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Analysis of Molecular Mechanism of Female Reproductive Organ Tissue Stem Cell Systems for clinical application

Research Project

Project/Area Number 19689034
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Obstetrics and gynecology
Research InstitutionKeio University

Principal Investigator

KAJITANI Takashi  Keio University, 医学部, 助教 (60407111)

Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥27,430,000 (Direct Cost: ¥21,100,000、Indirect Cost: ¥6,330,000)
Fiscal Year 2009: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2007: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Keywords再生医学 / 幹細胞学 / 子宮内膜 / 子宮筋 / 幹細胞 / 遺伝子クローニング
Research Abstract

In this project, we have investigated the molecular mechanisms of the physiological function of the endometrial- and myometrial tissue stem cells, by profiling the specific gene expression pattern of the putative stem cells, and by analyzing each gene's function. The results of this project may solve the some problems for the clinical usage of the stem cells.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (80 results)

All 2010 2009 2008 2007 Other

All Journal Article (30 results) (of which Peer Reviewed: 29 results) Presentation (48 results) Remarks (2 results)

  • [Journal Article] Human uterine stem/progenitor cells: their possible role in uterine physiology.2010

    • Author(s)
      Maruyama T, Masuda H, Ono M, Kajitani T, Yoshimura Y
    • Journal Title

      Reproduction (in press.)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stem cell-like properties of the endometrial side population: implication in endometrial regeneration.2010

    • Author(s)
      Masuda H, Matsuzaki Y, Hiratsu E, Ono M, Nagashima T, Kajitani T, Arase T, Oda H, Uchida H, Asada H, Ito M, Yoshimura Y, Maruyama T, Okano H
    • Journal Title

      PLoS One 5(4)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The UDP-glucose receptor P2RY14 triggers innate mucosal immunity in the female reproductive tract by inducing IL-8.2009

    • Author(s)
      Arase T, Uchida H, Kajitani T, Ono M, Tamaki K, Oda H, Nishikawa S, Kagami M, Nagashima T, Masuda H, Asada H, Yoshimura Y, Maruyama T
    • Journal Title

      J Immunol. 182(11)

      Pages: 7074-7084

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Glycodelin blocks progression to S phase and inhibits cell growth: a possible progesterone-induced regulator for endometrial epithelial cell growth.2008

    • Author(s)
      Ohta K, Maruyama T, Uchida H, Ono M, Nagashima T, Arase T, Kajitani T, Oda H, Morita M, Yoshimura Y
    • Journal Title

      Mol Hum Reprod. 14(1)

      Pages: 17-22

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cyp11b1 is induced in the murine gonad by luteinizing hormone/ human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen; conservation and evolution of androgen metabolic pathway.2008

    • Author(s)
      Yazawa T, Uesaka M, Inaoka Y, Mizutani T, Sekiguchi T, Kajitani T, Kitano T, Umezawa A, Miyamoto K
    • Journal Title

      Endocrinology. 149(4)

      Pages: 1786-1792

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activation of SRC kinase and phosphorylation of STAT5 are required for decidual transformation of human endometrial stromal cells.2008

    • Author(s)
      Nagashima T, Maruyama T, Uchida H, Kajitani T, Arase T, Ono M, Oda H, Kagami M, Masuda H, Nishikawa S, Asada H, Yoshimura Y
    • Journal Title

      Endocrinology. 149(3)

      Pages: 1227-1234

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of serum FSH bioactivity in a patient with an FSH-secreting pituitary microadenoma and multicystic ovaries: A Case Report.2008

    • Author(s)
      Kajitani T, Liu S, Maruyama T, Uchida H, Sakurai R, Masuda H, Nagashima T, Ono M, Arase T, Yoshimura Y
    • Journal Title

      Hum Reprod. 23(2)

      Pages: 435-439

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜症・腺筋症由来疼痛に関連する遺伝子の発現解析.2008

    • Author(s)
      梶谷宇, 丸山哲夫, 浅田弘法, 小野政徳, 荒瀬透, 小田英之, 西川明花, 内田浩, 吉村泰典
    • Journal Title

      エンドメトリオーシス研会誌 29

      Pages: 91-93

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 宮内膜症の病因に関する基礎研究子宮内膜症関連遺伝子同定のための新しいアプローチ.2008

    • Author(s)
      丸山哲夫, 梶谷宇, 小田英之, 西川明花, 荒瀬透, 内田浩, 浅田弘法, 吉村泰典
    • Journal Title

      エンドメトリオーシス研会誌 29

      Pages: 42-42

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ヒト子宮内膜様幹細胞の同定・分離とその幹細胞特性の機能解析.2008

    • Author(s)
      升田博隆, 丸山哲夫, 小野政徳, 長島隆, 梶谷宇, 内田浩, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Journal Title

      日本内分泌学会雑誌 84(2)

      Pages: 626-627

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 妊娠子宮における子宮筋Side Population細胞の役割.2008

    • Author(s)
      小野政徳, 丸山哲夫, 梶谷宇, 内田浩, 荒瀬透, 各務真紀, 小田英之, 西川明花, 升田博隆, 長島隆, 太田邦明, 伊藤守, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Journal Title

      日本生殖内分泌学会雑誌 13

      Pages: 25-29

    • NAID

      10021262312

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 異所性子宮内膜症.2008

    • Author(s)
      浅田弘法, 古谷正敬, 西尾浩, 升田博隆, 内田浩, 丸山哲夫, 梶谷宇, 木挽貢慈, 吉村泰典
    • Journal Title

      産婦人科治療 96(3)

      Pages: 241-247

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜脱落膜化の機序の解明-チロシンキナーゼSRCの役割と意義-2008

    • Author(s)
      丸山哲夫, 長島隆, 梶谷宇, 内田浩, 吉村泰典
    • Journal Title

      産婦人科の実際 57(2)

      Pages: 193-198

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of serum FSH bioactivity in a patient with an FSH-secreting pituitary microadenoma and multicystic ovaries : A case report2008

    • Author(s)
      Kajitani T, Liu S, Maruyam a T, Uchida H, Sakurai R, Masuda H, Nagashima T, Ono M, Arase T, Yoshimura Y
    • Journal Title

      Human reproduction 23

      Pages: 435-439

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation of SRC kinase and phosphorylation of signal transducer and activator of transcription-5 are required for decidual transformation of human endometrial stromal cells.2008

    • Author(s)
      Nagashima T, Maruyama T, Uchida H, Kajitani T, Arase T, Ono M, Oda H, Kagami M, Masuda H, Nishikawa S, Asada H, Yoshimura Y
    • Journal Title

      Endocrinology 149

      Pages: 1227-1234

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Glycodelin blocks progression to S phase and inhibits cell growth : a possible progesterone-induced regulator for endometrial epithelial cell growth2008

    • Author(s)
      Ohta K, Maruyama T, Uchida H, Ono M, Nagashima T, Arase T, Kajitani T, Oda H, Morita M, Yoshimura Y
    • Journal Title

      Molecular human reproduction 14

      Pages: 17-22

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyp11b1 is induced in the murine gonad by luteinizing horm one/ human chorionic gonadotropin and involved in the produc tion of 11-ketotestosterone, a major fish androgen : conservation and evolution of the androgen metabolic pathway2008

    • Author(s)
      Yazawa T, Uesaka M, Inaoka Y, Mizutani T, Sekiguchi T, Kajitani T, Kitano T, Umezawa A. Mivamoto K
    • Journal Title

      Endocrinology 149

      Pages: 1786-1792

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜症の病因に関する基礎研究子宮内膜症関連遺伝子同定のための新しいアプローチ2008

    • Author(s)
      丸山哲夫, 梶谷宇, 小田英之, 西川明花, 荒瀬透, 内田浩, 浅田弘法, 吉村泰典
    • Journal Title

      エンドメトリオージス研究会会誌 29

      Pages: 42-42

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【子宮内膜の機能と生殖医療その最前線】子宮内膜脱落膜化の機序の解明チロシンキナーゼSRCの役割と意義2008

    • Author(s)
      丸山哲夫, 長島隆, 梶谷宇, 内田浩, 吉村泰典
    • Journal Title

      産婦人科の実際 57

      Pages: 193-198

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ヒト子宮内膜幹様細胞の同定. 分離とその幹細胞特性の機能解析2008

    • Author(s)
      升田博隆, 丸山哲夫, 小野政徳, 長島隆, 梶谷宇, 内田浩, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Journal Title

      日本内分泌学会雑誌 84

      Pages: 626-627

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 妊娠子宮における子宮筋Side Population細胞の役割2008

    • Author(s)
      小野政徳, 丸山哲夫, 梶谷宇, 内田浩, 荒瀬透, 各務真紀, 小田英之, 西川明花, 升田博隆, 長島隆, 太田邦明, 伊藤守, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Journal Title

      日本生殖内分泌学会雑誌 13

      Pages: 25-29

    • NAID

      10021262312

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜症・腺筋症由来疼痛に関連する遺伝子の発現解析2008

    • Author(s)
      梶谷宇, 丸山哲夫, 浅田弘法, 小野政徳, 荒瀬透, 小田英之, 西川明花, 内田浩, 吉村泰典
    • Journal Title

      エンドメトリオージス研究会会誌 29

      Pages: 91-93

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【子宮内膜症の診療】異所性子宮内膜症2008

    • Author(s)
      浅田弘法, 古谷正敬, 西尾浩, 升田博隆, 内田浩, 丸山哲夫, 梶谷宇, 木挽貢慈, 吉村泰典
    • Journal Title

      産婦人科治療 96

      Pages: 241-247

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells.2007

    • Author(s)
      Ono M, Maruyama T, Masuda H, Kajitani T, Nagashima T, Arase T, Ito M, Ohta K, Uchida H, Asada H, Yoshimura Y, Okano H, Matsuzaki Y
    • Journal Title

      Proc Natl Acad Sci USA. 104(47)

      Pages: 18700-18705

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histone deacetylase inhibitor-induced glycodelin enhances the initial step of implantation.2007

    • Author(s)
      Uchida H, Maruyama T, Ohta K, Ono M, Arase T, Kagami M, Oda H, Kajitani T, Asada H, Yoshimura Y
    • Journal Title

      Hum Reprod. 22(10)

      Pages: 2615-2622

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis.2007

    • Author(s)
      Nagashima T, Maruyama T, Furuya M, Kajitani T, Uchida H, Masuda H, Ono M, Arase T, Ozato K, Yoshimura Y
    • Journal Title

      Mol Hum Reprod. 13(3)

      Pages: 1-8

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histone deacetylase inhibitors stimulate cell migration in human endometrial adenocarcinoma cells through up-regulation of glycodelin.2007

    • Author(s)
      Uchida H, Maruyama T, Ono M, Ohta K, Kajitani T, Masuda H, Nagashima T, Arase T, Asada H, Yoshimura Y
    • Journal Title

      Endocrinology. 148(2)

      Pages: 896-902

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜と幹細胞.2007

    • Author(s)
      丸山哲夫, 升田博隆, 梶谷宇, 小野政徳, 吉村泰典
    • Journal Title

      産科と婦人科 74

      Pages: 1635-1643

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells2007

    • Author(s)
      Masanori Ono
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America 104

      Pages: 18700-18705

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 子宮内膜と幹細胞2007

    • Author(s)
      丸山哲夫
    • Journal Title

      産科と婦人科 74

      Pages: 1635-1643

    • Related Report
      2007 Annual Research Report
  • [Presentation] 腹水と血清中における代謝物質の網羅的分析による子宮内膜症特異的な代謝物質の探索.2010

    • Author(s)
      川田陽子、島田智恵、浅田弘法、杉本昌弘、平山明由、阿部しのぶ、古谷正敬、内田浩、浜谷敏生、丸山哲夫、梶谷宇、久慈直昭、吉村泰典、曽我朋義、富田勝
    • Organizer
      第31回日本エンドメトリオーシス学会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] Up-regulation of 5- and 15-lipoxygenases in endometriosis2009

    • Author(s)
      Kajitani T, Maruyama T, Asada H, Yamasaki A, Oda H, Nishikawa S, Uchida H, Yoshimura Y
    • Organizer
      he 25th Annual Meeting of the European Society of Human Reproduction and Embryology
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2009 Final Research Report
  • [Presentation] The Role of uterine smooth muscle stem cells, isolated based on cell surface markers, in myometrial remodeling in the pregnant uterus.2009

    • Author(s)
      Ono M, Maruyama T, Kajitani T, Uchida H, Oda H, Nishikawa S, Kagami M, Arase T, Nagashima T, Masuda H, Morikawa S, Mabuchi Y, Okano H, Matsuzaki Y, Yoshimura Y
    • Organizer
      Society for Gynecologic Investigation's 55th Annual Scientific Meeting
    • Place of Presentation
      Glasgow, Scotland
    • Related Report
      2009 Final Research Report
  • [Presentation] FSH産生下垂体腫瘍症例における卵巣過剰刺激の発症メカニズムの解析.2009

    • Author(s)
      西川明花、丸山哲夫、梶谷宇、内田浩、各務真紀、小田英之、宮崎薫、吉村泰典
    • Organizer
      第55回日本生殖医学会学術講演会
    • Place of Presentation
      金沢
    • Related Report
      2009 Final Research Report
  • [Presentation] 新しい方法で単離された子宮平滑筋幹細胞の妊娠子宮リモデリングにおける役割.2009

    • Author(s)
      小野政徳、丸山哲夫、梶谷宇、内田浩、荒瀬透、小田英之、西川明花、升田博隆、岡野栄之、松崎有未、青木大輔、吉村泰典
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮内膜症組織におけるリポキシゲナーゼ経路関連遺伝子の発現解析.2009

    • Author(s)
      梶谷宇, 丸山哲夫, 浅田弘法, 内田浩, 各務真紀, 小田英之, 西川明花, 山崎彰子, 吉村泰典
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      仙台
    • Related Report
      2009 Final Research Report
  • [Presentation] CE-TOFMSによる子宮内膜症患者腹水のメタボローム解析.2009

    • Author(s)
      川田陽子, 浅田弘法, 杉本昌弘, 平山明由, 阿部しのぶ, 古谷正敬, 内田浩, 浜谷敏生, 梶谷宇, 丸山哲夫, 吉村泰典, 曽我朋義, 冨田勝
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      仙台
    • Related Report
      2009 Final Research Report
  • [Presentation] 腹腔鏡下ダグラス窩子宮内膜症病巣切除術の定型化と疼痛緩和効果に関する検討.2009

    • Author(s)
      浅田弘法, 古谷正敬, 梶谷宇, 内田浩, 丸山哲夫, 吉村泰典, 升田博隆, 岸郁子, 田島敏秀, 寺西貴英, 木挽貢慈
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      仙台
    • Related Report
      2009 Final Research Report
  • [Presentation] 新しい方法で単離された子宮平滑筋幹細胞の妊娠子宮リモデリングにおける役割2009

    • Author(s)
      小野政徳, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] The role of uterine smooth muscle stem cells, isolated based on cell surface markers, in myometrial remodeling in the pregnant uterus2009

    • Author(s)
      Ono M, Maruyama T, Kajitani T, Uchida H, Oda H, Nishikawa S, Kagami M, Arase T, Nagashima T, Masuda H, Morikawa S, Mabuchi Y, Okano Y, Matsuzaki Y, Y oshimura Y
    • Organizer
      56th Society for Gynecologic Investigation
    • Place of Presentation
      Glasgow, Scotland
    • Related Report
      2008 Annual Research Report
  • [Presentation] 表面抗原を用いたヒト子宮平滑筋幹細胞の新しい分離法の開発とその妊娠子宮リモデリングにおける役割2009

    • Author(s)
      小野政徳, 丸山哲夫, 梶谷宇, 内田浩, 荒瀬透, 小田英之, 西川明花, 各務真紀, 浅田弘法, 升田博隆, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第8回日本再生医療学会
    • Place of Presentation
      東京都千代田区
    • Related Report
      2008 Annual Research Report
  • [Presentation] CE-TOFMSによる子宮内膜症患者腹水のメタボローム解析2009

    • Author(s)
      川田陽子, 浅田弘法, 杉本昌弘, 平山明由, 阿部しのぶ, 古谷正敬, 内田浩, 浜谷敏生, 梶谷宇, 丸山哲夫, 吉村泰典, 曽我朋義, 勝冨
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      宮城県仙台市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮内膜症組織におけるリポキシゲナーゼ経路関連遺伝子の発現解析2009

    • Author(s)
      梶谷宇, 丸山哲夫, 浅田弘法, 内田浩, 各務真紀, 小田英之, 西川明花, 山崎彰子, 吉村泰典
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      宮城県仙台市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 腹腔鏡下ダグラス窩子宮内膜症病巣切除術の定型化と疼痛緩和効果に関する検討2009

    • Author(s)
      浅田弘法, 古谷正敬, 梶谷宇, 内田浩, 丸山哲夫, 吉村泰典, 升田博隆, 岸郁子, 田島敏秀, 寺西貴英, 木挽貢慈
    • Organizer
      第30回日本エンドメトリオーシス学会
    • Place of Presentation
      宮城県仙台市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト子宮内膜幹様細胞の同定・分離とその幹細胞特性の機能解析.2008

    • Author(s)
      升田博隆, 丸山哲夫, 小野政徳, 長島隆, 梶谷宇, 内田浩, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第13回日本生殖内分泌学会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-29
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト子宮内膜幹様細胞の同定. 分離とその幹細胞特性の機能解析2008

    • Author(s)
      升田博隆, 丸山哲夫, 小野政徳, 長島隆, 梶谷宇, 内田浩, 浅田弘法, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第13回日本生殖内分泌学会
    • Place of Presentation
      大阪市北区
    • Year and Date
      2008-11-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] Laparoscopic treatment of rectovaginal endometriosis(Japanese experience).2008

    • Author(s)
      Asada H, Furuya M, Uchida H, Maruyama T, Kobiki K, Kajitani T, Yoshimura Y
    • Organizer
      9th Annual Congress of APAGE
    • Place of Presentation
      Daegu, Korea
    • Related Report
      2009 Final Research Report
  • [Presentation] Isolation and functional analysis of putative human endometrial stem/progenitor cells.2008

    • Author(s)
      Masuda H, Maruyama T, Ono M, Kajitani T, Okano H, Yoshimura Y
    • Organizer
      The 24th European Society of Human Reproduction and Embryology.
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2009 Final Research Report
  • [Presentation] UDP-glucose and its receptor P2Y14 as a new innate immune system in the female reproductive tract.2008

    • Author(s)
      Arase T, Maruyama T, Uchida H, Kajitani T, Ono M, Kagami M, Asada H, Yoshimura Y
    • Organizer
      Society for Gynecologic Investigation's 55th Annual Scientific Meeting.
    • Place of Presentation
      San Diego, USA
    • Related Report
      2009 Final Research Report
  • [Presentation] N-Cadherin Regulates Epithelio-Mesenchymal Transition and Endometrial Ephithelial Cell Dynamics during Human Implantation.2008

    • Author(s)
      Uchida H, Maruyama T, Arase T, Ono M, Kajitani T, Kagami M, Oda H, Nishikawa S, Yoshimura Y
    • Organizer
      Society for Gynecologic Investigation's 55th Annual Scientific Meeting.
    • Place of Presentation
      San Diego, USA
    • Related Report
      2009 Final Research Report
  • [Presentation] Expression analysis of pain-related genesin endometriosis and adenomyosis.2008

    • Author(s)
      Kajitani T, Maruyama T, Asada H, Ono M, Arase T, Kagami M, Oda H, Nishikawa S, Uchida H, Yoshimura Y
    • Organizer
      10th World Congress on Endometriosis.
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2009 Final Research Report
  • [Presentation] Genome-wide approaches for identification of novel endometriosis-associated genes.2008

    • Author(s)
      Maruyama T, Kajitani T, Oda H, Nishikawa S, Arase T, Kagami M, Ono M, Asada H, Uchida H, Yoshimura Y
    • Organizer
      10th World Congress on Endometriosis.
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮内膜におけるP2RY14を介した新たな粘膜防御機構.2008

    • Author(s)
      荒瀬透, 丸山哲夫, 内田浩, 梶谷宇, 西川明花, 小田英之, 各務真紀, 浅田弘法, 吉村泰典
    • Organizer
      第23回日本生殖免疫学会学術集会
    • Place of Presentation
      富山
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮平滑筋幹細胞の新しい分離法とその機能解析.2008

    • Author(s)
      小野政徳, 丸山哲夫, 梶谷宇, 内田浩, 荒瀬透, 小田英之, 西川明花, 長島隆, 升田博隆, 馬渕洋, 森川暁, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第81回日本内分泌学会学術総会
    • Place of Presentation
      青森
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト着床モデルにおけるepithelial-to-mesenchymal transition -N-cadherinの時期特異的機能関与-.2008

    • Author(s)
      内田浩, 丸山哲夫, 荒瀬透, 小野政徳, 各務真紀, 小田英之, 西川明花, 梶谷宇, 浅田弘法, 青木大輔, 吉村泰典
    • Organizer
      第60回日本産婦人科学会学術講演
    • Place of Presentation
      横浜
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト雌性生殖器官における新しい感染防御システム-g蛋白共役型受容体P2Y14とそのリガンドUDP-glucose-.2008

    • Author(s)
      荒瀬透, 丸山哲夫, 内田浩, 梶谷宇, 小野政徳, 小田英之, 西川明花, 各務真紀, 浅田弘法, 青木大輔, 吉村泰典
    • Organizer
      第60回日本産婦人科学会学術講演会
    • Place of Presentation
      横浜
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒストン脱アセチル化酵素阻害剤HC toxinによるhCG分泌および細胞増殖を標的にした絨毛性疾患の制御.2008

    • Author(s)
      太田邦明, 丸山哲夫, 内田浩, 小野政徳, 梶谷宇, 荒瀬透, 森田峰人, 吉村泰典
    • Organizer
      第60回日本産婦人科学会学術講演会
    • Place of Presentation
      横浜
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮内膜症・腺筋症由来疼痛に関連する遺伝子の発現解析.2008

    • Author(s)
      梶谷宇, 丸山哲夫, 浅田弘法, 小野政徳, 荒瀬透, 小田英之, 西川明花, 内田浩, 吉村泰典
    • Organizer
      第29回エンドメトリオーシス研究会
    • Place of Presentation
      高知
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮内膜症関連遺伝子同定のための新しいアプローチ.2008

    • Author(s)
      丸山哲夫, 梶谷宇, 小田英之, 西川明花, 荒瀬透, 内田浩, 浅田弘法, 吉村泰典
    • Organizer
      第29回エンドメトリオーシス研究会
    • Place of Presentation
      高知
    • Related Report
      2009 Final Research Report
  • [Presentation] Laparoscopic treatment of rectovaginal endometriosis (Japanese experience)2008

    • Author(s)
      Asada H, Furuya M, Uchid a H, Maruyama T, Kobiki K, Kajitani T, Yoshimura Y
    • Organizer
      9th Asia Pasific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE)
    • Place of Presentation
      Daegu, Korea
    • Related Report
      2008 Annual Research Report
  • [Presentation] Isolation and functional analysis of putative human endometr ial stem/ progenitor cells2008

    • Author(s)
      Masuda H, Maruyama T, Ono M, Kajitani T, Okano H, Yoshimura Y
    • Organizer
      24th European society of human reproduction and Embryology (ESHRE)
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト着床モデルにおけるepithelial-to-mesenchymal transition N-cadherin-の時期特異的機能関与-2008

    • Author(s)
      内田浩, 丸山哲夫, 荒瀬透, 小野政徳, 各務真紀, 小田英之, 西川明花, 梶谷宇, 浅田弘法, 青木大輔, 吉村泰典
    • Organizer
      第60回日本産科婦人科学会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒストン脱アセチル化酵素阻害剤HC toxinによるhCG分泌および細胞増殖を標的にした絨毛性疾患の制御2008

    • Author(s)
      太田邦明, 丸山哲夫, 内田浩, 小野政徳, 梶谷宇, 荒瀬透, 森田峰人, 吉村泰典
    • Organizer
      第60回日本産婦人科学会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮平滑筋幹細胞の新しい分離法とその機能解析2008

    • Author(s)
      小野政徳, 丸山哲夫, 梶谷宇, 内田浩, 荒瀬透, 小田英之, 西川明花, 長島隆, 升田博隆, 馬渕洋, 森川暁, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第81回日本内分泌学会学術総会
    • Place of Presentation
      青森県弘前市
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト雌性生殖器官における新しい感染防御システム-G蛋白共役型受容体P2Y14とそのリガンドUDP-glucose-2008

    • Author(s)
      荒瀬透, 丸山哲夫, 内田浩, 梶谷宇, 小野政徳, 小田英之, 西川明花, 各務真紀, 浅田弘法, 青木大輔, 吉村泰典
    • Organizer
      第60回日本産科婦人科学会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 子宮内膜におけるP2RY14を介した新たな粘膜防御機構2008

    • Author(s)
      荒瀬透, 丸山哲夫, 内田浩, 梶谷宇, 西川明花, 小田英之, 各務真紀, 浅田弘法, 吉村泰典
    • Organizer
      第23回日本生殖免疫学会
    • Place of Presentation
      富山県富山市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 妊娠子宮における子宮筋side population細胞の役割2007

    • Author(s)
      小野政徳
    • Organizer
      第12回日本生殖内分泌学会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-19
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒト子宮平滑筋成体幹細胞の同定とその機能解析2007

    • Author(s)
      小野政徳
    • Organizer
      第49回日本平滑筋学会総会
    • Place of Presentation
      奈良
    • Year and Date
      2007-07-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] OCT-4 expression in human myometrium.2007

    • Author(s)
      Ono M, Maruyama T, Kajitani T, Uchida H, Masuda H, Nagashima T, Arase T, Ohta K, Asada H, Yoshimura Y
    • Organizer
      AOCOG2007
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Final Research Report
  • [Presentation] Src kinase activity is essential for decidualization of human endometrial stromal cells.2007

    • Author(s)
      Nagashima T, Maruyama T, Uchida H, Kajitani T, Ono M, Arase T, Kagami M, Ohta K, Asada H, Yoshimura Y
    • Organizer
      The 23th Annual Meeting of the European Society of Human Reproduction and Embryology
    • Place of Presentation
      Lyon, France
    • Related Report
      2009 Final Research Report
  • [Presentation] Reconstruction and in vivo bioluminescence imaging of human endometrium in immunodeficient mice: its potential application as an endometriosis model.2007

    • Author(s)
      Masuda H, Maruyama T, Nagashima T, Ono M, Kajitani T, Ohta K, Arase T, Kagami M, Asada H, Okano H, Matsuzaki Y, Yoshimura Y
    • Organizer
      The 23th Annual Meeting of the European Society of Human Reproduction and Embryology
    • Place of Presentation
      Lyon, France
    • Related Report
      2009 Final Research Report
  • [Presentation] 核移行転写因子STAT5の上流シグナル分子としてSRCチロシンキナーゼはヒト子宮内膜脱落膜化を制御する.2007

    • Author(s)
      長島隆, 丸山哲夫, 内田浩, 梶谷宇, 小野政徳, 荒瀬透, 各務真紀, 浅田弘法, 吉村泰典
    • Organizer
      第52回日本生殖医学会学術講演会
    • Place of Presentation
      秋田
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト子宮平滑筋成体幹細胞の同定とその機能解析.2007

    • Author(s)
      小野政徳, 丸山哲夫, 升田博隆, 梶谷宇, 長島隆, 荒瀬透, 太田邦明, 各務真紀, 小田英之, 浅田弘法, 伊藤守, 内田浩, 岡野栄之, 松崎有未, 吉村泰典
    • Organizer
      第49回日本平滑筋学会総会
    • Place of Presentation
      奈良
    • Related Report
      2009 Final Research Report
  • [Presentation] 疼痛関連遺伝子Nerve Growth Factorの子宮内膜症・腺筋症における発現解析.2007

    • Author(s)
      梶谷宇、丸山哲夫、浅田弘法、内田浩、升田博隆、長島隆、小野政徳、荒瀬透、各務真紀、太田邦明、吉村泰典
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Srcキナーゼ活性はヒト子宮内膜間質細胞の脱落膜化に必須である.2007

    • Author(s)
      長島隆, 丸山哲夫, 内田浩, 梶谷宇, 荒瀬透, 小野政徳, 各務真紀, 吉村泰典
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト子宮内膜再生モデルマウスを用いた内膜幹細胞解析システムの開発.2007

    • Author(s)
      升田博隆, 丸山哲夫, 長島隆, 小野政徳, 梶谷宇, 内田浩, 浅田弘法, 岡野栄之, 松崎有未, 青木大輔, 吉村泰典
    • Organizer
      第59回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] アデノウィルスベクターによるSrcチロシンキナーゼを標的にしたヒト子宮内膜脱落膜化の制御.2007

    • Author(s)
      長島隆, 丸山哲夫, 内田浩, 梶谷宇, 荒瀬透, 小野政徳, 各務真紀, 太田邦明, 青木大輔, 吉村泰典
    • Organizer
      第59回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Presentation] 子宮内膜感染防御におけるG蛋白共役型受容体P2Y14/GPR105の役割.2007

    • Author(s)
      荒瀬透, 丸山哲夫, 内田浩, 梶谷宇, 小野政徳, 長島隆, 各務真紀, 太田邦明, 青木大輔, 吉村泰典
    • Organizer
      第59回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.keio.ac.jp/english/research/atoz_lifesci.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.keio.ac.jp/english/research/atoz_lifesci.html

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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