Absorbed dose measurement using implantable dosimeter during radiotherapy and prevention of radiation damage

• Project/Area Number: 19689025
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Hokkaido University
• Principal Investigator: ISHIKAWA Masayori Hokkaido University, 大学院・医学研究科, 准教授 (80314772)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000); Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2008: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000); Fiscal Year 2007: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
• Keywords: 放射線治療学 / リアルタイム線量評価 / in vivo dosimetry / 体内線量測定 / 密封小線源治療 / 放射線障害予防 / リアルタイム線量測定 / 線量計開発 / 超小型線量計

Research Abstract

We published a paper regarding basic concept of SOF dosimeter (Scintillator with optical Fiber Dosimeter) as a function of dosimeter. SOF dosimeter measurements were performed for 11 patients who had a high dose rate brachytherapy undergoing to prostate cancer. Measurements were performed at the highest dose point inside the urethra predicted by treatment planning software, the dose given during the treatment was confirmed by real-time monitoring. To adapt high energy X ray or gamma ray measurement, dichroic mirror type SOF dosimeter was developed. We optimized the threshold wavelength of the dichroic mirror. Moreover, we developed 192 channel type SOF dosimeter system.

Research Products

• [Journal Article] A feasibility study of novel plastic scintillation dosimetry with pulse counting mode (2009)
  • Author(s): M.Ishikawa, G.Bengua, K.Sutherland, J.Hiratsuka, N.Katoh, S.Shimizu, H.Aoyama, K.Fujita, R.Yamazaki, K.Horita, H.Shirato
  • Journal Title: Physics in Medicine and Biology Vol54 Pages: 2079-2092
  • Peer Reviewed
• [Journal Article] A feasibility study of novel plastic scintillation dosimetry with pulse counting mode (2009)
  • Author(s): M.Ishikawa, G.Bengua, K.Suther1, J.Hiratsuka, N.Katoh, S.Shimizu, H.Aoyama, K.Fujita, R.Yamazaki, K.Horita, H.Shirato
  • Journal Title: Physics in Medicine and Biology 54 Pages: 2079-2092
  • Peer Reviewed
• [Journal Article] A feasibility study of novel plastic scintillation dosimetry with pulse counting mode (2009)
  • Author(s): M. Ishikawa, G. Bengua, K. Sutherland, J. Hiratsuka, N. Katoh, S. Shimizu, H. Aoyama, K. Fujita, R. Yamazaki, K. Horita and H. Shirato
  • Journal Title: Physics in Medicine and Biology 54 Pages: 2079-2092
  • Peer Reviewed
• [Presentation] 光ファイバ線量計を用いた高エネルギーγ線線量測定におけるチェレンコフ光除去方法の検討 (2010)
  • Author(s): 太田真緒、石川正純, ほか
  • Organizer: 日本医学物理学会第99回学術大会
  • Place of Presentation: パシフィコ横浜(横浜市)
  • Year and Date: 2010-04-10
• [Presentation] SOF線量計によるIr-192高線量率密封小線源治療時のin-vivoリアルタイム線量測定 (2008)
  • Author(s): 石川正純、平塚純一、長瀬尚巳、Gerard Bengua、Kenneth Sutherland、加藤徳雄、清水伸一、鬼丸力也、青山英史、白土博樹
  • Organizer: 日本放射線腫瘍学会第21回学術大会
  • Place of Presentation: 札幌
• [Presentation] SOF線量計による前立腺密封小線源治療時のリアルタイム線量測定 (2008)
  • Author(s): 石川正純、平塚純一、長瀬尚巳、大坂康博、Gerard Bengua、白土博樹
  • Organizer: 第95回日本医学物理学会学術大会
  • Place of Presentation: 横浜
• [Presentation] SOF線量計による前立腺密封小線源治療時のリアルタイム線量測定(大会長賞受賞) (2008)
  • Author(s): 石川正純、平塚純一、長瀬尚巳、大坂康博、Gerard Bengua、白土博樹
  • Organizer: 第95回日本医学物理学会学術大会
  • Place of Presentation: 横浜
• [Presentation] Wide Range and High Spatial Resolution in-vivo Dosimetory Using Ultraminiature Plastic Scintillator with Pulse Counting Method (2007)
  • Author(s): M.Ishikawa, Y.Osaka, J.Hiratsuka, G.Bengua, H.Shirato
  • Organizer: 49th Annual meeting of American Society of Therapeutic Radiology and Oncology
  • Place of Presentation: Los Angeles
• [Presentation] SOF線量計を用いた密封小線源治療用Ir-192線源の強度分布測定 (2007)
  • Author(s): 石川正純、笈田将皇、加藤徳雄、藤野賢治、大坂康博、白土博樹
  • Organizer: 第93回日本医学物理学会
  • Place of Presentation: 横浜
• [Patent(Industrial Property Rights)] Radiation dosimeter and radiation dose computing program (2009)
  • Inventor(s): Masayori Ishikawa
  • Industrial Property Rights Holder: National University Corporation Hokkaido University
  • Filing Date: 2009-04-16
• [Patent(Industrial Property Rights)] Radiation dosimeter and radiation dose computing program (2009)
  • Inventor(s): Masayori Ishikawa
  • Industrial Property Rights Holder: National University Corporation Hokkaido University
  • Filing Date: 2009-03-26
• [Patent(Industrial Property Rights)] 放射線線量計および放射線線量計算プログラム (2009)
  • Inventor(s): 石川正純
  • Industrial Property Rights Holder: 国立大学法人北海道大
  • Filing Date: 2009-01-22
• [Patent(Industrial Property Rights)] 放射線線量計および放射線線量計算プログラム (2009)
  • Inventor(s): 石川正純
  • Industrial Property Rights Holder: 北海道大学
  • Filing Date: 2009-03-23
• [Patent(Industrial Property Rights)] 放射線線量計および放射線線量計算プログラム (2007)
  • Inventor(s): 石川正純
  • Industrial Property Rights Holder: 北海道大学
  • Filing Date: 2007-09-26
  • Overseas