Yusuke Mori, Hiroshi Masuhara
    • Organizer
      XXI Congress and General Assembly of the International UNion of Crystallography
    • Place of Presentation
      Osaka, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Protein crystallization by femtosecond laser ablation in supersaturated solution2008

    • Author(s)
      Horoshi Y. Yoshikawa, Yoichiroh Hosokawa, R. Murai, Gen Sazald, T. Kitatani, S. Maki, S. Sugiyama, Hiroshi Masuhara, H. Adachi, T. Inoue, H. Matsumura, K. Takano, S. Murakami, T. Sasaki, Yusuke Mori
    • Organizer
      XXIInd IUPAC on Photochemistry
    • Place of Presentation
      Gothenburg, Sweden
    • Related Report
      2008 Annual Research Report
  • [Presentation] Spectroscopic study and organic molecular sensing application of single porphyrin nanoparticles2008

    • Author(s)
      Takayuki Uwada, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara
    • Organizer
      XXIInd IUPAC on Photochemistry
    • Place of Presentation
      Gothenburg, Sweden
    • Related Report
      2008 Annual Research Report
  • [Presentation] Micro-activation of Cultured Animal Cells by Focused Femtosecond Laser2008

    • Author(s)
      Chie Hosokawa, Suguru N. Kudoh, Ai Kiyohara, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara, Takahisa Taguchi
    • Organizer
      6th International Conference on Photo-Excited Processes and Applications (ICPEPA 2008)
    • Place of Presentation
      6th International Conference on Photo-Excited Processes and Applications (ICPEPA 2008)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Micro-activation of Cultured Animal Cells by Focused Femtosecond Laser2008

    • Author(s)
      Yoichiroh Hosokawa, Hiroshi Masuhara
    • Organizer
      6th International Conference on Photo-Excited Processes and Applications (ICPEPA 2008)
    • Place of Presentation
      Sapporo, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] On-Chip integration of Biomolecules and Cells by Chemical Surface Modification and Microfabrication Technologies2008

    • Author(s)
      Atsushi Kira, Kazunori Okano, Yoichiroh Hosokawa, Hiroshi Masuhara, Akira Naito, Koh Fuwa, Jyunei Yuyama
    • Organizer
      4th Vacuum and Surface Sciences Conference of Asia and Australia (VASSCAA-4)
    • Place of Presentation
      MatSue, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Array Arrangement of Living Cells on Self-assembled Monolayer Pattern Chip with Femtosecond Laser Inducing Mechanical Force "micro tsunami"2008

    • Author(s)
      Atsushi Kira, Kazunori Okano, Yoichiroh Hosokawa, Koh Fuwa, Jyunpei Yuyama, Akira Naito, Hiroshi Masuhara
    • Organizer
      TREE International Symposium on Micro-NanoMechatronics and Human Science (MHS 2008)
    • Place of Presentation
      Nagoya, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Dynamics, Mechanism, and Application of Laser Ablation of Molecular and Bio Systems2008

    • Author(s)
      Hiroshi Masuhara, Yoichiroh Hosokawa, Teruki Sugiyama, and Kazunori Okano
    • Organizer
      The 8th GIST/NIST Joint Aymposium on Advanced Materials
    • Place of Presentation
      Ikoma, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Individual Sorting of Animal Cells by Femtosecond Laser Induced-Stress Wave2008

    • Author(s)
      Yasuyo Maezawa, Yoichiroh Hosokawa, Kazunori Okano, Mie Matsubara, Hiroshi Masuhara
    • Organizer
      The 8th GIST/NIST Joint Aymposium on Advanced Materials
    • Place of Presentation
      Ikoma, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Local Stimulation of Live Cells by Femtosecond Laser-induced Stress2008

    • Author(s)
      Cheng-Chi Wu, Yung-En Kuo, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara, Fu-Jen Kao
    • Organizer
      The International Conference on Laser Applications in Life Sciences 2008 (LALS 2008)
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Local Force Analysis of Transient Stress Induced by Focusing Femtosecond Laser in Water : Toward Its Application for Biotechnology2008

    • Author(s)
      Takanori Iino, Yoichiroh Hosokawa, Kazunori Okano, Hiroshi Masuhara
    • Organizer
      The International Conference on Laser Applications in Life Sciences 2008 (LALS 2008)
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Femtosecond Laser Manipulation Techniques for Individual Patterning of Biological Micro-object2008

    • Author(s)
      Yoichiroh Hosokawa, Yugiang Jiang, samu Oh, Noriko Takizawa, Takayuki Uwada, Kazunori Okano. Hiroshi Masuhara
    • Organizer
      Photonics West BiOS 2008
    • Place of Presentation
      San Jose,California USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Organic molecular sensing by single metal porphyrin nanoparticles2008

    • Author(s)
      T. Uwada, Y. Hosokawa, N. Takizawa, K.Okano, H. Masuhara
    • Organizer
      Photonics West BiOS 2008
    • Place of Presentation
      San Jose,California USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Smart bombing a single targeted cell with femtogram order reagents using laser-induced shockwave technique2008

    • Author(s)
      K. Okano, N. Takizawa, T. Uwada, Y. Hosokawa, H. Masuhara
    • Organizer
      Photonics West BiOS 2008
    • Place of Presentation
      San Jose,California USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Viability evaluation of culture cells patterned by femtosecondl aser-induced impulsive force2008

    • Author(s)
      N. Takizawa, K. Okano, T. Dwada, Y. Hosokawa, H. Masuhara
    • Organizer
      Photonics West BiOS 2008
    • Place of Presentation
      San Jose,California USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] 単一ポルフィリンナノ粒子の分光と有機分子検出センサーへの応用 (2)2008

    • Author(s)
      宇和田 貴之、細川 陽一郎、瀧澤 典子、岡野 和宣、増原 宏
    • Organizer
      第55回応用物理学関係連合講演会
    • Place of Presentation
      日本大学船橋キャンパス
    • Related Report
      2007 Annual Research Report
  • [Presentation] 「高速画像計測によるアントラセンのフェムト秒パルス誘起結晶化ダイナミクスの研究」2007年光化学討論会、信州大学、2007/9/26-282008

    • Author(s)
      細川 陽一郎、中村 和彦、増原 宏
    • Organizer
      2007年光化学討論会
    • Place of Presentation
      信州大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] 集光フェムト秒レーザーによるラット褐色腫由来細胞のパターニング過程2008

    • Author(s)
      細川 陽一郎、瀧澤 典子、宇和田 貴之、岡野 和宣、増原 宏
    • Organizer
      レーザー学会学術講演会第28回年次大会
    • Place of Presentation
      名古屋国際会議場
    • Related Report
      2007 Annual Research Report
  • [Presentation] 集光フェムト秒レーザーを利用した生体材料のマイクロパターニング4-動物培養細胞の分化誘導過程による細胞非破壊性の評価-2008

    • Author(s)
      細川 陽一郎、瀧澤 典子、宇和 田貴之、岡野 和宣、増原 宏
    • Organizer
      第55回応用物理学関係連合講演会
    • Place of Presentation
      日本大学船橋キャンパス
    • Related Report
      2007 Annual Research Report
  • [Presentation] 単一ポルフィリンナノ粒子の分光と有機分子検出センサーへの応用(2)2008

    • Author(s)
      宇和田 貴之、細川 陽一郎、瀧澤 典子、岡野 和宣、増原 宏
    • Organizer
      第55回応用物理学関係連合講演会
    • Place of Presentation
      日本大学船橋キャンパス
    • Related Report
      2007 Annual Research Report
  • [Presentation] フェムト秒レーザーによる個別細胞パターニングプロセス2007

    • Author(s)
      細川 陽一郎、宇和田 貴之、瀧澤 典子、岡野 和宣、増原 宏
    • Organizer
      レーザ学会第369回研究会
    • Place of Presentation
      徳島大学
    • Year and Date
      2007-12-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] 第30回日本分子生物学会年会2007

    • Author(s)
      細川陽一郎、瀧澤典子、宇和田貴之、岡野和宣、増原宏
    • Organizer
      オールウエットレーザーナノプロセスによる細胞および生体材料の集積化(1)-高速カメラを用いたフェムト秒レーザー誘起細胞転写過程の観察-
    • Place of Presentation
      神奈川
    • Year and Date
      2007-12-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 2007年光化学討論会2007

    • Author(s)
      細川陽一郎、中村和彦、増原宏
    • Organizer
      高速画像計測によるアントラセンのフェムト秒パルス誘起結晶化ダイナミクスの研究
    • Place of Presentation
      長野
    • Year and Date
      2007-09-26
    • Related Report
      2010 Final Research Report
  • [Presentation] The 9th annual Conference on Laser Ablation2007

    • Author(s)
      Y.Hosokawa, J.Takabayashi, H.Masuhahra, K.Fujiyama, T.Seki.
    • Organizer
      Nondestructive Separation of Fission Yeast Cells by Femtosecond Laser-induced Impulsive Force
    • Place of Presentation
      Tenerife, Spain
    • Year and Date
      2007-09-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Nanoparticles injection into single animal cells by femtosecond laser-induced impulsive force2007

    • Author(s)
      A.Yamaguchi, Y.Hosokawa, G.Louit, T.Asahi, H.Masuhara, C.Shukunami, Y.Hiraki.
    • Place of Presentation
      Tenerife, Spain
    • Year and Date
      2007-09-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 第68回応用物理学会学術講演会2007

    • Author(s)
      細川陽一郎、梶貴博、宇和田貴之、瀧澤典子、岡野和宣、伊都将司、宮坂博、増原宏
    • Organizer
      集光フェムト秒レーザーを利用した生体材料のマイクロパターニング3-フェムト秒レーザー誘起衝撃波・キャビテーションバブルの細胞非破壊性の実証-
    • Place of Presentation
      北海道
    • Year and Date
      2007-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] All Wet Femtosecond Laser Processing for Bio Application2007

    • Author(s)
      H. Masuhahra, Y. Hosokawa
    • Organizer
      Keio International Symposium on Photonics and Molecular Therapy
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cell Viability after Femtosecond Laser Ablation of Tissue2007

    • Author(s)
      Yoichiroh Hosokawa, Noriko Takizawa, Takayuki Uwada, Kazunori Okano, Hiroshi Masuhara
    • Organizer
      Keio International Symposium on Photonics and Molecular Therapy
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Femtosecond Laser Micro-injection of EGFP PIasmid into Singlc Animal Cell2007

    • Author(s)
      Yoichiroh Hosokawa, Seriya Iguchi, Yujl Hiraki, Chisa Shukunami, Hiroshi Masuhara
    • Organizer
      Keio International Symposium on Photonics and Molecular Therapy
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2007 Annual Research Report
  • [Presentation] Nondestructive Separation of Fission Yeast Cells by Femtosecond Laser-induced Impulsive Force2007

    • Author(s)
      Y. Hosokawa, J. Takabayashi, H. Masuhahra, K. Fujiyama, T. Seki
    • Organizer
      The 9th annual Conference on Laser Ablation
    • Place of Presentation
      Tenerife, Spain
    • Related Report
      2007 Annual Research Report
  • [Presentation] Nanoparticles Injection into Single Animal Cells by Femtosecond Laser-induced Impulsive Force2007

    • Author(s)
      Atsushi Yamaguchi, Yoichiroh Hosokawa, Guillaume Louit, Tsuyoshi Asahi. Hiroshi Masuhara. Chisa Shukunami, Yuji Hiraki
    • Organizer
      The 9th annual Conference on Laser Ablation
    • Place of Presentation
      Tenerife, Spain
    • Related Report
      2007 Annual Research Report
  • [Presentation] フェムト秒レーザーによる蛋白質結晶の非変性加工2007

    • Author(s)
      細川 陽一郎、吉川 洋史、安達 宏昭、森 勇介、佐々木 孝友、増原 宏
    • Organizer
      第68回レーザー加工学会
    • Place of Presentation
      大阪大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] 集光フェムト秒レーザーを利用した生体杉料のマイクロパターニング3-フェムト秒レーザー誘起衝撃波・キャビテーションバブルの細胞非破壊性の実証-2007

    • Author(s)
      細川 陽一郎、梶貴 博、宇和田 貴之、瀧澤 典子、岡野 和宣、伊都 将司、宮坂 博、増原 宏
    • Organizer
      第68回応用物理学会学術講演会
    • Place of Presentation
      北海道工業大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] 蛍光ラベルタンパク質を用いてのフェムト秒レーザー誘起核発生メカニズムの解析2007

    • Author(s)
      吉川 洋史、村井 良多、空洋 介、佐崎 元、細川 陽一郎、増原 宏、北谷 友也、牧祥、杉山 成、安達 宏昭、高野 和文、松村 浩由、村上 聡、井上 豪、森勇 介、佐々木 考友
    • Organizer
      第68回応用物理学会学術講演会
    • Place of Presentation
      北海道工業大学
    • Related Report
      2007 Annual Research Report
  • [Presentation] オールウエットレーザーナノプロセスによる細胞および生体材料の集積化(1)-高速カメラを用いたフェムト秒レーザー誘起細胞転写過程の観察-2007

    • Author(s)
      細川 陽一郎、瀧澤 典子、宇和田 貴之、岡野 和宣、増原 宏
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] オールウェットレーザーナノプロセスによる細胞および生体材料の集積化(2)-フェムト秒レーザープロセスによりパターニングしたPC12細胞の分化誘導過程-2007

    • Author(s)
      瀧澤 典子、岡野 和宣、宇和田 貴之、細川 陽一郎、増原 宏
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] オールウェット・ レーザーナノプロセスによる細胞及び生体材料の集積化(3)-ポルフィリン単一ナノ粒子を用いた生体分子の検出-2007

    • Author(s)
      宇和田 貴之、細川 陽一郎、瀧澤 典子、岡野 和宣、増原 宏
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] オールウェットレーザーナノプロセ冬による細胞及び生体材料の集積化(4)-フェムト秒レーザーによる非熱的爆触現象を利用した液中極微量試薬添加-2007

    • Author(s)
      岡野 和宣、瀧澤 典子、宇和田 貴之、細川 陽一郎、増原 宏
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2007 Annual Research Report
  • [Book] リアルタイム計測による生命現象の解析(第4章)フェムト秒レーザー誘起衝撃力を利用した細胞接着力の非接触計測2011

    • Author(s)
      細川陽一郎
    • Publisher
      シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Book] リアルタイム計測による生命現象の解析(第4章 フェムト秒レーザー誘起衝撃力を利用した細胞接着力の非接触計測)2011

    • Author(s)
      細川陽一郎
    • Publisher
      株式会社シーエムシー出版
    • Related Report
      2010 Annual Research Report
  • [Book] 光ナノ科学への招待2010

    • Author(s)
      長谷川晴哉, 細川陽一郎, 中嶋琢也
    • Publisher
      化学同人
    • Related Report
      2010 Final Research Report
  • [Book] 光ナノ科学への招待2010

    • Author(s)
      長谷川晴哉
    • Total Pages
      119
    • Publisher
      化学同人
    • Related Report
      2010 Annual Research Report
  • [Book] Molecular Nano Dynamics : Spectroscopic Methods and Nanostructures2009

    • Author(s)
      H.Masuhara, Y.Hosokawa, T.Uwada, G.Louit, T.Asahi, Wiley-VCH, Berlin
    • Publisher
      Chapter 28 : Femtosecond laser tsunami processing and light scattering spectroscopic imaging of single animal cells
    • Related Report
      2010 Final Research Report
  • [Book] Molecular Nano Dynamics : Spectroscopic Methods and Nanostructures vol.1 (Eds : H. Masuhara, H. Fukumura)2009

    • Author(s)
      Hiroshi Masuhara
    • Total Pages
      704
    • Publisher
      Berlin, Wiley-VCH, 2009
    • Related Report
      2008 Annual Research Report
  • [Book] バイオプロセスハンドブック(第3編第2章) フェムト秒レーザーが可能とする細胞内加工とそのイメージング2007

    • Author(s)
      細川陽一郎、安国良平、増原宏
    • Publisher
      NTS出版
    • Related Report
      2010 Final Research Report
  • [Book] 「バイオプロセスハンドブック」第3編第2章、NTS, pp.368-3762007

    • Author(s)
      細川 陽一郎、安国 良平、増原 宏
    • Total Pages
      9
    • Publisher
      フェムト秒レーザーが可能とする細胞内加工とそのイメージング
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページアドレス

    • URL

      http://hskw.jp

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://hskw.jp

    • Related Report
      2009 Self-evaluation Report
  • [Remarks]

    • URL

      http://hskw.jp/activity/Original.htm

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://mswebs.naist.jp/LABs/masuhara/index.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.hskw.jp/

    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] 試薬添加方法および試薬添加装置2008

    • Inventor(s)
      岡野和宣、細川陽一郎、宇和田貴之、増原宏
    • Industrial Property Rights Holder
      岡野和宣
    • Filing Date
      2008-05-23
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 試薬添加方法および試薬添加装置2008

    • Inventor(s)
      岡野和宣、細川陽一郎、宇和田貴之、増原宏
    • Industrial Property Rights Holder
      岡野和宣
    • Industrial Property Number
      2008-135869
    • Filing Date
      2008-05-23
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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