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Genome scale prediction of eukaryotic pseudoknotted non-coding RNAs

Research Project

Project/Area Number 19700272
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Bioinformatics/Life informatics
Research InstitutionHirosaki University

Principal Investigator

TANEDA Akito  Hirosaki University, 大学院・工学研究科, 助教 (70332492)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥1,840,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥800,000 (Direct Cost: ¥800,000)
Keywordsバイオインフォマティクス / 生体生命情報学 / RNA / ゲノム / 遺伝子 / 遺伝的アルゴリズム / 二次構造
Research Abstract

独自に開発したRNA構造アライメントのための遺伝的アルゴリズム(Cofolga2)と並列計算システムを用いて、酵母菌 S. serevisiaeとその近縁種6種の間でペアワイズRNA 構造アライメントによる配列比較を行い、新規非翻訳RNA候補の網羅的予測を行った。配列類似度の低い(50%以下)アライメントを予測の対象とし非翻訳RNA 候補を非タンパク質遺伝子コード領域から714個、タンパク質遺伝子コード領域から1,311個予測することができた。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (13 results)

All 2009 2008 2007 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (9 results) Remarks (2 results)

  • [Journal Article] An efficient genetic algorithm for structural RNA pairwise alignment and its application to non-coding RNA discovery in yeast2008

    • Author(s)
      A. Taneda
    • Journal Title

      BMC Bioinformatics 9

      Pages: 521-521

    • Related Report
      2008 Annual Research Report 2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pairwise genome comparison for finding functional RNAs with low sequence identity2007

    • Author(s)
      A. Taneda
    • Journal Title

      The Proceedings of the 2007 Annual Conference of the Japanese Society for Bioinformatics

    • Related Report
      2008 Final Research Report 2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Computational RNA sequence design2009

    • Author(s)
      A.Taneda
    • Organizer
      The Third General Meeting of ACCMS-VO (Asian Consortium on Computational Science - Virtual Organization)
    • Place of Presentation
      Matsushima,Miyagi,Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Computational RNA sequence design2009

    • Author(s)
      A.Taneda
    • Organizer
      The Third General Meeting of ACCMS-VO (Asian Consortium on Computational Science-Virtual Organization
    • Place of Presentation
      Matsushima, Miyagi, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Sampling Approach for Predicting Single-Stranded Regions in the Consensus Structure of Aligned RNA Sequences2008

    • Author(s)
      A. Taneda
    • Organizer
      THE 2nd TAIWAN-JAPAN YOUNG RESEARCHERS CONFERENCE ON COMPUTATIONAL AND SYSTEMS BIOLOGY
    • Place of Presentation
      Odaiba, Tokyo, Japan
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Pairwise genome comparison for finding functional RNAs with low sequence identity2007

    • Author(s)
      A.Taneda
    • Organizer
      The 2007 Annual Conference of Japanese Society for Bioinformatics
    • Place of Presentation
      日本科学未来館, 東京都江東区
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 塩基対形成確率アライメントとサポートベクターマシーンによる非翻訳RNA予測2007

    • Author(s)
      種田晃人
    • Organizer
      新しいRNA/RNPを見つける会
    • Place of Presentation
      理化学研究所バイオリソースセンター, 茨城県つくば市
    • Related Report
      2008 Final Research Report
  • [Presentation] C/D or H/ACA snoRNP proteins do not influence the nucleolar localization of C. elegans CeR-2/CeN21 RNA2007

    • Author(s)
      Y.Hokii, M. Shimoyama, A.Taneda et al.
    • Organizer
      16TH INTERNATIONAL C. ELEGANS MEETING
    • Place of Presentation
      University of California, Los Angeles, USA.
    • Related Report
      2008 Final Research Report
  • [Presentation] Alignment, gene finding, and clustering of structural RNAs by an efficient genetic algorithm2007

    • Author(s)
      A.Taneda
    • Organizer
      15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) & 6th European Conference on Computational Biology (ECCB)
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] C/D or H/ACA snoRNP proteins do not influence the nucleolar localization of C. elegans CeR-2/CeN21 RNA2007

    • Author(s)
      Y. Hokii, M. Shimoyama, A. Taneda, et. al.
    • Organizer
      16TH INTERNATIONAL C. ELEGANS MEETING
    • Place of Presentation
      University of California, Los Angeles, USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] 塩基対形成確率アライメントとサポートベクターマシーンによる非翻訳RNA予測2007

    • Author(s)
      種田 晃人
    • Organizer
      新しいRNA/RNPを見つける会
    • Place of Presentation
      理化学研究所バイオリソースセンター,茨城県つくば市
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://rna.eit.hirosaki-u.ac.jp/cofolga2/new/

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://rna.eit.hirosaki-u.ac.jp/cofolga2/new/

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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