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Study for role of Notch signaling in neural development of vertebrates

Research Project

Project/Area Number 19700286
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research InstitutionTohoku University

Principal Investigator

OMI Minoru  Tohoku University, 大学院生命科学研究科, 助教 (00400416)

Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,680,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥1,600,000 (Direct Cost: ¥1,600,000)
Keywords脳 / 神経 / 発生 / Notch / 分化 / 網膜視蓋投射 / 投射 / 遺伝子発現 / 初期発生 / 体節
Research Abstract

本研究は、最も複雑且つ極めて高度な機能を有する動物特有の組織である脳・神経組織の分化・形成に焦点を当てた。新規のNotchシグナル関連遺伝子snoが中枢神経系において神経細胞の分化/未分化を制御していることが示唆された。また、視神経が脳に投射する際の新たな経路が発見された。これは脳での視覚情報処理機構に関して新たな知見を与えるものである。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (4 results)

All 2008 2006

All Presentation (4 results)

  • [Presentation] Novel paths of retinotectal projection in chick embryos2008

    • Author(s)
      尾身実
    • Organizer
      Tohoku University-Fudan University Neuroscience Workshop for Young Scientists
    • Place of Presentation
      上海、中国
    • Year and Date
      2008-10-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] Novel paths of retinotectal projection in chick embryos2008

    • Author(s)
      尾身実
    • Organizer
      Tohoku University-Fudan University Neuroscience Workshop for Young Scientists
    • Place of Presentation
      上海
    • Related Report
      2008 Final Research Report
  • [Presentation] Functions of strawberry notch 1, a gene functionally related to Notch signaling, in early development of zebrafish embryos2006

    • Author(s)
      尾身実
    • Organizer
      第20回国際生化学・分子生物学会議
    • Place of Presentation
      京都
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼブラフィッシュ胚発生における Notch 関連因子 strawberry notch 1 の機能解析2006

    • Author(s)
      尾身実
    • Organizer
      日本発生生物学会39回大会
    • Place of Presentation
      広島
    • Related Report
      2008 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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