Budget Amount *help |
¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2007: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
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Research Abstract |
The author investigated development of synthetic methods based on catalytic cascade of atom-economical reactions such as C-H bond activation and multi-component reactions. Consequently, several methods for construction of fused heterocycles such as indoles, isoquinolines, isoindoles, carbazoles, and quinazolines have been developed. Furthermore, total syntheses of ergot alkaloids and jaspine B, as well as efficient synthesis of trifluoromethylalkene dipeptide isosteres have been achieved. These results provide a preliminary model for efficient organic synthesis.
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