| Budget Amount *help |
¥27,040,000 (Direct Cost: ¥20,800,000、Indirect Cost: ¥6,240,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2008: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2007: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
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| Research Abstract |
Bone remodeling optimizes bone strength and mineral metabolism. Control of bone remodeling requires a tightly orchestrated interplay among osteoblasts (bone forming cells), osteoclasts (bone resorbing cells) in bone surface and osteocytes, which embedded into bone. To identify the regulation factor of bone remodeling, we performed a genome-wide screening of these bone cells and in vivo analysis of gene targeting mice.
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