Regulation of temporal and area specific expression of netrin-1 in the developing dorsal spinal cord
| Project/Area Number |
19700297
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | Kumamoto University |
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Principal Investigator |
WATANABE Keisuke Kumamoto University, 大学院・生命科学研究部, 助教 (20446264)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥540,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | netrin-1 / 軸索誘導 / 発現調節 / 脊髄 / DRG / netrin1 / netrin 1 |
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| Research Abstract |
We revealed that guidance molecule netrin-1 attracts ventral-ward migration of dorsal interneurons in the developing spinal cord. Furthermore, Gsg1, which is known to regulate neuroblast migration in C. elegans, is required for proper radial migration and dendrite formation of glutamatergic neurons during development of the cerebral cortex.
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Report
(4 results)
Research Products
(19 results)
