| Project/Area Number |
19700410
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
内田 勝美 Tokyo University of Science, 理学部, 嘱託助教 (50385514)
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| Project Period (FY) |
2007 – 2008
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| Project Status |
Completed (Fiscal Year 2008)
|
| Budget Amount *help |
¥3,620,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | 温度応答性高分子 / バイオセンシング / シグナル増幅効果 / 相転移 / 高分子ミセル / シグナル増幅 / 表面プラズモン共鳴 |
|---|
| Research Abstract |
Detection of the specific interaction between biomacromolecules with surface plasmon resonance (SPR) measurements is to utilize the change of the refractive index induced by binding between biomacromolecules. In this study, we utilized thermo-responsive polymeric micelle for SPR biosensing, resulting in amplification of SPR signal by the phase transition of the micelle that induced by binding to biomacromolecule.
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