Development of a passive-active artificialmyocardium reconcilingthe physiological demands with hemodynamic changes
| Project/Area Number |
19689029
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
SHIRAISHI Yasuyuki Tohoku University, 加齢医学研究所, 准教授 (00329137)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMBE Tomoyuki 東北大学, 加齢医学研究所, 教授 (70241578)
SAIJO Yoshifumi 東北大学, 医工学研究科, 教授 (00292277)
UMEZU Mitsuo 早稲田大学, TWIns, 教授 (90132927)
FUJIMOTO Tetsuo 早稲田大学, 理工学術院, 教授 (50267473)
BABA Atsushi 芝浦工業大学, 生命科学科, 教授 (50392444)
TABAYASHI Koichi 東北大学, 医学系研究科, 教授 (90142942)
HOMMA Dai トキ・コーポレーション, バイオメタル事業部, 取締役開発部長
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2007: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
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| Keywords | 心不全 / 循環補助 / 人工心筋 / 適合制御 / 形状記憶合金線維 |
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| Research Abstract |
We developed a sophisticated artificial myocardium which consisted of shape memory alloy fibre units. We applied the PID method for the control of myocardial assist, and examined the dynamic performance as well as hemodynamic changes in goats. It was anticipated that the passive-active artificial myocardium control could be achieved which was reconciling the physiological demands with pathophysiological diagnosis by using our new methodology.
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Report
(4 results)
Research Products
(125 results)
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[Journal Article] Macrophage colony-stimulating factor improves cardiac function after ischemic injury by inducing vascular endothelial growth factor production and survival of cardiomyocytes2007
Author(s)
Okazaki T, Ebihara S, Asada M, Yamanda S, Saijo Y, Shiraishi Y, Ebihara T, Niu K, Mei H, Arai H, Yambe T
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Journal Title
Am J Pathol 171(4)
Pages: 1093-1103
Related Report
Peer Reviewed
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