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Reconstruction of a bio-fluid dynamics model from the cellular level

Research Project

Project/Area Number 19686016
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Fluid engineering
Research InstitutionTohoku University

Principal Investigator

ISHIKAWA Takuji  Tohoku University, 大学院・工学研究科, 准教授 (20313728)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2009: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2008: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2007: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Keywords生物流体 / サスペンジョン / 微生物 / 赤血球 / 数理モデル / 生体流体力学 / 計算生体力学 / 血液 / レオロジー / 境界要素法 / ストークス流れ
Research Abstract

We had developed a numerical model of microorganisms, red blood cells and cancer cells by 2008. We also tried to model biological reaction of cells. In 2009, we utilized these models and computed many body interactions of cells in a suspension. Then we compiled a database for the stress field, diffusion tensor under various conditions. We also developed a mathematical model of these tensor values under simplified conditions. Besides, we develop a numerical model to solve population of bacteria in the human intestine by combining the cellular level models and the macroscopic models. We established a base for the multi-scale and multi-physics simulation for the microbial flora in the intestine.

Report

(5 results)
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (138 results)

All 2010 2009 2008 2007 Other

All Journal Article (74 results) (of which Peer Reviewed: 69 results) Presentation (53 results) Book (5 results) Remarks (6 results)

  • [Journal Article] A three-dimensional particle simulation of the formation and collapse of primary thrombus2010

    • Author(s)
      H.Kamada, K.Tsubota, M.Nakamura, S.Wada, T.Ishikawa, T.Yamaguchi
    • Journal Title

      International Journal for Numerical Methods in Biomedical Engineering 26

      Pages: 488-500

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ATP transport in saccular cerebral aneurysms at arterial bends2010

    • Author(s)
      Y.Imai, K.Sato, T.Ishikawa, A.Comerford, T.David, T.Yamaguchi
    • Journal Title

      Annals of Biomedical Engineering 38

      Pages: 927-934

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Suspension biomechanics of swimming microbes2009

    • Author(s)
      T.Ishikawa
    • Journal Title

      Journal of the Royal Society Interface 6

      Pages: 815-834

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dancing Volvox : Hydrodynamic bound states of swimming algae2009

    • Author(s)
      K.Drescher, K.Leptos, I.Tuval, T.Ishikawa, T.J.Pedley, R.E.Goldstein
    • Journal Title

      Physical Review Letters 102

      Pages: 168101-168101

    • NAID

      120003780457

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Can temporal fluctuation in spatial wall shear stress gradient initiate a cerebral aneurysm? A proposed novel hemodynamic index, the gradient oscillatory number (GON)2009

    • Author(s)
      Y.Shimogonya, T.Ishikawa, Y.Imai, N.Matsuki, T.Yamaguchi
    • Journal Title

      Journal of Biomechanics 42

      Pages: 550-554

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hemodynamic analysis of micro-circulation in malaria infection2009

    • Author(s)
      H.Kondo, Y.Imai, T.Ishikawa, K.Tsubota, T.Yamaguchi
    • Journal Title

      Annals of Biomedical Engineering 37

      Pages: 702-709

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Red blood cell motions in high-hematocrit blood flowing through a stenosed microchannel2009

    • Author(s)
      H.Fujiwara, T.Ishikawa, R.Lima, N.Matsuki, Y.Imai, H.Kaji, M.Nishizawa, T.Yamaguchi
    • Journal Title

      Journal of Biomechanics 42

      Pages: 838-843

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of unique biomedical education programs for engineers : REDEEM and ESTEEM projects2009

    • Author(s)
      N.Matsuki, M.Takeda, M.Yamano, Y.Imai, T.Ishikawa, T.Yamaguchi
    • Journal Title

      Advances in Physiology Education 33

      Pages: 91-97

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] An internet-based wearable watch-over system for elderly and disabled utilizing EMG and accelerometer2009

    • Author(s)
      M.Kishimoto, T.Yoshida, T.Hayasaka, D.Mori, Y.Imai, N.Matsuki, T.Ishikawa, T.Yamaguchi
    • Journal Title

      Technology and Health Care 17

      Pages: 121-131

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Measurement of individual red blood cell motions under high hematocrit conditions using a confocal micro-PTV system2009

    • Author(s)
      R.Lima, T.Ishikawa, Y.Imai, M.Takeda, S.Wada, T.Yamaguchi
    • Journal Title

      Annals of Biomedical Engineering 37

      Pages: 1546-1559

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Axisymmetric polydimethysiloxane microchannels for in vitro haemodynamic studies2009

    • Author(s)
      R.Lima, M.S.N.Oliveira, T.Ishikawa, H.Kaji, S.Tanaka, M.Nishizawa, T.Yamaguchi
    • Journal Title

      Biofabrication 1

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A realistic simulation of saccular cerebral aneurysm formation : focussing on a novel haemodynamic index the gradient oscillatory number2009

    • Author(s)
      Y.Shimogonya, T.Ishikawa, Y.Imai, N.Matsuki, T.Yamaguchi
    • Journal Title

      International Journal of Computational Fluid Dynamics 23

      Pages: 583-593

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a biologically inspired locomotion system for a capsule endoscope2009

    • Author(s)
      D.Hosokawa, T.Ishikawa, H.Morikawa, Y.Imai, T.Yamaguchi
    • Journal Title

      International Journal of Medical Robotics and Computer Assisted Surgery 5

      Pages: 471-478

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 準希薄微生物溶液における自己拡散シミュレーション-せん断流れの影響-2009

    • Author(s)
      石川拓司
    • Journal Title

      シミュレーション 1

      Pages: 60-65

    • NAID

      130004544028

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Suspension biomechanics of swimming microbes2009

    • Author(s)
      T. Ishikawa
    • Journal Title

      Journal of the Royal Society Interface 6

      Pages: 815-834

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Dancing Volvox: Hydrodynamic bound states of swimming algae2009

    • Author(s)
      K. Drescher, K. Leptos, I. Tuval, T. Ishikawa, T.J. Pedley, R.E. Goldstein
    • Journal Title

      Physical Review Letters 102(cover)

      Pages: 168101-168101

    • NAID

      120003780457

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Red blood cell motions in high-hematocrit blood flowing through a stenosed microchannel2009

    • Author(s)
      H. Fujiwara, T. Ishikawa, R. Lima, N. Matsuki, Y. Imai, H. Kaji, M. Nishizawa, T. Yamaguchi
    • Journal Title

      Journal of Biomechanics 42

      Pages: 838-843

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Suspension biomechanics of swimming microbes2009

    • Author(s)
      石川拓司
    • Journal Title

      Journal of the Royal Society Interface 6

      Pages: 815-834

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Can temporal fluctuation in spatial wall shear stress gradient initiate a cerebral aneurysm? A proposed novel hemodynamic index, the gradient oscillatory number(GON)2009

    • Author(s)
      Y.Shimogonya
    • Journal Title

      Journal of Biomechanics 42

      Pages: 550-554

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 「次世代医療関連産業中核人材育成のための実践的教育システム」の開発と実証研究2009

    • Author(s)
      山野真裕
    • Journal Title

      工学教育 57

      Pages: 13-21

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hemodynamic analysis of micro-circulation in malaria infection2009

    • Author(s)
      H.Kondo
    • Journal Title

      Annals of Biomedical Engineering 37

      Pages: 702-709

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Red blood cell motions in high-hematocrit blood flowing through a stenosed microchannel2009

    • Author(s)
      H.Fujiwara
    • Journal Title

      Journal of Biomechanics 42

      Pages: 838-843

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dancing Volvox : Hydrodynamic bound states of swimming algae2009

    • Author(s)
      K.Drescher
    • Journal Title

      Physical Review Letters 102

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of unique biomedical education programs for engineers : REDEEM and ESTEEM projects2009

    • Author(s)
      N.Matsuki
    • Journal Title

      Advances in Physiology Education 33

      Pages: 91-97

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An internet-based wearable watch-over system for elderly and disabled utilizing EMG and accelerometer2009

    • Author(s)
      M.Kishimoto
    • Journal Title

      Technology and Health Care 17

      Pages: 121-131

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Measurement of individual red blood cell motions under high hematocrit conditions using a confocal micro-PTV system2009

    • Author(s)
      R.Lima
    • Journal Title

      Annals of Biomedical Engineering 37

      Pages: 1546-1559

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Axisymmetric polydimethysiloxane microchannels for in vitro haemodynamic studies2009

    • Author(s)
      R.Lima
    • Journal Title

      Biofabrication 1

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A realistic simulation of saccular cerebral aneurysm formation : focussing on a novel haemodynamic index, the gradient oscillatory number2009

    • Author(s)
      Y.Shimogonya
    • Journal Title

      International Journal of Computational Fluid Dynamics 23

      Pages: 583-593

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a biologically inspired locomotion system for a capsule endoscope2009

    • Author(s)
      D.Hosokawa
    • Journal Title

      International Journal of Medical Robotics and Computer Assisted Surgery 5

      Pages: 471-478

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 準希薄微生物溶液における自己拡散シミュレーション ―せん断流れの影響―2009

    • Author(s)
      石川拓司
    • Journal Title

      シミュレーション 1

      Pages: 60-65

    • NAID

      130004544028

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Simulation of platelet adhesion and aggregation regulated by fibrinogen and von Willebrand factor2008

    • Author(s)
      D.Mori, K.Yano, K.Tsubota, T.Ishikawa, S.Wada, T.Yamaguchi
    • Journal Title

      Thrombosis and Haemostasis 99

      Pages: 108-115

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vitro blood flow in a rectangular PDMS microchannel : experimental observations using a confocal micro-PIV system2008

    • Author(s)
      R.Lima, S.Wada, S.Tanaka, M.Takeda, T.Ishikawa, K.Tsubota, Y.Imai, T.Yamaguchi
    • Journal Title

      Biomedical Microdevices 102

      Pages: 153-167

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Coherent Structures in Monolayers of Swimming Particles2008

    • Author(s)
      T.Ishikawa, T.J.Pedley
    • Journal Title

      Physical Review Letters 100

      Pages: 88103-88103

    • NAID

      120003780367

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A rule-based computational study on the early progression of intracranial aneurysms using fluid-structure interaction : Comparison between straight model and curved model2008

    • Author(s)
      Y.Feng, S.Wada, T.Ishikawa, K.Tsubota, T.Yamaguchi
    • Journal Title

      Journal of Biomechanical Science and Engineering 3

      Pages: 124-137

    • NAID

      130000079479

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Shear-induced fluid-tracer diffusion in a semi-dilute suspension of spheres2008

    • Author(s)
      T.Ishikawa, T.Yamaguchi
    • Journal Title

      Physical Review E 77

      Pages: 41402-41402

    • NAID

      120003780426

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radial dispersion of red blood cells in blood flowing through glass capillaries : Role of Hematocrit andgeometry2008

    • Author(s)
      R.Lima, T.Ishikawa, Y.Imai, M.Takeda, S.Wada, T.Yamaguchi
    • Journal Title

      Journal of Biomechanics 41

      Pages: 2188-2196

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Importance of parent artery geometry in intra-aneurysm hemodynamics studies2008

    • Author(s)
      K.Sato, Y.Imai, T.Ishikawa, N.Matsuki, T.Yamaguchi
    • Journal Title

      Medical Engineering & Physics 30

      Pages: 774-782

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inflow into saccular cerebral aneurysms at arterial bends2008

    • Author(s)
      Y.Imai, K.Sato, T.Ishikawa, T.Yamaguchi
    • Journal Title

      Annals of Biomedical Engineering 36

      Pages: 1489-1495

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low voltage pulses can induce apoptosis2008

    • Author(s)
      N.Matsuki, T.Ishikawa, Y.Imai, T.Yamaguchi
    • Journal Title

      Cancer Letters 269

      Pages: 93-100

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of saccular cerebral aneurysms may require proliferation of the arterial wall (Computational investigation)2008

    • Author(s)
      Y.Shimogonya, T.Ishikawa, Y.Imai, D.Mori, N.Matsuki, T.Yamaguchi
    • Journal Title

      Journal of Biomechanical Science and Engineering 3

      Pages: 431-442

    • NAID

      130000079456

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of coherent structures in concentrated suspensions of swimming model micro-organisms2008

    • Author(s)
      T.Ishikawa, J.T.Locsei, T.J.Pedley
    • Journal Title

      Journal of Fluid Mechanics 615

      Pages: 401-431

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a wearable system module for monitoring physical and mental workloads2008

    • Author(s)
      S.Kim, H.Nakamura, T.Yoshida, M.Kishimoto, Y.Imai, N.Matsuki, T.Ishikawa, T.Yamaguchi
    • Journal Title

      Telemedicine and e-Health 14

      Pages: 939-945

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the red blood cells on the primary thrombus formation2008

    • Author(s)
      D.Mori, K.Yano, K.Tsubota, T.Ishikawa, S.Wada, T.Yamaguchi
    • Journal Title

      Thrombosis Research 123

      Pages: 114-121

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of coherent structures in concentrated suspensions of swimming model micro-organisms2008

    • Author(s)
      T. Ishikawa, J.T. Locsei, T.J. Pedley
    • Journal Title

      Journal of Fluid Mechanics 615

      Pages: 401-431

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Coherent Structures in Monolayers of Swimming Particles2008

    • Author(s)
      T. Ishikawa, T.J. Pedley
    • Journal Title

      Physical Review Letters 100

      Pages: 88103-88103

    • NAID

      120003780367

    • Related Report
      2009 Self-evaluation Report
  • [Journal Article] Simulation of platelet adhesion and aggregation regulated by fibrinogen and von Willebrand factor2008

    • Author(s)
      D. Mori
    • Journal Title

      Thrombosis and Haemostasis 99

      Pages: 108-115

    • Related Report
      2008 Annual Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro blood flow in a rectangular PDMS mitrochannel : experimental observations using a confocal micro-PIV system2008

    • Author(s)
      R. Lima
    • Journal Title

      Biomedical Microdevices 10

      Pages: 153-167

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coherent Structures in Monolayers of Swimming Particles2008

    • Author(s)
      T. Ishikawa
    • Journal Title

      Physical Review Letters 10

      Pages: 88103-88103

    • NAID

      120003780367

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A rule-based computational study on the early progression of intracranial aneurysms using fluidstructure interaction2008

    • Author(s)
      Y. Feng
    • Journal Title

      Journal of Biomechanical Science and Engineering 3

      Pages: 124-137

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Shearinduced fluidtracer diffusion in a semidilute suspension of spheres2008

    • Author(s)
      T. Ishikawa
    • Journal Title

      Physical Review E 77

      Pages: 41402-41402

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radial dispersion of red blood cells in blood flowing through glass capillaries : Role of Hematocrit and geometry2008

    • Author(s)
      R. Lima
    • Journal Title

      Journal of Biomechanics 41

      Pages: 2188-2196

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inflow into saccular cerebral aneurysms at arterial bends2008

    • Author(s)
      Y. Imai
    • Journal Title

      Annals of Biomedical Engineering 36

      Pages: 1489-1495

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of parent artery geometry in intraaneurysm hemodynamics studies2008

    • Author(s)
      K. Sato
    • Journal Title

      Mdeical Engineering & Physics 30

      Pages: 774-782

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low voltage pulses can induce apoptosis2008

    • Author(s)
      N. Matsuki
    • Journal Title

      Cancer Letters 269

      Pages: 93-100

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Formation of saccular cerebral aneurysms may require proliferation of the arterial wall2008

    • Author(s)
      Y. Shimogonya
    • Journal Title

      Journal of Biomechanical Science and Engineering 3

      Pages: 431-442

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of coherent structures in concentrated suspensions of swimming model microorganisms2008

    • Author(s)
      T. Ishikawa
    • Journal Title

      Journal of Fluid Mechanics 615

      Pages: 401-431

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a wearable system module for monitoring physical and mental workloads2008

    • Author(s)
      S. Kim
    • Journal Title

      Telemedicine and e-Health 14

      Pages: 939-945

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the red blood cells on the primary thrombus formation2008

    • Author(s)
      D. Mori
    • Journal Title

      Thrombosis Research 123

      Pages: 114-121

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 東北大学における「医療工学技術者創成のための再教育システム」の実践2008

    • Author(s)
      山野真裕
    • Journal Title

      工学教育 56

      Pages: 125-132

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro blood flow in a rectangular PDMS microchannel: experimental observations using a confocal micro-PIV system2008

    • Author(s)
      R. Lima
    • Journal Title

      Biomedical Microdevices 10

      Pages: 153-167

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of parent artery geometry in intra-aneurysm hemodynamics studies2008

    • Author(s)
      K. Sato
    • Journal Title

      Medical Engineering & Physics (In press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coherent Structures in Monolayers of Swimming Particles2008

    • Author(s)
      T. Ishikawa
    • Journal Title

      Physical Review Letters 100

    • NAID

      120003780367

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical simulation of a low-hematocrit blood flow in a small artery with stenosis2007

    • Author(s)
      T.Ishikawa, N.Kawabata, Y.Imai, K.Tsubota, T.Yamaguchi
    • Journal Title

      Journal of Biomechanical Science and Engineering 2

      Pages: 12-22

    • NAID

      130000079520

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of destruction process of the primary thrombus under the influence of the blood flow2007

    • Author(s)
      K.Yano, D.Mori, K.Tsubota, T.Ishikawa, S.Wada, T.Yamaguchi
    • Journal Title

      Journal of Biomechanical Science and Engineering 2

      Pages: 34-44

    • NAID

      130000079516

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the wall motion on arterial wall shear stress2007

    • Author(s)
      T.Fukui, K.H.Parker, Y.Imai, K.Tsubota, T.Ishikawa, S.Wada, T.Yamaguchi
    • Journal Title

      Journal of Biomechanical Science and Engineering 2

      Pages: 58-68

    • NAID

      130000079513

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hydrodynamic interaction between two swimming bacteria2007

    • Author(s)
      T.Ishikawa, G.Sekiya, Y.Imai, T.Yamaguchi
    • Journal Title

      Biophysical Journal 93

      Pages: 2217-2225

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The rheology of a semi-dilute suspension of swimming model micro-organisms2007

    • Author(s)
      T.Ishikawa, T.J.Pedley
    • Journal Title

      Journal of Fluid Mechanics 588

      Pages: 399-435

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of swimming model micro-organisms in a semi-dilute suspension2007

    • Author(s)
      T.Ishikawa, T.J.Pedley
    • Journal Title

      Journal of Fluid Mechanics 588

      Pages: 437-462

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Orientational relaxation time of bottom-heavy squirmers in a semi-dilute suspension2007

    • Author(s)
      T.Ishikawa, T.J.Pedley, T.Yamaguchi
    • Journal Title

      Journal of Theoretical Biology 249

      Pages: 296-306

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hydrodynamic interaction between two swimming bacteria2007

    • Author(s)
      T. Ishikawa
    • Journal Title

      Biophysical Journal 93

      Pages: 2217-2225

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The rheology of a semi-dilute suspension of swimming model micro-organisms2007

    • Author(s)
      T. Ishikawa
    • Journal Title

      Journal of Fluid Mechanics 588

      Pages: 399-435

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion of swimming model micro-organisms in a semi-dilute suspension2007

    • Author(s)
      T.Ishikawa
    • Journal Title

      Journal of Fluid Mechanics 588

      Pages: 437-462

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Orientational relaxation time of bottom-heavy squirmers in a semi-dilute suspension2007

    • Author(s)
      T. Ishikawa
    • Journal Title

      Journal of Theoretical Biology 249

      Pages: 296-306

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a wearable surveillance system using gait analysis2007

    • Author(s)
      T. Yoshida
    • Journal Title

      Telemedicine and e-Health 13

      Pages: 703-714

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Impact of membrane modeling on the deformation analysis of a capsule2009

    • Author(s)
      T.Omori
    • Organizer
      3rd East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore
    • Year and Date
      2009-12-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] Patient□specific morphological and hemodynamic analysis of pulmonary artery in the case of severe deformations of the lung2009

    • Author(s)
      J-J.Christophe
    • Organizer
      3rd East Asian Pacific Student Workshop on Nano-Biomedical Engineering
    • Place of Presentation
      National University of Singapore, Singapore
    • Year and Date
      2009-12-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] Shear-induced fluid-tracer diffusion in a semi-dilute suspension of spheres2009

    • Author(s)
      T.Ishikawa
    • Organizer
      62nd Annual Meeting of the APS Division of Fluid Dynamics
    • Place of Presentation
      Minnesota, USA
    • Year and Date
      2009-11-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Shear-induced fluid-tracer diffusion in a semi-dilute suspension of spheres, Bulletin of the American Physical Society2009

    • Author(s)
      T.Ishikawa, T.Yamaguchi
    • Organizer
      DFD 2009,Vol.54, No.19, p.293
    • Place of Presentation
      Minneapolis,米国
    • Year and Date
      2009-11-22
    • Related Report
      2009 Final Research Report
  • [Presentation] Shear-induced fluid-tracer diffusion in a semi-dilute suspension of spheres2009

    • Author(s)
      T. Ishikawa, T. Yamaguchi
    • Organizer
      Bulletin of the American Physical Society, DFD 2009
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2009-11-22
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Fluid flow analysis on the surface of tracheal ciliary cells2009

    • Author(s)
      H.Ueno
    • Organizer
      International Workshop Dynein 2009
    • Place of Presentation
      Kobe
    • Year and Date
      2009-11-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Diffusion in concentrated suspensions of biological cells2009

    • Author(s)
      T. Ishikawa
    • Organizer
      Computational Vision and Medical Image Processing - VipIMAGE 2009
    • Place of Presentation
      Porto, Portugal(CRC press)
    • Year and Date
      2009-10-17
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Diffusion in concentrated suspensions of biological cells, Computational Vision and Medical Image Processing - VipIMAGE 20092009

    • Author(s)
      T.Ishikawa
    • Organizer
      CRC press, pp.327-330
    • Place of Presentation
      Port,ポルトガル
    • Year and Date
      2009-10-15
    • Related Report
      2009 Final Research Report
  • [Presentation] Patient-specific blood flow analysis of pulmonary artery affected by severe deformations of the lung2009

    • Author(s)
      J-J.Christophe
    • Organizer
      VIPIMAGE2009
    • Place of Presentation
      Port, Portugal
    • Year and Date
      2009-10-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Motions of particles and red blood cells in a bifurcation : comparison between experiments and numerical simulations2009

    • Author(s)
      M.Lagoela
    • Organizer
      VIPIMAGE2009
    • Place of Presentation
      Port, Portugal
    • Year and Date
      2009-10-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Determination of the cell-free layer in circular PDMS microchannels2009

    • Author(s)
      T.Cerdeira
    • Organizer
      VIPIMAGE2009
    • Place of Presentation
      Port, Portugal
    • Year and Date
      2009-10-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] Diffusion in concentrated suspensions of biological cells2009

    • Author(s)
      T.Ishikawa
    • Organizer
      VipIMAGE2009-I ECCOMAS Them.Conf.Comp.Vis.Med.Image Proc.
    • Place of Presentation
      Port, Portugal
    • Year and Date
      2009-10-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] Simulation of rosette formation and destruction of malaria infected red blood cells2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      Bioengineering 09
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Pulmonary airflow simulation of inspiration and expiration using a patient-specific model2009

    • Author(s)
      T.Miki
    • Organizer
      Bioengineering 09
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] On the sensitivity of a hemodynamic index for cerebral aneurysm initiation, the GON, to flow input waveform2009

    • Author(s)
      Y.Shimogonya
    • Organizer
      Bioengineering 09
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Simulation of microcirculatory disorder by malaria infection using a particle method2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      ICCB 2009, IV International Congress on Computational Bioengineering
    • Place of Presentation
      Bertinoro, Italy
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Particle method simulation of red blood cells infected by malaria2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      11th International Congress of the IUPESM, Medical Physics and Biomedical Engineering World Congress 2009
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mixing of red blood cells in high hematocrit blood flow in micro-channels2009

    • Author(s)
      T. Ishikawa, H. Fujiwara, R. Lima, N. Matsuki, Y. Imai, T. Yamaguchi
    • Organizer
      Proc. 3rd Switzerland-Japan Workshop on Biomechanics 2009
    • Place of Presentation
      Engelberg, Switzerland
    • Year and Date
      2009-09-04
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Mixing of red blood cells in high hematocrit blood flow in micro-channels2009

    • Author(s)
      T.Ishikawa
    • Organizer
      3^<rd> Switzerland-Japan Workshop on Biomechanics 2009
    • Place of Presentation
      Engelberg, Switzerland
    • Year and Date
      2009-09-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mixing of red blood cells in high hematocrit blood flow in micro-channels2009

    • Author(s)
      T.Ishikawa, H.Fujiwara, R.Lima, N.Matsuki, Y.Imai, T.Yamaguchi
    • Organizer
      Proc.3rd Switzerland-Japan Workshop on Biomechanics 2009, p.47
    • Place of Presentation
      Engelberg,スイス
    • Year and Date
      2009-09-02
    • Related Report
      2009 Final Research Report
  • [Presentation] Fluid Particle Diffusion in a Semi-dilute Suspension of Model Micro-organisms2009

    • Author(s)
      T. Ishikawa, J.T. Locsei, T.J. Pedley
    • Organizer
      The 4th International Symposium on Aero Aqua Bio-Mechanisms 2009
    • Place of Presentation
      上海, 中国(CD-ROM S01)
    • Year and Date
      2009-08-30
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Fluid particle diffusion in a semi-dilute suspension of model micro-organisms2009

    • Author(s)
      T.Ishikawa
    • Organizer
      The Fourth International Symposium on Aero Aqua Bio-Mechanisms
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2009-08-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Suspension biomechanics of swimming microbes2009

    • Author(s)
      T.Ishikawa
    • Organizer
      Workshop on Active Matter -Physics of Biokinetics-
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-07-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] A particle based modeling and analysis of malaria infected red blood cell in microcirculation2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      10th U.S.National Congress on Computational Mechanics
    • Place of Presentation
      Ohio, USA
    • Year and Date
      2009-07-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Computational biomechanics of malaria and arterial diseases2009

    • Author(s)
      T. Ishikawa
    • Organizer
      37th Int. Cong. Physiol. Sci. (IUPS2009)
    • Place of Presentation
      京都, 日本
    • Year and Date
      2009-07-06
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] A numerical model of adhesion property of malaria infected red blood cells in micro scale blood flows2009

    • Author(s)
      Y.Imai
    • Organizer
      2009 Summer Bioengineering Conference
    • Place of Presentation
      California, USA
    • Year and Date
      2009-06-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rheology of cancer cells with different metastatic properties2009

    • Author(s)
      T.Yoshimoto
    • Organizer
      2009 Summer Bioengineering Conference
    • Place of Presentation
      California, USA
    • Year and Date
      2009-06-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Individual motions of red blood cells in high-hematocrit blood flowing in a microchannel with complex geometries2009

    • Author(s)
      T.Ishikawa
    • Organizer
      2009 Summer Bioengineering Conference
    • Place of Presentation
      California, USA
    • Year and Date
      2009-06-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Dynein pulls microtubules without rotating its stalk2009

    • Author(s)
      H.Ueno
    • Organizer
      2009 Summer Bioengineering Conference
    • Place of Presentation
      California, USA
    • Year and Date
      2009-06-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Microvascular disorders induced by malaria infected red blood cells : a computational mechanical study using the biological particle method2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      Biomed 2009
    • Place of Presentation
      Crete, Greece
    • Year and Date
      2009-05-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] Motion of individual red blood cells in a concentrated suspension flowing through micro-channels2009

    • Author(s)
      T.Ishikawa
    • Organizer
      4th Asian Pacific Conference on Biomechanics
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Numerical simulation of inpiratory and expiratory pulmonary airflow using a patient-specific model2009

    • Author(s)
      T.Miki
    • Organizer
      10th International Symposium of Tohoku University Global COE Program, Global Nano-Biomedical Engineering Education and Research Network Centre, Nano-Biomedical Engineering in the East Asian-Pacific Rim Region, Jointly Organised with Fourth Asian Pacific Conference on Biomechanics
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Computational biomechanics of the human cardiovascular system-an overview2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      10th International Symposium of Tohoku University Global COE Program, Global Nano-Biomedical Engineering Education and Research Network Centre, Nano-Biomedical Engineering in the East Asian-Pacific Rim Region, Jointly Organised with Fourth Asian Pacific Conference on Biomechanics
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of the memberane bending stiffeness on the deformation of a red blood cell2009

    • Author(s)
      T.Omori
    • Organizer
      10th International Symposium of Tohoku University Global COE Program, Global Nano-Biomedical Engineering Education and Research Network Centre, Nano-Biomedical Engineering in the East Asian-Pacific Rim Region, Jointly Organised with Fourth Asian Pacific Conference on Biomechanics
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] A micro scale blood flow model to study pathology of malaria2009

    • Author(s)
      Y.Imai
    • Organizer
      4th Asian Pacific Conference on Biomechanics
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Computational biomechanics for investigating various diseases over micro to macro scales2009

    • Author(s)
      T.Yamaguchi
    • Organizer
      ICCES'09(International Conference on Computational & Experimental Engineering and Sciences)
    • Place of Presentation
      Phuket, Thailand
    • Year and Date
      2009-04-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Motion of individual cells in high hematocrit blood flow in micro-channels2009

    • Author(s)
      T.Ishikawa
    • Organizer
      Int.Conf.Comp.Exp.Eng.Sci.(ICCES'09)
    • Place of Presentation
      Phuket, Thailand
    • Year and Date
      2009-04-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] A numerical model to study hemodynamics arising from malaria infection2009

    • Author(s)
      Y.Imai
    • Organizer
      ICCES'09(International Conference on Computational & Experimental Engineering and Sciences)
    • Place of Presentation
      Phuket, Thailand
    • Year and Date
      2009-04-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Patient-specific pulmonary airflow simulation using cartestian adaptive mesh refinement method2009

    • Author(s)
      T.Miki
    • Organizer
      15th International Conference on Finite Elements in Flow Problems(FEF09)
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-04-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Modeling of the membrane bending rigidity for calculating red blood cell deformation2009

    • Author(s)
      T.Omori
    • Organizer
      15th International Conference on Finite Elements in Flow Problems(FEF09)
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-04-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Biomechanics of a suspension of microorganisms2008

    • Author(s)
      T. Ishikawa
    • Organizer
      Proc. 13^<th> Int Conf. Biomed. Eng
    • Place of Presentation
      シンガポール
    • Year and Date
      2008-12-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Numerical analysis of a stable waltzing pair of Volvox2008

    • Author(s)
      T. Ishikawa
    • Organizer
      Bulletin of the American Physical Society, DFD
    • Place of Presentation
      San Antonio, USA
    • Year and Date
      2008-11-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] Mixing of red blood cells in a microchannel flow under high hematocrit conditions2008

    • Author(s)
      T. Ishikawa
    • Organizer
      Bioengineering 08 Book of Abstracts
    • Place of Presentation
      London, UK
    • Year and Date
      2008-09-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] StokesianDynamics Simulation of a Suspension of Swimming Micro-Organisms2008

    • Author(s)
      T. Ishikawa
    • Organizer
      IACM/ECCOMAS Congress 2008
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2008-07-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Modeling of malaria-infected red blood cell mechanics using a particle method2007

    • Author(s)
      H. Kondo
    • Organizer
      APCOM'07 in conjunction with EPMESC XI
    • Place of Presentation
      京都
    • Year and Date
      2007-12-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] Numerical simulation of cerebral aneurysm growth based on a hemodynamic hypothesis2007

    • Author(s)
      Y. Shimogonya
    • Organizer
      APCOM'07 in conjunction with EPMESC XI
    • Place of Presentation
      京都
    • Year and Date
      2007-12-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] Suspensions of swimming micro-organisms2007

    • Author(s)
      T. Ishikawa
    • Organizer
      APCOM'07 in conjunction with EPMESC XI
    • Place of Presentation
      京都
    • Year and Date
      2007-12-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] An AMR Method based on the IDO scheme for patient-specific pulmonary airflow simulation2007

    • Author(s)
      Y. Imai
    • Organizer
      APCOM'07 in conjunction with EPMESC XI
    • Place of Presentation
      京都
    • Year and Date
      2007-12-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] The role of near field interactions in the collective behaviour of model swimming micro-organisms2007

    • Author(s)
      T. Locsei
    • Organizer
      Bulletin of the American Physical Society
    • Place of Presentation
      ソルトレークシティ(米国)
    • Year and Date
      2007-11-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] The hydrodynamics of interactions between two swimming bacteria2007

    • Author(s)
      T. Ishikawa
    • Organizer
      Bulletin of the American Physical Society
    • Place of Presentation
      ソルトレークシティ(米国)
    • Year and Date
      2007-11-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] Relaxation Time of Bottom-Heavy Squirmers in a Semi-Dilute Suspension2007

    • Author(s)
      T. Ishikawa
    • Organizer
      Proc. 3rd Asian Pacific Conf. Biomech
    • Place of Presentation
      東京
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Numerical Simulation of Malaria-Infected, Blood Flow using a Particle Method2007

    • Author(s)
      H. Kondo
    • Organizer
      Proc. 3rd Asian Pacific Conf. Biomech
    • Place of Presentation
      東京
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Computational Study of Platelet Thrombus Formation in a Blood Flow2007

    • Author(s)
      D. Mori
    • Organizer
      Proc. 3rd Asian Pacific Conf. Biomech
    • Place of Presentation
      東京
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Book] Modelling in Medicine and Biology VIII(Microvascular disorders induced by malaria infected red blood cells : a computational mechanical study using the biological particle method)2009

    • Author(s)
      T.Yamaguchi, H.Kondo, Y.Imai, T.Ishikawa
    • Publisher
      WIT press
    • Related Report
      2009 Final Research Report
  • [Book] Advances in Computational Vision and Medical Image Processing, Methods and Applications Series : Computational Methods in Applied Sciences, 13(Microscale Flow Dynamics of Red Blood Cells in Microchannels : An Experimental and Numerical Analysis)2008

    • Author(s)
      R.Lima, M.Nakamura, T.Omori, T.Ishikawa, S.Wada, T.Yamaguchi
    • Publisher
      Springer
    • Related Report
      2009 Final Research Report
  • [Book] Bio-mechanisms of Swimming and Flying(Properties of a Semi-dilute Suspension of Swimming Micro-organisms)2007

    • Author(s)
      T.Ishikawa, T.Yamaguchi, T.J.Pedley
    • Publisher
      Springer-Verlag
    • Related Report
      2009 Final Research Report
  • [Book] Bio-mechanisms of Swimming and Flying(Properties of a Semi-dilute Suspension of Swimming Micro-organisms)2007

    • Author(s)
      T. Ishikawa, T. Yamaguchi, T.J. Pedley
    • Publisher
      Springer-Verlag
    • Related Report
      2009 Self-evaluation Report
  • [Book] Advances in Computational Vision and Medical Image Processing, Methods and Applications Series: Computational Methods in Applied Sciences, 13(Microscale Flow Dynamics of Red Blood Cells in Microchannels: An Experimental and Numerical Analysis)

    • Author(s)
      R. Lima, M. Nakamura, T. Omori, T. Ishikawa, S. Wada, T. Yamaguchi
    • Publisher
      Springer
    • Related Report
      2009 Self-evaluation Report
  • [Remarks] ホームページ等

    • Related Report
      2009 Final Research Report
  • [Remarks] 研究成果のホームページ

    • URL

      http://db.tohoku.ac.jp/whois/detail/5e15d83900e65b755d2af8dd6a078164.html

    • Related Report
      2009 Final Research Report
  • [Remarks] 研究成果のホームページ:

    • URL

      http://db.tohoku.ac.jp/whois/detail/5e15d83900e65b755d2af8dd6a078164.html

    • Related Report
      2009 Self-evaluation Report
  • [Remarks]

    • URL

      http://db.tohoku.ac.jp/whois/detail/5e15d83900e65b755d2af8dd6a078164.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://db.tohoku.ac.jp/whois/detail/5e15d83900e65b755d2af8dd6a078164.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://db.tohoku.ac.jp/whois/detail/5e15d83900e65b755d2af8dd6a078164.html

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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