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Elucidation of mechanisms underlying formation of laminar structures of the brain using Drosophila visual system

Research Project

Project/Area Number 19700316
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Nerve anatomy/Neuropathology
Research InstitutionKanazawa University

Principal Investigator

SATO Makoto  Kanazawa University, フロンティアサイエンス機構, 特任准教授 (30345235)

Research Collaborator TABATA Tetsuya  東京大学, 分子細胞生物学研究所, 教授 (10183865)
ITO Kei  東京大学, 分子細胞生物学研究所, 准教授 (00311192)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥3,780,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥1,700,000 (Direct Cost: ¥1,700,000)
Keywords脳・神経 / 神経科学 / 発生・分化 / 遺伝学 / 遺伝子 / ショウジョウバエ / 視覚系 / メダラ神経節
Research Abstract

ショウジョウバエ視覚中枢のメダラ神経節の発生過程を制御する分子機構を解析し、転写因子Drfの発現によって規定される神経細胞は約60種存在するメダラ神経細胞のうち9種の神経細胞を構成すること、高次の神経節であるロビュラの第1層および第4層特異的に投射すること、ロビュラに至る投射は幼虫期においてすでに見られることがわかった。また、神経細胞の種類と細胞体の位置には強い相関があることがわかった。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (24 results)

All 2008 2007 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (14 results) Remarks (3 results)

  • [Journal Article] Larval cells become imaginal cells under the control of homothorax prior to metamorphosis in the Drosophila tracheal system2008

    • Author(s)
      Sato,M., Kitada, Y. and Tabata, T.
    • Journal Title

      Developmental Biology 318

      Pages: 247-57

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT2008

    • Author(s)
      Yasugi, T., Umetsu, D., Murakami, S., Sato, M. and Tabata, T.
    • Journal Title

      Development 135

      Pages: 1471-80

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is neaativelv reaulated by JAK/STAT2008

    • Author(s)
      八杉徹雄、梅津大輝、村上智史、佐藤純、多羽田哲也
    • Journal Title

      Development 135

      Pages: 1471-1480

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Larval cells become imaginal cells under the control of homothorax prior to metamorohosis in the Drosophila tracheal system2008

    • Author(s)
      佐藤純、北田祐介、多羽田哲也
    • Journal Title

      Developmental Biology 318

      Pages: 247-257

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT2008

    • Author(s)
      八杉徹雄、梅津大輝、村上智史、佐藤純、多羽田哲也
    • Journal Title

      Development 135

      Pages: 1471-1480

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Larval cells become imaginal cells under the control of homothorax prior to metamorphosis in the Drosophila tracheal system2008

    • Author(s)
      佐藤純、北田祐介、多羽田哲也
    • Journal Title

      Developmental Biology (印刷中)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk2007

    • Author(s)
      Murakami, S., Umetsu, D., Maeyama, Y., Sato, M., Yoshida, S. and Tabata, T.
    • Journal Title

      Development 134

      Pages: 1539-48

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] 発生過程のショウジョウバエ視覚中枢を区画化する遺伝子ネットワークの解析2008

    • Author(s)
      長谷川恵理, 北田祐介, 多羽田哲也, 佐藤純
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] 発生過程のショウジョウバエ視覚中枢において同心円状に発現する転写因子群の機能解析2008

    • Author(s)
      北田祐介, 長谷川恵理, 田井美也子, 多羽田哲也, 佐藤純
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2008

    • Author(s)
      佐藤純
    • Organizer
      金沢大学革新脳科学COEシンポジウム Neurobiology of Drosophila, 口頭発表
    • Place of Presentation
      金沢
    • Year and Date
      2008-08-21
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2008

    • Author(s)
      Sato, M.
    • Organizer
      International Symposium on Innovative Brain Science for Development, Learning, Memory and Autism, 口頭発表
    • Place of Presentation
      金沢
    • Year and Date
      2008-07-19
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2008

    • Author(s)
      佐藤純、北田祐介、田井美也子、梅津大輝、多羽田哲也
    • Organizer
      第41回日本発生生物学会大会, ポスター発表
    • Place of Presentation
      徳島
    • Year and Date
      2008-05-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2008

    • Author(s)
      佐藤純、北田祐介、田井美也子、梅津大輝、多羽田哲也
    • Organizer
      第41回日本発生生物学会大会
    • Place of Presentation
      徳島
    • Year and Date
      2008-05-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] ショウジョウバエ成虫脳における同心円ゾーンと細胞移動による神経回路の構築2007

    • Author(s)
      佐藤純、田井美也子、梅津大輝、北田祐介、多羽田哲也
    • Organizer
      第30回日本分子生物学会年会, 口頭発表
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-14
    • Related Report
      2008 Final Research Report
  • [Presentation] ショウジョウバエ成虫脳における同心円ゾーンと細胞移動による神経回路の構築2007

    • Author(s)
      佐藤純、田井美也子、梅津大輝、北田祐介、多羽田哲也
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] ショウジョウバエ成虫脳における同心円ゾーンと細胞移動による神経回路の構築2007

    • Author(s)
      佐藤純
    • Organizer
      発生生物学会秋季シンポジウム2007
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2007

    • Author(s)
      Sato, M., Kitada, Y., Tai, M., Umetsu, D. and Tabata, T.
    • Organizer
      Cold Spring Harbor Laboratory Meeting on Neurobiology of Drosophila, ポスター発表
    • Place of Presentation
      ニューヨーク
    • Year and Date
      2007-10-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2007

    • Author(s)
      佐藤純、北田祐介、田井美也子、梅津大輝、多羽田哲也
    • Organizer
      Cold Spring Harbor Laboratory Meeting on Neurobiology of Drosophila
    • Place of Presentation
      ニューヨークコールドスプリングハーバー
    • Year and Date
      2007-10-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] ショウジョウバエ成虫脳における同心円ゾーンと細胞移動による神経回路の構築2007

    • Author(s)
      佐藤純、田井美也子、梅津大輝、多羽田哲也
    • Organizer
      東京大学生命科学研究ネットワークシンポジウム2007
    • Place of Presentation
      東京
    • Year and Date
      2007-09-15
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2007

    • Author(s)
      Sato, M.
    • Organizer
      Kornberg Family Symposium: Developmental Biology of Compartment and Signaling Center
    • Place of Presentation
      東京
    • Year and Date
      2007-07-24
    • Related Report
      2008 Final Research Report
  • [Presentation] Concentric zones, cell migrations and neuronal circuits in the Drosophila brain2007

    • Author(s)
      佐藤純、田井美也子、梅津大輝、多羽田哲也
    • Organizer
      日本ショウジョウバエ研究会第8回集会
    • Place of Presentation
      淡路夢舞台
    • Year and Date
      2007-07-03
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページアドレス

    • URL

      http://fsosato.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://fsosato.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://fsosato.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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