Alteration of intraarticular structures during contracture formation following central paralysis

• Project/Area Number: 19700443
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Saitama Prefectural University
• Principal Investigator: MORIYAMA Hideki Saitama Prefectural University, 保健医療福祉学部, 講師 (10438111)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,600,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥300,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2007: ¥2,300,000 (Direct Cost: ¥2,300,000)
• Keywords: 関節拘縮 / 中枢性麻痺 / 脊髄損傷 / 関節構造 / 筋緊張 / 関節内結合組織 / 関節軟骨

Research Abstract

中枢性麻痺に伴う関節拘縮は、臨床での対応に苦慮する合併症である。本研究課題は、関節拘縮の原因となる関節構造の変性の局在を明らかにすることを目的とした。その結果、脊髄損傷後の関節軟骨の変性は、機械的刺激の欠如あるいは除神経の影響のいずれかのみが原因となり生じないことが示された。また関節拘縮の治療において、弛緩性麻痺あるいは痙性麻痺に関わらず、筋の変化を中心に関節構造内の変化にも着目する必要性が示された。

Research Products

• [Journal Article] Contrasting alteration patterns of different cartilage plates in knee articular cartilage after spinal cord injury inrats (2009)
  • Author(s): Moriyama H、Nishihara K、Hosoda M、Saka Y、Kanemura N、Takayanagi K、Yoshimura O、Tobimatsu Y
  • Journal Title: Spinal cord 47 Pages: 218-224
  • Peer Reviewed
• [Journal Article] Contrasting alteration patterns of different cartilage plates in knee articular cartilage after spinal cord injury in rais (2009)
  • Author(s): Moriyama H
  • Journal Title: Spinal Cord 47 Pages: 218-224
  • Peer Reviewed
• [Journal Article] ラット脊髄損傷後早期の関節拘縮進行過程における筋と関節構成体の関与 (2008)
  • Author(s): 森山英樹、角田育子、八戸美葉、坂ゆかり、武本秀徳、河野一郎、細田昌孝、高柳清美、伊藤俊一、飛松好子
  • Journal Title: 理学療法学 35 Pages: 318-324
  • NAID: 110007008615
  • Peer Reviewed
• [Journal Article] ラット脊髄損傷後の膝関節における軟骨細胞数とプロテオグリカン量の組織学的変化 (2008)
  • Author(s): 森山英樹、吉村理、高柳清美、小林隆司、細田昌孝、金村尚彦、今北英高、白濱勲二、鈴木陽介、荒木智子、須永康代、飛松好子
  • Journal Title: 専門リハビリテーション 7 Pages: 34-41
  • NAID: 40016029844
  • Peer Reviewed
• [Journal Article] Alteration in articular cartilage of rat knee joints after spinal cord injury (2008)
  • Author(s): Moriyama H、Yoshimura O、Kawamata S、Takayanagi K、Kurose T、Kubota A、HosodaM、Tobimatsu Y
  • Journal Title: Osteoarthritis and cartilage 16 Pages: 392-398
  • Peer Reviewed
• [Journal Article] ラット脊髄損傷後早期の関節拘縮進行過程における筋と関節構成体の関与 (2008)
  • Author(s): 森山英樹
  • Journal Title: 理学療法学 35 Pages: 318-324
  • NAID: 110007008615
  • Peer Reviewed
• [Journal Article] Alteration in articular cartilage of rat Knee Joints after spinal cord injury (2008)
  • Author(s): 森山 英樹
  • Journal Title: Osteoarthritis and cartilage 16・3 Pages: 392-398
  • Peer Reviewed
• [Journal Article] ラット脊髄損湯後の膝関即における軟骨細胞藪とフロテオグリカン量の組織学的変化 (2008)
  • Author(s): 森山 英樹
  • Journal Title: 専門リハビリテーション 7 Pages: 34-41
  • Peer Reviewed
• [Journal Article] Alteration of knee joint connective tissues during contracture formation in spastic rats after an experimentally induced spinal cord injury (2007)
  • Author(s): Moriyama H、Yoshimura O、Kawamata S、Takemoto H 、Saka Y 、Tobimatsu Y
  • Journal Title: Connective tissue research 48 Pages: 180-187
  • NAID: 10021232123
  • Peer Reviewed
• [Journal Article] Alteration of knee joint connective tissues during contracture formati on in spastic rats after an experimentally induced spinal cord injury (2007)
  • Author(s): 森山 英樹
  • Journal Title: Connective tissue research 48・4 Pages: 180-187
  • Peer Reviewed
• [Presentation] Comparison of muscular and articular factors during join tcontracture formation in acute spinal cord injury (2008)
  • Author(s): Moriyama H
  • Organizer: 10th International Congress of the Asian Confederation for Physical Therapy (ACPT)
  • Place of Presentation: 幕張メッセ・千葉
  • Year and Date: 2008-08-30
• [Presentation] Comparison of muscular and articular factors during joint contracture formation in acute spinal cord injury (2008)
  • Author(s): Moriyama H
  • Organizer: 10th International Congress of the Asian Confederation for Physical Therapy (ACPT)
  • Place of Presentation: 幕張メッセ・千葉
  • Year and Date: 2008-08-30
• [Presentation] 脊髄損傷ラットモデルにおける膝関節軟骨の変性の組織形態計測的分析 (2008)
  • Author(s): 森山英樹
  • Organizer: 第43回日本理学療法学術大会
  • Place of Presentation: 福岡国際センター・福岡
  • Year and Date: 2008-05-16
• [Presentation] Contrasting alterations of anterior and posterior articular cartilage of rat knee joints after spinal cord injury (2007)
  • Author(s): Moriyama H
  • Organizer: 15th International World Confederation for Physical Therapy (WCPT) Congress
  • Place of Presentation: カナダ・バンクーバー
  • Year and Date: 2007-06-06
• [Presentation] Contrasting alterations of anterior and posterior articular cartilage of r at knee joints after spinal cord injury (2007)
  • Author(s): 森山 英樹
  • Organizer: 15th International WCPT Congress
  • Place of Presentation: カナダ・バンクーバー